STRINGSTRING
purL purL pyrE pyrE surE surE surE-2 surE-2 Dfer_1068 Dfer_1068 folD folD purA purA Dfer_2476 Dfer_2476 purN purN pyrB pyrB Dfer_2676 Dfer_2676 guaA guaA Dfer_2966 Dfer_2966 purH purH pyrD pyrD Dfer_3540 Dfer_3540 purD purD Dfer_3692 Dfer_3692 Dfer_3743 Dfer_3743 gmk gmk Dfer_3881 Dfer_3881 Dfer_4043 Dfer_4043 Dfer_4180 Dfer_4180 carA carA Dfer_4379 Dfer_4379 tdk tdk guaB guaB Dfer_4447 Dfer_4447 Dfer_4467 Dfer_4467 Dfer_4546 Dfer_4546 purA-2 purA-2 Dfer_4657 Dfer_4657 Dfer_4675 Dfer_4675 purC purC purE purE purK purK
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1221 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa)
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (244 aa)
surE-2Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (255 aa)
Dfer_1068PFAM: CMP/dCMP deaminase zinc-binding; KEGG: chu:CHU_2215 cytidine/deoxycytidylate deaminase (dCMP deaminase). (164 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (392 aa)
Dfer_2476TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl- phosphate synthetase large chain domain protein; KEGG: chu:CHU_3278 carbamoyl-phosphate synthase large subunit. (947 aa)
purNFormyl transferase domain protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (189 aa)
pyrBTIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: chu:CHU_0084 aspartate carbamoyltransferase, catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa)
Dfer_2676PFAM: phosphoribosyltransferase; KEGG: chu:CHU_0083 uracil phosphoribosyltransferase; pyrimidine operon attenuation protein. (180 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (509 aa)
Dfer_2966TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: chu:CHU_2698 orotidine 5' phosphate decarboxylase. (274 aa)
purHIMP cyclohydrolase; KEGG: chu:CHU_3309 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region. (511 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (343 aa)
Dfer_3540KEGG: fjo:Fjoh_5015 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (451 aa)
purDKEGG: chu:CHU_0296 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. (429 aa)
Dfer_3692Allantoinase; PFAM: amidohydrolase; KEGG: chu:CHU_1007 dihydroorotase. (453 aa)
Dfer_3743KEGG: bvu:BVU_1681 putative hypoxanthine guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (189 aa)
Dfer_3881KEGG: fps:FP2471 uracil phosphoribosyltransferase. (214 aa)
Dfer_4043Amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; KEGG: chu:CHU_2612 amidophosphoribosyltransferase. (630 aa)
Dfer_4180Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; KEGG: bth:BT_4211 putative phosphoribosylformylglycinamidine cyclo-ligase. (388 aa)
carATIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl- phosphate synthase small chain; KEGG: chu:CHU_3134 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (368 aa)
Dfer_4379Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (223 aa)
tdkPFAM: thymidine kinase; KEGG: sru:SRU_2559 thymidine kinase. (201 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
Dfer_4447TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: gfo:GFO_0764 nucleoside triphosphate pyrophosphohydrolase. (276 aa)
Dfer_4467TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: chu:CHU_1793 dihydroorotase. (427 aa)
Dfer_4546PFAM: phosphoribulokinase/uridine kinase; KEGG: chu:CHU_0115 uridine kinase; Belongs to the uridine kinase family. (217 aa)
purA-2Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
Dfer_4657PFAM: 5 nucleotidase deoxy cytosolic type C; KEGG: fjo:Fjoh_4859 5 nucleotidase, deoxy, cytosolic type C. (177 aa)
Dfer_4675PFAM: phosphoribosyltransferase; KEGG: chu:CHU_0488 uracil phosphoribosyltransferase/pyrimidine operon attenuation protein. (172 aa)
purCPFAM: SAICAR synthetase; KEGG: chu:CHU_1912 phosphoribosylaminoimidazole- succinocarboxamide synthase. (311 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
Your Current Organism:
Dyadobacter fermentans
NCBI taxonomy Id: 471854
Other names: D. fermentans DSM 18053, Dyadobacter fermentans DSM 18053, Dyadobacter fermentans str. DSM 18053, Dyadobacter fermentans strain DSM 18053
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