(63 nodes) Negative regulation of canonical Wnt signaling pathway network (Trachymyrmex cornetzi)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALC57_05096	Uncharacterized protein. (161 aa)
	ALC57_05119	Uncharacterized protein. (268 aa)
	ALC57_06182	72 kDa type IV collagenase. (326 aa)
	ALC57_07590	Adenomatous polyposis coli protein. (2651 aa)
	ALC57_08561	Uncharacterized protein. (231 aa)
	ALC57_09310	72 kDa type IV collagenase. (298 aa)
	ALC57_09889	Trophoblast glycoprotein. (396 aa)
	ALC57_10298	Serine/threonine-protein kinase LATS1. (1090 aa)
	ALC57_09958	FERM domain-containing protein 8. (454 aa)
	ALC57_10386	Uncharacterized protein. (188 aa)
	ALC57_11009	Uncharacterized protein. (345 aa)
	ALC57_10785	Dual specificity mitogen-activated protein kinase kinase 6. (336 aa)
	ALC57_11068	Uncharacterized protein. (183 aa)
	ALC57_11021	Ran-binding protein 3. (311 aa)
	ALC57_11713	Matrix metalloproteinase-14. (208 aa)
	ALC57_12779	Adenomatous polyposis coli protein. (1026 aa)
	ALC57_02496	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (190 aa)
	ALC57_03614	Axin-1. (817 aa)
	ALC57_03878	Ras-like GTP-binding protein Rho1. (187 aa)
	ALC57_04167	Cell division cycle protein 16 like protein. (659 aa)
	ALC57_04657	N-acetylglucosamine-6-sulfatase. (456 aa)
	ALC57_02499	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (126 aa)
	ALC57_02349	Protein chibby like protein 1. (104 aa)
	ALC57_02500	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (86 aa)
	ALC57_02350	Protein chibby like protein 1. (124 aa)
	ALC57_02360	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (754 aa)
	ALC57_01887	CREB-binding protein. (2516 aa)
	ALC57_01399	Protein ECT2. (1259 aa)
	ALC57_00830	Protein groucho. (752 aa)
	ALC57_12888	Uncharacterized protein. (291 aa)
	ALC57_13254	F-box/WD repeat-containing protein 1A. (530 aa)
	ALC57_14531	Matrix metalloproteinase-14. (273 aa)
	ALC57_15705	Uncharacterized protein. (390 aa)
	ALC57_16270	Uncharacterized protein. (184 aa)
	ALC57_16447	Matrix metalloproteinase-14. (456 aa)
	ALC57_18508	Matrix metalloproteinase-14. (372 aa)
	ALC57_06227	Matrix metalloproteinase-25. (642 aa)
	ALC57_06217	Mitogen-activated protein kinase. (346 aa)
	ALC57_06735	Serine/threonine-protein kinase 3. (530 aa)
	ALC57_06734	Microtubule-associated tumor suppressor 1 like protein. (1263 aa)
	ALC57_07209	C-terminal-binding protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (363 aa)
	ALC57_07857	Casein kinase I isoform alpha. (315 aa)
	ALC57_09389	Transducin-like enhancer protein 3. (859 aa)
	ALC57_09384	Transducin-like enhancer protein 4. (794 aa)
	ALC57_09627	Testican-2. (494 aa)
	ALC57_11241	Protein notum like protein. (566 aa)
	ALC57_13419	Transitional endoplasmic reticulum ATPase TER94; Belongs to the AAA ATPase family. (801 aa)
	ALC57_14257	Kinesin-like protein KIF23. (367 aa)
	ALC57_14875	Paired amphipathic helix protein Sin3a. (1516 aa)
	ALC57_16342	Extracellular sulfatase SULF-1 like protein. (1461 aa)
	ALC57_17185	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (461 aa)
	ALC57_18145	OTU domain-containing protein 5. (585 aa)
	ALC57_19041	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (127 aa)
	ALC57_00197	Uncharacterized protein. (259 aa)
	ALC57_00816	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa)
	ALC57_00703	Protein naked cuticle like protein. (654 aa)
	ALC57_01536	E3 ubiquitin-protein ligase HUWE1. (4158 aa)
	ALC57_02550	Uncharacterized protein. (193 aa)
	ALC57_02747	Matrix metalloproteinase-14. (193 aa)
	ALC57_02684	Uncharacterized protein. (125 aa)
	ALC57_03891	Uncharacterized protein. (128 aa)
	ALC57_04387	Transcription factor SOX-2. (474 aa)
	ALC57_04428	Uncharacterized protein. (184 aa)

Your Current Organism:

Trachymyrmex cornetzi

NCBI taxonomy Id: 471704
Other names: T. cornetzi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALC57_00816	ALC57_03614	A0A151JRG5	A0A195EG87	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Axin-1.	0.724
ALC57_00816	ALC57_03878	A0A151JRG5	A0A195EFA1	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Ras-like GTP-binding protein Rho1.	0.437
ALC57_00816	ALC57_06217	A0A151JRG5	A0A195E8Y6	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Mitogen-activated protein kinase.	0.421
ALC57_00816	ALC57_07590	A0A151JRG5	A0A151J7T2	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Adenomatous polyposis coli protein.	0.621
ALC57_00816	ALC57_07857	A0A151JRG5	A0A195E402	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Casein kinase I isoform alpha.	0.649
ALC57_00816	ALC57_12779	A0A151JRG5	A0A151J0H7	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	Adenomatous polyposis coli protein.	0.621
ALC57_00816	ALC57_13254	A0A151JRG5	A0A151IZN9	Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.	F-box/WD repeat-containing protein 1A.	0.431
ALC57_00830	ALC57_01887	A0A195EMY7	A0A195EL67	Protein groucho.	CREB-binding protein.	0.754
ALC57_00830	ALC57_07209	A0A195EMY7	A0A195E543	Protein groucho.	C-terminal-binding protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.818
ALC57_00830	ALC57_09384	A0A195EMY7	A0A195DZZ7	Protein groucho.	Transducin-like enhancer protein 4.	0.843
ALC57_00830	ALC57_09389	A0A195EMY7	A0A195E002	Protein groucho.	Transducin-like enhancer protein 3.	0.833
ALC57_00830	ALC57_13254	A0A195EMY7	A0A151IZN9	Protein groucho.	F-box/WD repeat-containing protein 1A.	0.484
ALC57_01399	ALC57_02360	A0A195EMC3	A0A195EKB1	Protein ECT2.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.959
ALC57_01399	ALC57_03878	A0A195EMC3	A0A195EFA1	Protein ECT2.	Ras-like GTP-binding protein Rho1.	0.987
ALC57_01399	ALC57_14257	A0A195EMC3	A0A195DL27	Protein ECT2.	Kinesin-like protein KIF23.	0.956
ALC57_01536	ALC57_13419	A0A151JQ00	A0A195DN43	E3 ubiquitin-protein ligase HUWE1.	Transitional endoplasmic reticulum ATPase TER94; Belongs to the AAA ATPase family.	0.467
ALC57_01887	ALC57_00830	A0A195EL67	A0A195EMY7	CREB-binding protein.	Protein groucho.	0.754
ALC57_01887	ALC57_06217	A0A195EL67	A0A195E8Y6	CREB-binding protein.	Mitogen-activated protein kinase.	0.464
ALC57_01887	ALC57_07209	A0A195EL67	A0A195E543	CREB-binding protein.	C-terminal-binding protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.763
ALC57_01887	ALC57_09384	A0A195EL67	A0A195DZZ7	CREB-binding protein.	Transducin-like enhancer protein 4.	0.754