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AQZ80775.1 AQZ80775.1 hemA hemA hemE hemE AQZ80848.1 AQZ80848.1 AQZ82670.1 AQZ82670.1 hemL hemL AQZ82726.1 AQZ82726.1 cysG cysG hemF hemF AQZ83373.1 AQZ83373.1 AQZ83712.1 AQZ83712.1 AQZ80908.1 AQZ80908.1 AQZ82480.1 AQZ82480.1 cyoE cyoE hemC hemC AQZ80357.1 AQZ80357.1 hemH hemH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AQZ80775.1ferredoxin--NADP(+) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (427 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (357 aa)
AQZ80848.1TIGR00701 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
AQZ82670.1Uroporphyrinogen decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
AQZ82726.1Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
cysGuroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (457 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (316 aa)
AQZ83373.1Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AQZ83712.1Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (337 aa)
AQZ80908.1Biliverdin-producing heme oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
AQZ82480.1ferredoxin--NADP(+) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (292 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa)
AQZ80357.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (255 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (338 aa)
Your Current Organism:
Acinetobacter calcoaceticus
NCBI taxonomy Id: 471
Other names: A. calcoaceticus, ATCC 23055, Acinetobacter genomosp. 1, Acinetobacter genomospecies 1, Acinetobacter sp. AV6, Acinetobacter sp. HNR, Acinetobacter sp. STB1, CAIM 17, CCUG 12804, CIP 81.8, DSM 30006, JCM 6842, Micrococcus calcoaceticus, Moraxella calcoacetica, NCCB 22016, NCTC 12983, Neisseria winogradskyi
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