STRINGSTRING
ACU95355.1 ACU95355.1 proC proC ACU95413.1 ACU95413.1 ACU95414.1 ACU95414.1 ACU95438.1 ACU95438.1 sucC sucC sucD sucD ACU95580.1 ACU95580.1 ACU95609.1 ACU95609.1 ACU95610.1 ACU95610.1 ACU95611.1 ACU95611.1 ACU95612.1 ACU95612.1 ACU95812.1 ACU95812.1 ACU95816.1 ACU95816.1 ACU95926.1 ACU95926.1 ACU95983.1 ACU95983.1 ACU96022.1 ACU96022.1 ACU96065.1 ACU96065.1 ACU96088.1 ACU96088.1 ACU96105.1 ACU96105.1 ACU96106.1 ACU96106.1 ACU96158.1 ACU96158.1 ACU96232.1 ACU96232.1 proB proB ACU96458.1 ACU96458.1 ACU96482.1 ACU96482.1 ACU96985.1 ACU96985.1 mdh mdh ACU97147.1 ACU97147.1 ACU97148.1 ACU97148.1 ACU97149.1 ACU97149.1 ACU97151.1 ACU97151.1 ACU97250.1 ACU97250.1 ACU97257.1 ACU97257.1 ACU97363.1 ACU97363.1 ACU97390.1 ACU97390.1 ACU97443.1 ACU97443.1 ACU97466.1 ACU97466.1 ACU97755.1 ACU97755.1 ACU97756.1 ACU97756.1 ACU97784.1 ACU97784.1 ACU97785.1 ACU97785.1 ACU97816.1 ACU97816.1 ACU97817.1 ACU97817.1 ACU97842.1 ACU97842.1 ACU97993.1 ACU97993.1 ACU97994.1 ACU97994.1 ACU98033.1 ACU98033.1 ACU98038.1 ACU98038.1 ACU98055.1 ACU98055.1 fumC fumC ACU98231.1 ACU98231.1 ACU98324.1 ACU98324.1 ACU98346.1 ACU98346.1 ACU98385.1 ACU98385.1 ACU98647.1 ACU98647.1 ACU98828.1 ACU98828.1 ACU98829.1 ACU98829.1 ACU98830.1 ACU98830.1 pckG pckG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACU95355.1PFAM: Proline dehydrogenase. (308 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
ACU95413.12-oxoacid:ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (354 aa)
ACU95414.12-oxoacid:ferredoxin oxidoreductase, alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain. (644 aa)
ACU95438.1PFAM: Aminotransferase class I and II. (411 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
ACU95580.1PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, eukaryotic type; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)
ACU95609.1TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (262 aa)
ACU95610.1PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgroup; succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup. (595 aa)
ACU95611.1PFAM: Succinate dehydrogenase cytochrome b subunit. (138 aa)
ACU95612.1PFAM: Succinate dehydrogenase cytochrome b subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit. (116 aa)
ACU95812.1PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I. (447 aa)
ACU95816.1PFAM: Glutamine synthetase, beta-Grasp domain; Glutamine synthetase, catalytic domain; TIGRFAM: glutamine synthetase, type I. (474 aa)
ACU95926.1Predicted amidohydrolase; PFAM: Carbon-nitrogen hydrolase. (280 aa)
ACU95983.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1127 aa)
ACU96022.1PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. (521 aa)
ACU96065.1Mycothione reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: mycothione reductase. (466 aa)
ACU96088.1Pyruvate dehydrogenase E1 component, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (938 aa)
ACU96105.12-oxoglutarate dehydrogenase E2 component; PFAM: e3 binding domain; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component). (598 aa)
ACU96106.1Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (457 aa)
ACU96158.1Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (465 aa)
ACU96232.1PFAM: Bacterial NAD-glutamate dehydrogenase. (1643 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa)
ACU96458.1Pyruvate dehydrogenase complex, dehydrogenase (E1) component; PFAM: Transketolase, C-terminal domain. (770 aa)
ACU96482.1PFAM: Isocitrate/isopropylmalate dehydrogenase. (356 aa)
ACU96985.1Predicted amidohydrolase; PFAM: Carbon-nitrogen hydrolase. (331 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
ACU97147.1Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit; PFAM: Dehydrogenase E1 component. (324 aa)
ACU97148.1Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain. (348 aa)
ACU97149.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: Biotin-requiring enzyme. (77 aa)
ACU97151.1PFAM: Acetamidase/Formamidase family. (401 aa)
ACU97250.1PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1. (942 aa)
ACU97257.1PFAM: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (393 aa)
ACU97363.1PFAM: Aminotransferase class I and II. (415 aa)
ACU97390.1PFAM: Aconitase family (aconitate hydratase); Aconitase C-terminal domain; TIGRFAM: aconitate hydratase, putative, Aquifex type. (649 aa)
ACU97443.1Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (567 aa)
ACU97466.1PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (537 aa)
ACU97755.1Succinate dehydrogenase subunit B; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (251 aa)
ACU97756.1PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain; Pyridine nucleotide-disulphide oxidoreductase. (638 aa)
ACU97784.1Glutamate synthase (NADH) small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit. (501 aa)
ACU97785.1Glutamate synthase (NADH) large subunit; PFAM: GXGXG motif; Glutamate synthase central domain; Conserved region in glutamate synthase; Glutamine amidotransferases class-II. (1527 aa)
ACU97816.1PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. (534 aa)
ACU97817.1PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase. (432 aa)
ACU97842.1TIGRFAM: gamma-glutamyl phosphate reductase. (413 aa)
ACU97993.1PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)
ACU97994.1PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa)
ACU98033.1PFAM: Dehydrogenase E1 component; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component. (1251 aa)
ACU98038.1PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (396 aa)
ACU98055.1PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; Belongs to the aldehyde dehydrogenase family. (534 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
ACU98231.1PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
ACU98324.1PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (437 aa)
ACU98346.1PFAM: Citrate synthase; Belongs to the citrate synthase family. (389 aa)
ACU98385.1PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (466 aa)
ACU98647.1PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (484 aa)
ACU98828.1PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit. (376 aa)
ACU98829.1Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain. (345 aa)
ACU98830.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: Biotin-requiring enzyme; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain. (473 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (608 aa)
Your Current Organism:
Saccharomonospora viridis
NCBI taxonomy Id: 471857
Other names: S. viridis DSM 43017, Saccharomonospora viridis ATCC 15386, Saccharomonospora viridis DSM 43017, Saccharomonospora viridis NCIB 9602, Saccharomonospora viridis NRRL B-3044, Saccharomonospora viridis str. DSM 43017, Saccharomonospora viridis strain DSM 43017
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.