(92 nodes) Positive regulation of proteolysis network (Trachymyrmex cornetzi)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ALC57_02500	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (86 aa)
	ALC57_18773	Coiled-coil domain-containing protein 22 like protein. (523 aa)
	ALC57_18481	Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (649 aa)
	ALC57_18327	Muskelin. (752 aa)
	ALC57_17971	Neuroendocrine protein 7B2. (253 aa)
	ALC57_17695	Caspase Nc; Belongs to the peptidase C14A family. (408 aa)
	ALC57_17694	Proteasome activator complex subunit 3. (238 aa)
	ALC57_16933	Intraflagellar transport protein 57 like protein. (406 aa)
	ALC57_15620	RBR-type E3 ubiquitin transferase. (509 aa)
	ALC57_14638	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (434 aa)
	ALC57_14597	Uncharacterized protein. (120 aa)
	ALC57_14123	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (897 aa)
	ALC57_13254	F-box/WD repeat-containing protein 1A. (530 aa)
	ALC57_11253	Death domain-containing adapter protein BG4. (279 aa)
	ALC57_10512	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (188 aa)
	ALC57_09460	Transcription elongation factor B polypeptide 2. (112 aa)
	ALC57_09303	E3 ubiquitin-protein ligase HECTD1. (2585 aa)
	ALC57_08867	DET1-and DDB1-associated protein 1. (102 aa)
	ALC57_06043	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (279 aa)
	ALC57_05983	Eukaryotic initiation factor 4A-II; Belongs to the DEAD box helicase family. (417 aa)
	ALC57_05012	Proteasome inhibitor PI31 subunit. (280 aa)
	ALC57_03950	RBR-type E3 ubiquitin transferase. (471 aa)
	ALC57_03897	RBR-type E3 ubiquitin transferase. (792 aa)
	ALC57_03241	E3 ubiquitin-protein ligase UBR4. (5202 aa)
	ALC57_02734	Casein kinase I isoform epsilon. (974 aa)
	ALC57_02464	Transcription factor Dp-1. (815 aa)
	ALC57_02044	Poly [ADP-ribose] polymerase. (1211 aa)
	ALC57_00694	GMP synthase [glutamine-hydrolyzing]. (716 aa)
	ALC57_01047	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
	ALC57_00494	Beta-arrestin-1. (469 aa)
	ALC57_18831	Cullin-3; Belongs to the cullin family. (784 aa)
	ALC57_19041	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (127 aa)
	ALC57_17955	Protein zyg-11 like protein B. (785 aa)
	ALC57_17749	Membralin. (646 aa)
	ALC57_17493	F-box-like/WD repeat-containing protein TBL1XR1. (503 aa)
	ALC57_17280	Rhomboid domain-containing protein 1. (246 aa)
	ALC57_17209	Hsp70-binding protein 1. (378 aa)
	ALC57_16530	Proteasomal ubiquitin receptor ADRM1 like protein. (398 aa)
	ALC57_15975	Ubiquitin carboxyl-terminal hydrolase. (856 aa)
	ALC57_15295	Guanine nucleotide-binding protein subunit beta-like protein. (317 aa)
	ALC57_15389	Uncharacterized protein. (272 aa)
	ALC57_14976	Transcription elongation factor B polypeptide 2. (239 aa)
	ALC57_13912	26S proteasome non-ATPase regulatory subunit 10. (230 aa)
	ALC57_14020	Kelch-like protein 10. (648 aa)
	ALC57_13746	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (405 aa)
	ALC57_13419	Transitional endoplasmic reticulum ATPase TER94; Belongs to the AAA ATPase family. (801 aa)
	ALC57_13567	Cullin-2; Belongs to the cullin family. (760 aa)
	ALC57_12327	Bardet-Biedl syndrome 7 protein. (733 aa)
	ALC57_12367	PRA1 family protein. (185 aa)
	ALC57_12441	SH3 domain-containing RING finger protein 3. (910 aa)
	ALC57_12456	RBR-type E3 ubiquitin transferase. (475 aa)
	ALC57_12681	E3 ubiquitin-protein ligase AMFR. (607 aa)
	ALC57_12403	CARD domain-containing protein. (83 aa)
	ALC57_12150	Uncharacterized protein. (221 aa)
	ALC57_12107	Fizzy-related protein like protein. (494 aa)
	ALC57_11100	Proteasome activator complex subunit 4. (1840 aa)
	ALC57_11170	STIP1 homology and U box-containing protein 1. (291 aa)
	ALC57_10881	RBR-type E3 ubiquitin transferase. (470 aa)
	ALC57_10011	Serine/threonine-protein kinase Chk2. (462 aa)
	ALC57_08766	RING-box protein 1A. (106 aa)
	ALC57_08656	Protein expanded. (1254 aa)
	ALC57_08245	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (414 aa)
	ALC57_07999	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (357 aa)
	ALC57_08121	Protein RMD5 like protein A. (392 aa)
	ALC57_07746	Proteasome maturation protein. (111 aa)
	ALC57_07296	Tribbles like protein 2. (360 aa)
	ALC57_07374	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (895 aa)
	ALC57_07494	Uncharacterized protein. (353 aa)
	ALC57_06734	Microtubule-associated tumor suppressor 1 like protein. (1263 aa)
	ALC57_06720	F-box only protein 22. (586 aa)
	ALC57_06735	Serine/threonine-protein kinase 3. (530 aa)
	ALC57_05466	DET1 like protein. (555 aa)
	ALC57_04481	Caspase-10; Belongs to the peptidase C14A family. (444 aa)
	ALC57_04628	RING finger and transmembrane domain-containing protein 2. (457 aa)
	ALC57_04578	RING-type domain-containing protein. (184 aa)
	ALC57_04232	Putative G-protein coupled receptor No9; Belongs to the G-protein coupled receptor 1 family. (545 aa)
	ALC57_04210	E3 ubiquitin-protein ligase RFWD2. (1132 aa)
	ALC57_04235	Serine protease HTRA2, mitochondrial. (433 aa)
	ALC57_03360	WD repeat-containing protein 20. (627 aa)
	ALC57_03795	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (754 aa)
	ALC57_03489	Ubiquitin carboxyl-terminal hydrolase. (803 aa)
	ALC57_03614	Axin-1. (817 aa)
	ALC57_03490	Serine/threonine-protein kinase TBK1. (744 aa)
	ALC57_03528	Protein cortex. (428 aa)
	ALC57_03558	X-box-binding protein 1. (453 aa)
	ALC57_02859	Gamma-secretase subunit pen-2. (104 aa)
	ALC57_02496	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (190 aa)
	ALC57_02499	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (126 aa)
	ALC57_01913	GRB2-related adapter protein. (320 aa)
	ALC57_02119	Ribonucleoside-diphosphate reductase subunit M2. (316 aa)
	ALC57_01785	E3 ubiquitin-protein ligase HRD1. (601 aa)
	ALC57_01354	Ran-binding protein 9. (647 aa)

Your Current Organism:

Trachymyrmex cornetzi

NCBI taxonomy Id: 471704
Other names: T. cornetzi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALC57_00494	ALC57_04232	A0A151JSD1	A0A195EDS6	Beta-arrestin-1.	Putative G-protein coupled receptor No9; Belongs to the G-protein coupled receptor 1 family.	0.691
ALC57_00694	ALC57_01047	A0A151JR18	A0A151JR92	GMP synthase [glutamine-hydrolyzing].	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.405
ALC57_00694	ALC57_03795	A0A151JR18	A0A195EFT4	GMP synthase [glutamine-hydrolyzing].	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.542
ALC57_00694	ALC57_05983	A0A151JR18	A0A151J9B0	GMP synthase [glutamine-hydrolyzing].	Eukaryotic initiation factor 4A-II; Belongs to the DEAD box helicase family.	0.539
ALC57_00694	ALC57_07374	A0A151JR18	A0A195E5M8	GMP synthase [glutamine-hydrolyzing].	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.542
ALC57_00694	ALC57_08245	A0A151JR18	A0A195E2V3	GMP synthase [glutamine-hydrolyzing].	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.410
ALC57_00694	ALC57_12441	A0A151JR18	A0A195DRF7	GMP synthase [glutamine-hydrolyzing].	SH3 domain-containing RING finger protein 3.	0.527
ALC57_00694	ALC57_17209	A0A151JR18	A0A195DDV7	GMP synthase [glutamine-hydrolyzing].	Hsp70-binding protein 1.	0.433
ALC57_01047	ALC57_00694	A0A151JR92	A0A151JR18	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	GMP synthase [glutamine-hydrolyzing].	0.405
ALC57_01047	ALC57_02044	A0A151JR92	A0A151JP23	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Poly [ADP-ribose] polymerase.	0.747
ALC57_01047	ALC57_02464	A0A151JR92	A0A151JNL0	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Transcription factor Dp-1.	0.895
ALC57_01047	ALC57_03360	A0A151JR92	A0A195EFJ7	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	WD repeat-containing protein 20.	0.518
ALC57_01047	ALC57_03528	A0A151JR92	A0A195EH44	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Protein cortex.	0.694
ALC57_01047	ALC57_04210	A0A151JR92	A0A195EE03	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	E3 ubiquitin-protein ligase RFWD2.	0.622
ALC57_01047	ALC57_04235	A0A151JR92	A0A195EE27	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Serine protease HTRA2, mitochondrial.	0.933
ALC57_01047	ALC57_05012	A0A151JR92	A0A151JBV8	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Proteasome inhibitor PI31 subunit.	0.826
ALC57_01047	ALC57_07494	A0A151JR92	A0A195E5S8	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.670
ALC57_01047	ALC57_07746	A0A151JR92	A0A195E4H2	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	Proteasome maturation protein.	0.617
ALC57_01047	ALC57_07999	A0A151JR92	A0A195E2Z9	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	26S protease regulatory subunit 4; Belongs to the AAA ATPase family.	0.999
ALC57_01047	ALC57_08245	A0A151JR92	A0A195E2V3	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.999