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| | fbp | PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: noc:Noc_0021 fructose-1,6-bisphosphatase. (335 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (517 aa) |
| | Nhal_0099 | 2-oxoglutarate dehydrogenase, E1 subunit; KEGG: noc:Noc_0111 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component. (943 aa) |
| | Nhal_0100 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (431 aa) |
| | Nhal_0101 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: noc:Noc_0113 dihydrolipoamide dehydrogenase. (477 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa) |
| | Nhal_0232 | PFAM: Aldehyde Dehydrogenase; KEGG: noc:Noc_0391 aldehyde dehydrogenase. (454 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa) |
| | pfp | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (421 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (220 aa) |
| | Nhal_0580 | KEGG: noc:Noc_2628 methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family. (386 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa) |
| | Nhal_0655 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: noc:Noc_2520 acetolactate synthase large subunit biosynthetic type. (582 aa) |
| | Nhal_0656 | KEGG: noc:Noc_2519 acetolactate synthase small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein. (164 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (511 aa) |
| | Nhal_0663 | PFAM: NUDIX hydrolase; KEGG: noc:Noc_2512 NUDIX hydrolase; Belongs to the Nudix hydrolase family. (174 aa) |
| | Nhal_0686 | KEGG: noc:Noc_2492 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa) |
| | Nhal_0706 | TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: noc:Noc_2473 succinate dehydrogenase, cytochrome b subunit. (125 aa) |
| | Nhal_0707 | TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: noc:Noc_2472 succinate dehydrogenase, hydrophobic membrane anchor protein. (109 aa) |
| | Nhal_0708 | TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; succinate dehydrogenase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: noc:Noc_2471 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (587 aa) |
| | Nhal_0709 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: noc:Noc_2470 succinate dehydrogenase/fumarate reductase iron-sulfur protein. (231 aa) |
| | Nhal_0746 | Phosphoketolase; PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: mca:MCA1587 putative phosphoketolase. (796 aa) |
| | Nhal_0797 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: noc:Noc_1769 short-chain dehydrogenase/reductase SDR. (259 aa) |
| | Nhal_1066 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: noc:Noc_1555 acyl-CoA dehydrogenase. (639 aa) |
| | Nhal_1075 | PFAM: acylphosphatase; KEGG: noc:Noc_0888 acylphosphatase. (95 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: noc:Noc_0903 glucose-6-phosphate isomerase; Belongs to the GPI family. (556 aa) |
| | prpB | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (296 aa) |
| | Nhal_1207 | KEGG: noc:Noc_2208 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family. (374 aa) |
| | Nhal_1208 | KEGG: noc:Noc_2207 2-methylcitrate dehydratase; TIGRFAM: 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein. (483 aa) |
| | Nhal_1211 | Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: noc:Noc_1433 branched-chain alpha-keto acid dehydrogenase subunit E2. (374 aa) |
| | Nhal_1212 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: noc:Noc_1434 transketolase. (326 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (358 aa) |
| | Nhal_1214 | PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; KEGG: noc:Noc_1436 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (371 aa) |
| | Nhal_1350 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: aeh:Mlg_2089 fructose-bisphosphate aldolase. (349 aa) |
| | Nhal_1352 | Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; KEGG: noc:Noc_1582 malic enzyme. (779 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (244 aa) |
| | Nhal_1378 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pol:Bpro_4767 short-chain dehydrogenase/reductase SDR. (255 aa) |
| | Nhal_1398 | PFAM: O-methyltransferase family 3; KEGG: noc:Noc_1264 O-methyltransferase family protein. (220 aa) |
| | Nhal_1401 | PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: noc:Noc_1266 acetolactate synthase large subunit; Belongs to the TPP enzyme family. (606 aa) |
| | Nhal_1402 | KEGG: noc:Noc_1267 hypothetical protein. (266 aa) |
| | Nhal_1431 | PFAM: Aldehyde Dehydrogenase; KEGG: noc:Noc_1710 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (513 aa) |
| | Nhal_1445 | PFAM: carbohydrate kinase FGGY; KEGG: noc:Noc_1697 carbohydrate kinase, FGGY. (442 aa) |
| | Nhal_1482 | TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: noc:Noc_2707 aconitate hydratase. (644 aa) |
| | Nhal_1563 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (794 aa) |
| | Nhal_1577 | Phosphonopyruvate decarboxylase-related protein; KEGG: sat:SYN_02641 cofactor-independent phosphoglycerate mutase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein. (411 aa) |
| | Nhal_1578 | TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: mxa:MXAN_2372 6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (312 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transketolase family. (981 aa) |
| | Nhal_1763 | PFAM: Aldehyde Dehydrogenase; KEGG: pag:PLES_52851 putative aldehyde dehydrogenase. (310 aa) |
| | Nhal_1873 | PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: noc:Noc_2077 6-phosphogluconate dehydrogenase, NAD-binding. (285 aa) |
| | Nhal_1912 | PFAM: Aldehyde Dehydrogenase; KEGG: dat:HRM2_11640 NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (463 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (362 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (286 aa) |
| | Nhal_2074 | KEGG: noc:Noc_1736 hypothetical protein. (728 aa) |
| | Nhal_2075 | PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: noc:Noc_1735 acyl-CoA dehydrogenase. (758 aa) |
| | Nhal_2076 | acetyl-CoA acetyltransferase; KEGG: noc:Noc_1734 3-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa) |
| | Nhal_2077 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: noc:Noc_1733 multifunctional fatty acid oxidation complex subunit alpha; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (746 aa) |
| | Nhal_2089 | TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; KEGG: pen:PSEEN5495 pyruvate carboxylase subunit B. (608 aa) |
| | Nhal_2090 | PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: tgr:Tgr7_1915 acetyl-CoA carboxylase, biotin carboxylase. (472 aa) |
| | Nhal_2091 | PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: noc:Noc_1719 phosphoglucomutase. (544 aa) |
| | pdhA-2 | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (367 aa) |
| | Nhal_2153 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: sfu:Sfum_2647 transketolase, central region. (326 aa) |
| | Nhal_2154 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: sfu:Sfum_2646 catalytic domain of components of various dehydrogenase complexes. (429 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (962 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa) |
| | Nhal_2282 | PFAM: NUDIX hydrolase; KEGG: noc:Noc_2420 ADP-ribose diphosphatase NudE. (193 aa) |
| | Nhal_2479 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: noc:Noc_0826 3-hydroxyacyl-CoA dehydrogenase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (672 aa) |
| | Nhal_2480 | KEGG: noc:Noc_0827 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa) |
| | ppc-2 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (932 aa) |
| | Nhal_2497 | PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; ArgK protein; KEGG: noc:Noc_1893 methylmalonyl-CoA mutase-like. (1137 aa) |
| | Nhal_2498 | KEGG: noc:Noc_1891 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa) |
| | Nhal_2499 | Methylcrotonoyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: noc:Noc_1890 propionyl-CoA carboxylase. (535 aa) |
| | Nhal_2500 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: noc:Noc_1889 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa) |
| | Nhal_2501 | PFAM: pyruvate carboxyltransferase; KEGG: noc:Noc_1888 pyruvate carboxyltransferase. (350 aa) |
| | Nhal_2509 | TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: noc:Noc_2047 acetoacetyl-CoA synthetase. (651 aa) |
| | Nhal_2510 | TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: noc:Noc_2046 zinc-containing alcohol dehydrogenase superfamily protein. (333 aa) |
| | Nhal_2539 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: noc:Noc_1378 isocitrate dehydrogenase NADP-dependent. (422 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (426 aa) |
| | acsA | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa) |
| | Nhal_2719 | PFAM: Beta-ketoacyl synthase; KEGG: noc:Noc_1777 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (412 aa) |
| | fabA | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa) |
| | pdhA-3 | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (342 aa) |
| | Nhal_2781 | Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa) |
| | Nhal_2782 | PFAM: catalytic domain of components of various dehydrogenase complexes; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: noc:Noc_2109 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzyme. (897 aa) |
| | Nhal_2787 | KEGG: noc:Noc_2103 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; TIGRFAM: aconitate hydratase 2; PFAM: Aconitase B, N-terminal; aconitate hydratase domain protein; Belongs to the aconitase/IPM isomerase family. (850 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (519 aa) |
| | Nhal_2849 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (480 aa) |
| | tal-2 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (376 aa) |
| | Nhal_2900 | 2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (891 aa) |
| | Nhal_2901 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: noc:Noc_1255 branched-chain alpha-keto acid dehydrogenase subunit E2. (441 aa) |
| | Nhal_2902 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: noc:Noc_1256 dihydrolipoamide dehydrogenase. (472 aa) |
| | Nhal_2948 | PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: noc:Noc_0965 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzyme. (469 aa) |
| | tal-3 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (369 aa) |
| | Nhal_2962 | KEGG: noc:Noc_0983 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase. (331 aa) |
| | Nhal_2972 | KEGG: noc:Noc_0990 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (492 aa) |
| | Nhal_3038 | 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; KEGG: bph:Bphy_6460 MmgE/PrpD family protein. (464 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (245 aa) |
| | glk | Glucokinase; KEGG: noc:Noc_1347 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (335 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (322 aa) |
| | Nhal_3116 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: noc:Noc_1666 malonyl CoA-acyl carrier protein transacylase. (313 aa) |
| | Nhal_3117 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) |
| | Nhal_3119 | TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase; KEGG: noc:Noc_1663 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (398 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (468 aa) |
| | Nhal_3249 | PFAM: catalytic domain of components of various dehydrogenase complexes; KEGG: nmu:Nmul_A0372 dehydrogenase catalytic domain-containing protein. (277 aa) |
| | ilvD | KEGG: noc:Noc_2001 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (623 aa) |
| | Nhal_3361 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: noc:Noc_2690 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (232 aa) |
| | Nhal_3411 | PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bur:Bcep18194_B3095 3-oxoacyl-[acyl-carrier-protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (237 aa) |
| | nnrD | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (496 aa) |
| | Nhal_3446 | Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa) |
| | Nhal_3447 | KEGG: noc:Noc_2805 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (488 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: noc:Noc_2806 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (392 aa) |
| | Nhal_3449 | KEGG: noc:Noc_2807 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa) |
| | Nhal_3450 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa) |
| | Nhal_3492 | PFAM: Aldehyde Dehydrogenase; KEGG: noc:Noc_2605 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa) |
| | Nhal_3560 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (148 aa) |
| | Nhal_3561 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) |
| | Nhal_3790 | PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: hypothetical protein. (270 aa) |
| | Nhal_3802 | Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; KEGG: noc:Noc_2994 phosphomannomutase. (832 aa) |
| | Nhal_3894 | PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: noc:Noc_0244 malate dehydrogenase. (437 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa) |
