STRINGSTRING
HA41_08540 HA41_08540 HA41_08545 HA41_08545 fadE fadE proB proB proA proA GCA_001743465_00070 GCA_001743465_00070 proC proC HA41_17650 HA41_17650 HA41_03175 HA41_03175 GCA_001743465_00230 GCA_001743465_00230 asnB asnB HA41_03775 HA41_03775 HA41_03780 HA41_03780 HA41_03785 HA41_03785 HA41_03790 HA41_03790 HA41_03795 HA41_03795 HA41_03800 HA41_03800 sucC sucC sucD sucD dld dld HA41_01935 HA41_01935 HA41_01755 HA41_01755 GCA_001743465_00569 GCA_001743465_00569 HA41_18705 HA41_18705 HA41_08215 HA41_08215 argD argD astA astA astD astD astB astB astE astE GCA_001743465_00823 GCA_001743465_00823 HA41_07755 HA41_07755 GCA_001743465_00866 GCA_001743465_00866 fumC fumC HA41_06360 HA41_06360 leuA leuA GCA_001743465_00971 GCA_001743465_00971 HA41_06235 HA41_06235 HA41_02900 HA41_02900 GCA_001743465_01100 GCA_001743465_01100 HA41_02740 HA41_02740 HA41_15735 HA41_15735 HA41_15730 HA41_15730 ilvE ilvE ilvD ilvD GCA_001743465_01162 GCA_001743465_01162 ilvC ilvC HA41_14930 HA41_14930 HA41_15105 HA41_15105 HA41_00380 HA41_00380 GCA_001743465_01334 GCA_001743465_01334 HA41_00800 HA41_00800 HA41_08400 HA41_08400 ghrA ghrA HA41_12200 HA41_12200 GCA_001743465_01772 GCA_001743465_01772 GCA_001743465_01847 GCA_001743465_01847 argD-2 argD-2 GCA_001743465_01924 GCA_001743465_01924 HA41_19055 HA41_19055 HA41_19060 HA41_19060 HA41_19105 HA41_19105 acs acs dapD dapD GCA_001743465_02193 GCA_001743465_02193 HA41_01570 HA41_01570 aceF aceF HA41_01545 HA41_01545 HA41_01370 HA41_01370 HA41_01365 HA41_01365 leuA-2 leuA-2 leuB leuB leuC leuC leuD leuD dapB dapB HA41_01130 HA41_01130 thrB thrB GCA_001743465_02285 GCA_001743465_02285 HA41_08055 HA41_08055 HA41_08060 HA41_08060 HA41_08065 HA41_08065 HA41_08070 HA41_08070 HA41_00165 HA41_00165 GCA_001743465_02545 GCA_001743465_02545 GCA_001743465_02662 GCA_001743465_02662 gabD gabD HA41_17125 HA41_17125 HA41_17130 HA41_17130 HA41_17135 HA41_17135 GCA_001743465_02706 GCA_001743465_02706 GCA_001743465_02710 GCA_001743465_02710 GCA_001743465_02713 GCA_001743465_02713 GCA_001743465_02714 GCA_001743465_02714 HA41_02545 HA41_02545 GCA_001743465_02878 GCA_001743465_02878 HA41_08985 HA41_08985 GCA_001743465_02961 GCA_001743465_02961 GCA_001743465_03079 GCA_001743465_03079 asd asd argE argE argC argC argB argB argG argG argH argH murI murI HA41_14985 HA41_14985 HA41_14990 HA41_14990 HA41_10715 HA41_10715 fadA fadA dapF dapF HA41_04840 HA41_04840 dapA dapA dapE dapE HA41_12900 HA41_12900 HA41_11885 HA41_11885 HA41_11890 HA41_11890 HA41_19565 HA41_19565 HA41_19665 HA41_19665 HA41_19765 HA41_19765 HA41_13835 HA41_13835 HA41_17725 HA41_17725 HA41_11250 HA41_11250 lysA lysA argA argA maeA maeA HA41_04090 HA41_04090 ackA ackA HA41_04125 HA41_04125 HA41_04225 HA41_04225 GCA_001743465_04712 GCA_001743465_04712 fadI fadI gabD-2 gabD-2 argR argR mdh mdh HA41_09465 HA41_09465
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HA41_08540Unannotated protein. (255 aa)
HA41_08545Unannotated protein. (386 aa)
fadEUnannotated protein. (817 aa)
proBUnannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)
proAUnannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa)
GCA_001743465_00070Unannotated protein. (395 aa)
proCUnannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
HA41_17650Unannotated protein. (419 aa)
HA41_03175Unannotated protein. (362 aa)
GCA_001743465_00230Unannotated protein. (436 aa)
asnBUnannotated protein. (555 aa)
HA41_03775Unannotated protein; Belongs to the citrate synthase family. (427 aa)
HA41_03780Unannotated protein. (129 aa)
HA41_03785Unannotated protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
HA41_03790Unannotated protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (569 aa)
HA41_03795Unannotated protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
HA41_03800Unannotated protein. (935 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
dldUnannotated protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (567 aa)
HA41_01935Unannotated protein. (319 aa)
HA41_01755Unannotated protein; Belongs to the TPP enzyme family. (573 aa)
GCA_001743465_00569Unannotated protein. (396 aa)
HA41_18705Unannotated protein; Belongs to the aldehyde dehydrogenase family. (457 aa)
HA41_08215Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa)
argDUnannotated protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (406 aa)
astAUnannotated protein; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. (343 aa)
astDUnannotated protein; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (489 aa)
astBUnannotated protein; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (442 aa)
astEUnannotated protein; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (331 aa)
GCA_001743465_00823Unannotated protein. (794 aa)
HA41_07755Unannotated protein. (1017 aa)
GCA_001743465_00866Unannotated protein. (174 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
HA41_06360Unannotated protein. (287 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (572 aa)
GCA_001743465_00971Unannotated protein. (565 aa)
HA41_06235Unannotated protein; Belongs to the DapA family. (297 aa)
HA41_02900Unannotated protein; Belongs to the aldehyde dehydrogenase family. (478 aa)
GCA_001743465_01100Unannotated protein. (388 aa)
HA41_02740Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
HA41_15735Unannotated protein. (548 aa)
HA41_15730Unannotated protein. (85 aa)
ilvEUnannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (616 aa)
GCA_001743465_01162Unannotated protein. (515 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa)
HA41_14930Unannotated protein. (271 aa)
HA41_15105Unannotated protein. (501 aa)
HA41_00380Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
GCA_001743465_01334Unannotated protein. (306 aa)
HA41_00800Unannotated protein. (392 aa)
HA41_08400Unannotated protein. (416 aa)
ghrAUnannotated protein. (313 aa)
HA41_12200Unannotated protein. (469 aa)
GCA_001743465_01772Unannotated protein. (424 aa)
GCA_001743465_01847Unannotated protein. (252 aa)
argD-2Unannotated protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (406 aa)
GCA_001743465_01924Unannotated protein. (539 aa)
HA41_19055Unannotated protein; Belongs to the malate synthase family. (532 aa)
HA41_19060Unannotated protein. (433 aa)
HA41_19105Unannotated protein; Belongs to the aspartokinase family. (450 aa)
acsUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates [...] (651 aa)
dapDUnannotated protein; Belongs to the transferase hexapeptide repeat family. (274 aa)
GCA_001743465_02193Unannotated protein. (294 aa)
HA41_01570Unannotated protein; Belongs to the aconitase/IPM isomerase family. (865 aa)
aceFUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (633 aa)
HA41_01545Unannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)
HA41_01370Unannotated protein. (163 aa)
HA41_01365Unannotated protein. (574 aa)
leuA-2Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (520 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
dapBUnannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (271 aa)
HA41_01130Unannotated protein. (427 aa)
thrBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)
GCA_001743465_02285Unannotated protein. (820 aa)
HA41_08055Unannotated protein. (425 aa)
HA41_08060Unannotated protein. (185 aa)
HA41_08065Unannotated protein. (255 aa)
HA41_08070Unannotated protein; Belongs to the glutamine synthetase family. (471 aa)
HA41_00165Unannotated protein. (456 aa)
GCA_001743465_02545Unannotated protein. (45 aa)
GCA_001743465_02662Unannotated protein. (428 aa)
gabDUnannotated protein; Belongs to the aldehyde dehydrogenase family. (485 aa)
HA41_17125Unannotated protein; Belongs to the aldehyde dehydrogenase family. (489 aa)
HA41_17130Unannotated protein. (222 aa)
HA41_17135Unannotated protein. (425 aa)
GCA_001743465_02706Unannotated protein. (925 aa)
GCA_001743465_02710Unannotated protein. (505 aa)
GCA_001743465_02713Unannotated protein. (488 aa)
GCA_001743465_02714Unannotated protein. (460 aa)
HA41_02545Unannotated protein. (288 aa)
GCA_001743465_02878Unannotated protein. (893 aa)
HA41_08985Unannotated protein. (337 aa)
GCA_001743465_02961Unannotated protein. (569 aa)
GCA_001743465_03079Unannotated protein. (1315 aa)
asdUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (369 aa)
argEUnannotated protein. (382 aa)
argCUnannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa)
argBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (258 aa)
argGUnannotated protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
argHUnannotated protein. (457 aa)
murIUnannotated protein; Provides the (R)-glutamate required for cell wall biosynthesis. (283 aa)
HA41_14985Unannotated protein; Belongs to the alpha-acetolactate decarboxylase family. (260 aa)
HA41_14990Unannotated protein; Belongs to the TPP enzyme family. (559 aa)
HA41_10715Unannotated protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (727 aa)
fadAUnannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa)
dapFUnannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa)
HA41_04840Unannotated protein. (416 aa)
dapAUnannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
dapEUnannotated protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa)
HA41_12900Unannotated protein; Belongs to the ArsC family. (122 aa)
HA41_11885Unannotated protein. (174 aa)
HA41_11890Unannotated protein. (411 aa)
HA41_19565Unannotated protein. (356 aa)
HA41_19665Unannotated protein. (523 aa)
HA41_19765Unannotated protein. (1843 aa)
HA41_13835Unannotated protein. (169 aa)
HA41_17725Unannotated protein. (327 aa)
HA41_11250Unannotated protein. (88 aa)
lysAUnannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa)
argAUnannotated protein; Belongs to the acetyltransferase family. ArgA subfamily. (446 aa)
maeAUnannotated protein. (565 aa)
HA41_04090Unannotated protein. (405 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
HA41_04125Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa)
HA41_04225Unannotated protein; Belongs to the aspartate-semialdehyde dehydrogenase family. (335 aa)
GCA_001743465_04712Unannotated protein. (698 aa)
fadIUnannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa)
gabD-2Unannotated protein; Belongs to the aldehyde dehydrogenase family. (483 aa)
argRUnannotated protein; Regulates arginine biosynthesis genes. (156 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
HA41_09465Unannotated protein. (542 aa)
Your Current Organism:
Pantoea conspicua
NCBI taxonomy Id: 472705
Other names: CDC 3527-71, DSM 24241, LMG 24534, LMG:24534, P. conspicua, Pantoea conspicua Brady et al. 2010, Pantoea sp. LMG 24534, Pantoea sp. R-35496, strain BD 805
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