(65 nodes) Ligand binding domain of hormone receptors, and Regulation of lipid metabolism by PPARalpha network (Neogobius melanostomus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSNMLP00000000284	Progesterone receptor. (638 aa)
	ENSNMLP00000000586	annotation not available (595 aa)
	ENSNMLP00000001281	annotation not available (435 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (474 aa)
	ENSNMLP00000002135	Nuclear receptor subfamily 5, group A, member 2. (498 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (290 aa)
	RARA	Retinoic acid receptor alpha. (498 aa)
	ENSNMLP00000003737	annotation not available (676 aa)
	ENSNMLP00000004255	Nuclear receptor subfamily 4, group A, member 3. (533 aa)
	ENSNMLP00000004491	Transducin (beta)-like 1 X-linked receptor 1b. (516 aa)
	ENSNMLP00000004564	Protein arginine methyltransferase 1. (357 aa)
	ENSNMLP00000004647	annotation not available (639 aa)
	ENSNMLP00000005082	Nuclear receptor subfamily 1, group D, member 4b. (543 aa)
	ENSNMLP00000006482	Nuclear receptor subfamily 1, group H, member 4. (463 aa)
	ENSNMLP00000010062	annotation not available (306 aa)
	ENSNMLP00000010091	Estrogen-related receptor gamma a. (442 aa)
	ENSNMLP00000010412	Nuclear receptor subfamily 0, group B, member 2a. (254 aa)
	ENSNMLP00000010594	Nuclear receptor subfamily 1, group D, member 2a. (555 aa)
	ENSNMLP00000011401	Nuclear receptor subfamily 5, group A, member 5. (525 aa)
	ENSNMLP00000012989	annotation not available (408 aa)
	ENSNMLP00000013552	annotation not available (268 aa)
	ENSNMLP00000013908	Nuclear receptor subfamily 1, group H, member 5. (458 aa)
	ENSNMLP00000015222	Hepatocyte nuclear factor 4, gamma. (436 aa)
	ENSNMLP00000015532	annotation not available (464 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (446 aa)
	ENSNMLP00000016253	Estrogen receptor 2a. (586 aa)
	ENSNMLP00000016548	Lysine (K)-specific methyltransferase 2E. (450 aa)
	ESRRB	Estrogen related receptor beta. (459 aa)
	ENSNMLP00000016908	Sp1 transcription factor. (440 aa)
	NR5A1	Nuclear receptor subfamily 5 group A member 1. (428 aa)
	ENSNMLP00000018474	Nuclear receptor subfamily 1, group D, member 4a. (543 aa)
	ENSNMLP00000018997	Nuclear receptor subfamily 5, group A, member 1a. (476 aa)
	ENSNMLP00000021090	Nuclear receptor subfamily 1, group D, member 2b. (481 aa)
	ENSNMLP00000021751	Nuclear receptor subfamily 1, group I, member 2. (423 aa)
	ENSNMLP00000023407	Thyroid hormone receptor beta. (493 aa)
	ENSNMLP00000023649	annotation not available (446 aa)
	ENSNMLP00000025817	Estrogen-related receptor gamma b. (459 aa)
	ENSNMLP00000026594	annotation not available (96 aa)
	ENSNMLP00000027629	Low density lipoprotein receptor class A domain containing 4b. (262 aa)
	ENSNMLP00000028240	Peroxisome proliferator-activated receptor delta b. (508 aa)
	ENSNMLP00000028533	Transducin beta like 1 X-linked. (524 aa)
	GATA2	GATA binding protein 2. (452 aa)
	ENSNMLP00000029633	Nuclear receptor coactivator 3. (1140 aa)
	ENSNMLP00000030039	Vitamin D receptor b. (432 aa)
	ENSNMLP00000030120	Coactivator-associated arginine methyltransferase 1. (691 aa)
	ENSNMLP00000030136	Thyroid hormone receptor alpha b. (390 aa)
	RXRB	Retinoid X receptor beta. (471 aa)
	ENSNMLP00000031224	Forkhead box A3. (420 aa)
	ENSNMLP00000032486	annotation not available (232 aa)
	ENSNMLP00000033094	Nuclear receptor subfamily 4, group A, member 1. (559 aa)
	PPARG	Peroxisome proliferator activated receptor gamma. (550 aa)
	ENSNMLP00000033747	Vitamin D receptor. (436 aa)
	ENSNMLP00000034008	Estrogen receptor 1. (609 aa)
	ENSNMLP00000034318	Selenoprotein J. (327 aa)
	ENSNMLP00000036683	Nuclear receptor coactivator 1. (1403 aa)
	ENSNMLP00000037545	Nuclear respiratory factor 1. (488 aa)
	ENSNMLP00000037906	Estrogen-related receptor alpha. (429 aa)
	ENSNMLP00000039347	annotation not available (194 aa)
	ENSNMLP00000039348	annotation not available (499 aa)
	ENSNMLP00000042701	Peroxisome proliferator-activated receptor alpha a. (464 aa)
	THRA	Thyroid hormone receptor alpha. (437 aa)
	ENSNMLP00000043630	Nuclear receptor subfamily 4, group A, member 2a. (569 aa)
	ENSNMLP00000044377	annotation not available (566 aa)
	ENSNMLP00000044587	annotation not available (707 aa)
	ENSNMLP00000045074	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (890 aa)

Your Current Organism:

Neogobius melanostomus

NCBI taxonomy Id: 47308
Other names: Apollonia melanostoma, Apollonia melanostomus, Gobius melanostomus, N. melanostomus, round goby

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSNMLP00000000284	ENSNMLP00000002135	ENSNMLP00000000284	ENSNMLP00000002135	Progesterone receptor.	Nuclear receptor subfamily 5, group A, member 2.	0.479
ENSNMLP00000000284	ENSNMLP00000004647	ENSNMLP00000000284	ENSNMLP00000004647	Progesterone receptor.	annotation not available	0.899
ENSNMLP00000000284	ENSNMLP00000010062	ENSNMLP00000000284	ENSNMLP00000010062	Progesterone receptor.	annotation not available	0.757
ENSNMLP00000000284	ENSNMLP00000011401	ENSNMLP00000000284	ENSNMLP00000011401	Progesterone receptor.	Nuclear receptor subfamily 5, group A, member 5.	0.463
ENSNMLP00000000284	ENSNMLP00000013552	ENSNMLP00000000284	ENSNMLP00000013552	Progesterone receptor.	annotation not available	0.501
ENSNMLP00000000284	ENSNMLP00000015222	ENSNMLP00000000284	ENSNMLP00000015222	Progesterone receptor.	Hepatocyte nuclear factor 4, gamma.	0.403
ENSNMLP00000000284	ENSNMLP00000016253	ENSNMLP00000000284	ENSNMLP00000016253	Progesterone receptor.	Estrogen receptor 2a.	0.899
ENSNMLP00000000284	ENSNMLP00000018997	ENSNMLP00000000284	ENSNMLP00000018997	Progesterone receptor.	Nuclear receptor subfamily 5, group A, member 1a.	0.479
ENSNMLP00000000284	ENSNMLP00000026594	ENSNMLP00000000284	ENSNMLP00000026594	Progesterone receptor.	annotation not available	0.474
ENSNMLP00000000284	ENSNMLP00000029633	ENSNMLP00000000284	ENSNMLP00000029633	Progesterone receptor.	Nuclear receptor coactivator 3.	0.951
ENSNMLP00000000284	ENSNMLP00000032486	ENSNMLP00000000284	ENSNMLP00000032486	Progesterone receptor.	annotation not available	0.474
ENSNMLP00000000284	ENSNMLP00000034008	ENSNMLP00000000284	ENSNMLP00000034008	Progesterone receptor.	Estrogen receptor 1.	0.899
ENSNMLP00000000284	ENSNMLP00000034318	ENSNMLP00000000284	ENSNMLP00000034318	Progesterone receptor.	Selenoprotein J.	0.501
ENSNMLP00000000284	ENSNMLP00000036683	ENSNMLP00000000284	ENSNMLP00000036683	Progesterone receptor.	Nuclear receptor coactivator 1.	0.951
ENSNMLP00000000284	ENSNMLP00000045074	ENSNMLP00000000284	ENSNMLP00000045074	Progesterone receptor.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.563
ENSNMLP00000000284	GATA2	ENSNMLP00000000284	ENSNMLP00000029035	Progesterone receptor.	GATA binding protein 2.	0.702
ENSNMLP00000000284	NR5A1	ENSNMLP00000000284	ENSNMLP00000017583	Progesterone receptor.	Nuclear receptor subfamily 5 group A member 1.	0.461
ENSNMLP00000000586	ENSNMLP00000003737	ENSNMLP00000000586	ENSNMLP00000003737	annotation not available	annotation not available	0.614
ENSNMLP00000000586	ENSNMLP00000004491	ENSNMLP00000000586	ENSNMLP00000004491	annotation not available	Transducin (beta)-like 1 X-linked receptor 1b.	0.652
ENSNMLP00000000586	ENSNMLP00000004564	ENSNMLP00000000586	ENSNMLP00000004564	annotation not available	Protein arginine methyltransferase 1.	0.722