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cvpA cvpA guaA guaA purN purN EDV01669.1 EDV01669.1 purL purL purB purB guaB guaB purD purD purH purH purC purC EDV00461.1 EDV00461.1 purE purE purA purA EDU99497.1 EDU99497.1 adk adk hpt hpt xpt xpt surE surE purT purT
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Your Input:
cvpACvpA family protein; COG: NOG17673 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.46. (166 aa)
guaAGMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. (517 aa)
purNPutative phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (189 aa)
EDV01669.1Class II glutamine amidotransferase; KEGG: chu:CHU_2612 9.0e-163 purF; amidophosphoribosyltransferase K00764; COG: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; Psort location: Cytoplasmic, score: 8.96. (627 aa)
purLPutative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1234 aa)
purBKEGG: bth:BT3871 4.8e-212 adenylosuccinate lyase K01756; COG: COG0015 Adenylosuccinate lyase; Psort location: Cytoplasmic, score: 8.96. (449 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (491 aa)
purDKEGG: bth:BT3253 3.9e-178 phosphoribosylamine--glycine ligase K01945; COG: COG0151 Phosphoribosylamine-glycine ligase; Psort location: Cytoplasmic, score: 8.96; Belongs to the GARS family. (424 aa)
purHPutative phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: bfr:BF4101 5.0e-224 phosphoribosylaminoimidazole carboxy formyl formyltransferase K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.96. (508 aa)
purCKEGG: bth:BT4217 5.0e-153 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; COG: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family. (314 aa)
EDV00461.1Hypothetical protein; KEGG: bfr:BF0911 2.0e-190 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: Cytoplasmic, score: 8.96. (383 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
EDU99497.1AICARFT/IMPCHase bienzyme; KEGG: dme:Dmel_CG11089 1.5e-119 CG11089 K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score: 8.96. (392 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (189 aa)
hptKEGG: bfr:BF1119 4.7e-70 putative hypoxanthine guanine phosphoribosyltransferase K00760; COG: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (189 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (261 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (389 aa)
Your Current Organism:
Bacteroides coprocola
NCBI taxonomy Id: 470145
Other names: B. coprocola DSM 17136, Bacteroides coprocola DSM 17136, Bacteroides coprocola M16, Bacteroides coprocola str. DSM 17136, Bacteroides coprocola strain DSM 17136
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