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Nhal_1211 Nhal_1211 Nhal_2076 Nhal_2076 Nhal_2154 Nhal_2154 fabZ fabZ lpxA lpxA Nhal_2480 Nhal_2480 Nhal_2498 Nhal_2498 ectA ectA Nhal_2719 Nhal_2719 dapD dapD fabA fabA Nhal_2805 Nhal_2805 Nhal_2901 Nhal_2901 Nhal_2920 Nhal_2920 plsX plsX fabH fabH Nhal_3116 Nhal_3116 Nhal_3119 Nhal_3119 Nhal_3198 Nhal_3198 Nhal_3217 Nhal_3217 Nhal_3220 Nhal_3220 Nhal_3250 Nhal_3250 Nhal_3258 Nhal_3258 Nhal_3259 Nhal_3259 argA argA lpxD lpxD lnt lnt glmU glmU Nhal_0797 Nhal_0797 Nhal_0988 Nhal_0988 Nhal_1231 Nhal_1231 Nhal_1345 Nhal_1345 tmcA tmcA metAS metAS Nhal_1582 Nhal_1582 Nhal_1765 Nhal_1765 Nhal_1928 Nhal_1928 Nhal_2012 Nhal_2012 bioF bioF Nhal_0661 Nhal_0661 lipB lipB argJ argJ Nhal_0325 Nhal_0325 Nhal_0100 Nhal_0100 tsaD tsaD plsY plsY ffsA ffsA Nhal_0009 Nhal_0009
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Nhal_1211Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: noc:Noc_1433 branched-chain alpha-keto acid dehydrogenase subunit E2. (374 aa)
Nhal_2076acetyl-CoA acetyltransferase; KEGG: noc:Noc_1734 3-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
Nhal_2154PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: sfu:Sfum_2646 catalytic domain of components of various dehydrogenase complexes. (429 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (149 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (256 aa)
Nhal_2480KEGG: noc:Noc_0827 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
Nhal_2498KEGG: noc:Noc_1891 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
ectAL-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (162 aa)
Nhal_2719PFAM: Beta-ketoacyl synthase; KEGG: noc:Noc_1777 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (412 aa)
dapDTIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; KEGG: noc:Noc_2125 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (273 aa)
fabABeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa)
Nhal_2805KEGG: sfu:Sfum_2138 hypothetical protein. (130 aa)
Nhal_2901PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: noc:Noc_1255 branched-chain alpha-keto acid dehydrogenase subunit E2. (441 aa)
Nhal_2920KEGG: nmu:Nmul_A1535 hypothetical protein. (390 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (340 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (322 aa)
Nhal_3116TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: noc:Noc_1666 malonyl CoA-acyl carrier protein transacylase. (313 aa)
Nhal_3119TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase; KEGG: noc:Noc_1663 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (398 aa)
Nhal_3198KEGG: noc:Noc_1148 hypothetical protein. (259 aa)
Nhal_3217KEGG: rfr:Rfer_0693 hypothetical protein. (230 aa)
Nhal_3220KEGG: nmu:Nmul_A2517 hypothetical protein. (317 aa)
Nhal_3250KEGG: noc:Noc_1989 putative glycan acetyltransferase. (227 aa)
Nhal_3258KEGG: noc:Noc_1995 hypothetical protein. (249 aa)
Nhal_3259KEGG: noc:Noc_1996 hypothetical protein. (294 aa)
argAAmino-acid N-acetyltransferase; KEGG: noc:Noc_2013 N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: aspartate/glutamate/uridylate kinase; GCN5-related N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. (438 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (347 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (520 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (457 aa)
Nhal_0797PFAM: short-chain dehydrogenase/reductase SDR; KEGG: noc:Noc_1769 short-chain dehydrogenase/reductase SDR. (259 aa)
Nhal_0988PFAM: GCN5-related N-acetyltransferase; KEGG: dac:Daci_1863 GCN5-related N-acetyltransferase. (181 aa)
Nhal_1231acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (260 aa)
Nhal_1345KEGG: noc:Noc_1795 hypothetical protein. (676 aa)
tmcAProtein of unknown function DUF699 ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (746 aa)
metASHomoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (363 aa)
Nhal_1582PFAM: CoA-binding domain protein; GCN5-related N-acetyltransferase; ATP-grasp domain protein; KEGG: pol:Bpro_1205 CoA-binding. (895 aa)
Nhal_1765KEGG: nmu:Nmul_A1224 hypothetical protein. (304 aa)
Nhal_1928KEGG: noc:Noc_1647 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein. (269 aa)
Nhal_2012PFAM: CoA-binding domain protein; GCN5-related N-acetyltransferase; KEGG: nmu:Nmul_A1676 GCN5-related N-acetyltransferase. (890 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (387 aa)
Nhal_0661TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: noc:Noc_2514 ribosomal-protein-alanine acetyltransferase. (161 aa)
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (210 aa)
argJArginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (405 aa)
Nhal_0325KEGG: tgr:Tgr7_2736 putative hemolysin. (263 aa)
Nhal_01002-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (431 aa)
tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (335 aa)
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (201 aa)
ffsAFormylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family. (298 aa)
Nhal_0009KEGG: nmu:Nmul_A1535 hypothetical protein. (394 aa)
Your Current Organism:
Nitrosococcus halophilus
NCBI taxonomy Id: 472759
Other names: N. halophilus Nc 4, Nitrosococcus halophilus Nc 4, Nitrosococcus halophilus str. Nc 4, Nitrosococcus halophilus strain Nc 4
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