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Bcav_4201 Bcav_4201 Bcav_0064 Bcav_0064 Bcav_0099 Bcav_0099 Bcav_0117 Bcav_0117 Bcav_0119 Bcav_0119 Bcav_0131 Bcav_0131 Bcav_0225 Bcav_0225 Bcav_0232 Bcav_0232 Bcav_0342 Bcav_0342 Bcav_0378 Bcav_0378 Bcav_0385 Bcav_0385 Bcav_0402 Bcav_0402 Bcav_0497 Bcav_0497 upp upp Bcav_0603 Bcav_0603 acsA acsA tmk tmk Bcav_0671 Bcav_0671 Bcav_0701 Bcav_0701 folE folE ispD ispD ispF ispF Bcav_0844 Bcav_0844 Bcav_0905 Bcav_0905 Bcav_0958 Bcav_0958 idi idi ispE ispE glmU glmU prs prs Bcav_0994 Bcav_0994 ispH ispH Bcav_1150 Bcav_1150 Bcav_1154 Bcav_1154 purK purK purE purE Bcav_1185 Bcav_1185 Bcav_1205 Bcav_1205 Bcav_1210 Bcav_1210 Bcav_1229 Bcav_1229 atpB atpB atpE atpE atpF atpF atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC Bcav_1380 Bcav_1380 Bcav_1510 Bcav_1510 Bcav_1589 Bcav_1589 gpsA gpsA thiL thiL coaD coaD nadD nadD Bcav_1646 Bcav_1646 Bcav_1678 Bcav_1678 moaA moaA Bcav_1691 Bcav_1691 Bcav_1693 Bcav_1693 moaC moaC Bcav_1715 Bcav_1715 pyrE pyrE nadE nadE Bcav_1877 Bcav_1877 Bcav_1904 Bcav_1904 Bcav_1932 Bcav_1932 dut dut Bcav_1951 Bcav_1951 dxs dxs Bcav_1981 Bcav_1981 pdxS pdxS pdxT pdxT apt apt Bcav_1999 Bcav_1999 pyrB pyrB pyrC pyrC Bcav_2036 Bcav_2036 carA carA carB carB pyrF pyrF gmk gmk Bcav_2044 Bcav_2044 Bcav_2062 Bcav_2062 Bcav_2071 Bcav_2071 Bcav_2106 Bcav_2106 Bcav_2149 Bcav_2149 cmk cmk Bcav_2186 Bcav_2186 coaE coaE Bcav_2296 Bcav_2296 Bcav_2328 Bcav_2328 pyrG pyrG Bcav_2354 Bcav_2354 nadK nadK Bcav_2365 Bcav_2365 Bcav_2394 Bcav_2394 Bcav_2456 Bcav_2456 Bcav_2457 Bcav_2457 Bcav_2473 Bcav_2473 Bcav_2486 Bcav_2486 ispG ispG dxr dxr Bcav_2503 Bcav_2503 pyrH pyrH ndk ndk Bcav_2578 Bcav_2578 Bcav_2742 Bcav_2742 Bcav_2774 Bcav_2774 Bcav_2775 Bcav_2775 nadA nadA Bcav_2792 Bcav_2792 Bcav_2808 Bcav_2808 Bcav_2809 Bcav_2809 thyA thyA Bcav_2926 Bcav_2926 Bcav_2936 Bcav_2936 folD folD purU purU purH purH purN purN guaA guaA Bcav_3044 Bcav_3044 Bcav_3048 Bcav_3048 ackA ackA Bcav_3053 Bcav_3053 guaB guaB Bcav_3099 Bcav_3099 coaA coaA Bcav_3101 Bcav_3101 adk adk araA araA araB araB Bcav_3297 Bcav_3297 purM purM purF purF Bcav_3535 Bcav_3535 purL purL purQ purQ purS purS purC purC purD purD Bcav_3610 Bcav_3610 Bcav_3611 Bcav_3611 Bcav_3616 Bcav_3616 purA purA pyrE-2 pyrE-2 Bcav_3737 Bcav_3737 Bcav_3738 Bcav_3738 Bcav_3790 Bcav_3790 dcd dcd Bcav_3967 Bcav_3967 Bcav_3975 Bcav_3975 Bcav_3976 Bcav_3976 Bcav_4039 Bcav_4039 Bcav_4170 Bcav_4170
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Bcav_4201PFAM: Myo-inositol-1-phosphate synthase; TIGRFAM: inositol 1-phosphate synthase, Actinobacterial type. (357 aa)
Bcav_0064Conserved hypothetical protein. (175 aa)
Bcav_0099Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (326 aa)
Bcav_0117PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (162 aa)
Bcav_0119Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain. (171 aa)
Bcav_0131PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase. (318 aa)
Bcav_0225Adenylate/guanylate cyclase with integral membrane sensor; PFAM: Adenylate and Guanylate cyclase catalytic domain; HAMP domain. (695 aa)
Bcav_0232Conserved hypothetical protein. (417 aa)
Bcav_0342Protein of unknown function DUF201; PFAM: ATP-grasp domain. (302 aa)
Bcav_0378PFAM: Diacylglycerol kinase catalytic domain. (374 aa)
Bcav_0385PFAM: Adenylate and Guanylate cyclase catalytic domain. (1198 aa)
Bcav_0402Hypothetical protein. (264 aa)
Bcav_0497Pyridoxal 5'-phosphate synthase; PFAM: Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Pyridoxamine 5'-phosphate oxidase. (223 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)
Bcav_0603Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase. (308 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (667 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (210 aa)
Bcav_0671PFAM: NUDIX domain. (153 aa)
Bcav_0701PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
folEPFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. (200 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (243 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
Bcav_0844PFAM: Glutamine amidotransferase class-I. (253 aa)
Bcav_0905Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (404 aa)
Bcav_0958PFAM: Isochorismatase family. (194 aa)
idiIsopentenyl-diphosphate delta-isomerase, type 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (191 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (309 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (522 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
Bcav_0994PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (261 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (331 aa)
Bcav_1150PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. (277 aa)
Bcav_1154PFAM: Adenylate and Guanylate cyclase catalytic domain. (364 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (378 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (183 aa)
Bcav_1185Acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase. (253 aa)
Bcav_1205TIGRFAM: conserved hypothetical protein TIGR03089. (252 aa)
Bcav_1210Transferase hexapeptide repeat containing protein. (135 aa)
Bcav_1229Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (411 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (282 aa)
atpEATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa)
atpFATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (200 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (271 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (544 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (297 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (491 aa)
atpCH+transporting two-sector ATPase delta/epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (109 aa)
Bcav_1380Conserved hypothetical protein. (164 aa)
Bcav_1510PFAM: FGGY family of carbohydrate kinases, C-terminal domain; FGGY family of carbohydrate kinases, N-terminal domain; TIGRFAM: L-ribulokinase; FGGY-family pentulose kinase. (524 aa)
Bcav_1589PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (268 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (346 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (168 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (214 aa)
Bcav_1646Glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: 3-demethylubiquinone-9 3-methyltransferase. (138 aa)
Bcav_1678Opine dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain. (370 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (360 aa)
Bcav_1691thiamineS protein; PFAM: ThiS family. (103 aa)
Bcav_1693PFAM: MoaE protein. (142 aa)
moaCMolybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (359 aa)
Bcav_1715Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase. (577 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (185 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (547 aa)
Bcav_1877Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (344 aa)
Bcav_1904PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (264 aa)
Bcav_1932PFAM: Thymidine kinase. (229 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (177 aa)
Bcav_1951PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein; inosine-5'-monophosphate dehydrogenase. (485 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (643 aa)
Bcav_1981PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (205 aa)
pdxSPyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (307 aa)
pdxTSNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (200 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (183 aa)
Bcav_1999(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (790 aa)
pyrBPFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (332 aa)
pyrCDihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (432 aa)
Bcav_2036Conserved hypothetical protein. (187 aa)
carAPFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (405 aa)
carBPFAM: MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit. (1109 aa)
pyrFPFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. (282 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (180 aa)
Bcav_2044Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (421 aa)
Bcav_2062PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: conserved protein of unknown function cotranscribed with Bmr (bmrU). (321 aa)
Bcav_2071PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (136 aa)
Bcav_2106CDP-diacylglycerol-phosphatidylglycerolphosphati dyltransferase. (138 aa)
Bcav_2149PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases. (253 aa)
cmkPFAM: Cytidylate kinase; Shikimate kinase; TIGRFAM: cytidylate kinase. (246 aa)
Bcav_2186Uridine kinase. (223 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (354 aa)
Bcav_2296PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (184 aa)
Bcav_2328PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (134 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (567 aa)
Bcav_2354PFAM: Thiamin pyrophosphokinase, catalytic domain. (407 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (297 aa)
Bcav_2365Conserved hypothetical protein. (196 aa)
Bcav_2394ATP-dependent DNA helicase, RecQ family; PFAM: Phosphoribosyl transferase domain; Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family. (756 aa)
Bcav_2456CinA domain protein; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain; Belongs to the CinA family. (166 aa)
Bcav_2457PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (213 aa)
Bcav_2473PFAM: Diacylglycerol kinase catalytic domain. (371 aa)
Bcav_2486Riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (333 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (392 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa)
Bcav_2503PFAM: Cytidylyltransferase family; Belongs to the CDS family. (403 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (265 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
Bcav_2578Dihydropyrimidinase; PFAM: Amidohydrolase family; TIGRFAM: D-hydantoinase. (478 aa)
Bcav_2742Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (442 aa)
Bcav_2774Nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (285 aa)
Bcav_2775L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (519 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (425 aa)
Bcav_2792PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (176 aa)
Bcav_2808Molybdopterin-guanine dinucleotide biosynthesis protein. (206 aa)
Bcav_2809Molybdopterin-guanine dinucleotide biosynthesis protein. (97 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (275 aa)
Bcav_2926Putative integral membrane protein. (394 aa)
Bcav_2936PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase. (372 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (280 aa)
purHPFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (538 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (211 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (515 aa)
Bcav_3044Conserved hypothetical protein. (125 aa)
Bcav_3048Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (701 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (407 aa)
Bcav_3053PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: IMP dehydrogenase family protein. (374 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (505 aa)
Bcav_3099Transcriptional regulator, SARP family; PFAM: Transcriptional regulatory protein, C terminal; NB-ARC domain; Bacterial transcriptional activator domain. (910 aa)
coaATIGRFAM: pantothenate kinase, bacterial type. (345 aa)
Bcav_3101Transcriptional regulator, SARP family; PFAM: Transcriptional regulatory protein, C terminal; NB-ARC domain; Bacterial transcriptional activator domain. (910 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (192 aa)
araAL-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (515 aa)
araBL-ribulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: L-ribulokinase. (598 aa)
Bcav_3297ATP-binding protein. (231 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, C-terminal domain; AIR synthase related protein, N-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. (370 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (517 aa)
Bcav_3535Protein of unknown function UPF0157; PFAM: Uncharacterised protein family (UPF0157). (204 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (775 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (237 aa)
purSPhosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (97 aa)
purCPFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (307 aa)
purDPhosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. (433 aa)
Bcav_3610PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (130 aa)
Bcav_3611Putative fructose transport system kinase. (208 aa)
Bcav_3616L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (476 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
pyrE-2Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (188 aa)
Bcav_3737PFAM: Acyltransferase. (193 aa)
Bcav_3738CDP-alcohol phosphatidyltransferase. (259 aa)
Bcav_3790Pyridoxamine 5'-phosphate oxidase-related protein FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase. (204 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (192 aa)
Bcav_3967PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit. (411 aa)
Bcav_3975PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (173 aa)
Bcav_3976PFAM: Adenylosuccinate lyase C-terminal; Lyase; TIGRFAM: adenylosuccinate lyase. (483 aa)
Bcav_4039Protein of unknown function UPF0157; PFAM: Uncharacterised protein family (UPF0157). (191 aa)
Bcav_4170Conserved hypothetical protein. (222 aa)
Your Current Organism:
Beutenbergia cavernae
NCBI taxonomy Id: 471853
Other names: B. cavernae DSM 12333, Beutenbergia cavernae DSM 12333, Beutenbergia cavernae str. DSM 12333, Beutenbergia cavernae strain DSM 12333
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