STRINGSTRING
ispF ispF Tcur_0842 Tcur_0842 ispE ispE Tcur_1045 Tcur_1045 Tcur_1075 Tcur_1075 ispH ispH Tcur_1472 Tcur_1472 idi idi dxs dxs Tcur_1860 Tcur_1860 Tcur_2713 Tcur_2713 Tcur_2714 Tcur_2714 Tcur_3027 Tcur_3027 Tcur_3074 Tcur_3074 Tcur_3231 Tcur_3231 ispG ispG dxr dxr Tcur_3474 Tcur_3474 Tcur_3495 Tcur_3495 Tcur_3654 Tcur_3654 Tcur_3890 Tcur_3890 Tcur_3981 Tcur_3981 ispD ispD Tcur_4404 Tcur_4404 Tcur_4616 Tcur_4616
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (156 aa)
Tcur_0842TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: cti:RALTA_B0504 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (314 aa)
Tcur_1045KEGG: gbm:Gbem_1434 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
Tcur_1075Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (271 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (320 aa)
Tcur_1472KEGG: gbm:Gbem_1434 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
idiIsopentenyl-diphosphate delta-isomerase, type 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (191 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa)
Tcur_1860KEGG: bur:Bcep18194_C7151 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Tcur_2713Propanoyl-CoA C-acyltransferase; KEGG: dol:Dole_1551 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
Tcur_2714PFAM: protein of unknown function DUF35; 3-Oxoacyl- [acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: ccs:CCNA_01498 DNA-dependent DNA polymerase III subunit alpha. (465 aa)
Tcur_3027PFAM: Polyprenyl synthetase; KEGG: scl:sce4204 geranyltranstransferase; Belongs to the FPP/GGPP synthase family. (353 aa)
Tcur_3074PFAM: peptidase M48 Ste24p; KEGG: rso:RSc0941 integral membrane protease transmembrane protein. (431 aa)
Tcur_3231Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (264 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (389 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (415 aa)
Tcur_3474TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: bur:Bcep18194_B1439 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (384 aa)
Tcur_3495KEGG: abo:ABO_0253 acetyl-CoA acyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
Tcur_3654KEGG: eba:p2A394 DitO-like thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
Tcur_3890KEGG: reu:Reut_A1348 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
Tcur_3981KEGG: dal:Dalk_4048 propanoyl-CoA C-acyltransferase. (385 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (242 aa)
Tcur_4404Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: xca:xccb100_1425 octaprenyl-diphosphate synthase, probable; Belongs to the FPP/GGPP synthase family. (331 aa)
Tcur_4616KEGG: mxa:MXAN_5135 acetyl-CoA acetyltransferase family protein; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
Your Current Organism:
Thermomonospora curvata
NCBI taxonomy Id: 471852
Other names: T. curvata DSM 43183, Thermomonospora curvata DSM 43183, Thermomonospora curvata IFO 15933, Thermomonospora curvata JCM 3096, Thermomonospora curvata NBRC 15933, Thermomonospora curvata str. DSM 43183, Thermomonospora curvata strain DSM 43183
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