(40 nodes) Negative regulation of gene expression, epigenetic network (Neogobius melanostomus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSNMLP00000015695	annotation not available (92 aa)
	ENSNMLP00000039298	Family with sequence similarity 172 member A. (422 aa)
	ENSNMLP00000038789	DNA (cytosine-5-)-methyltransferase 3 alpha a. (796 aa)
	ENSNMLP00000038044	SPT2 chromatin protein domain containing 1. (485 aa)
	ENSNMLP00000037512	annotation not available (607 aa)
	ENSNMLP00000035148	annotation not available (1473 aa)
	ENSNMLP00000034308	annotation not available (896 aa)
	ENSNMLP00000034307	annotation not available (707 aa)
	ENSNMLP00000032775	Methyl CpG binding protein 2. (551 aa)
	ENSNMLP00000031869	Protein phosphatase, Mg2+/Mn2+ dependent, 1Db. (553 aa)
	ENSNMLP00000031283	Histone acetyltransferase 1. (412 aa)
	ENSNMLP00000031117	Nurim. (266 aa)
	ENSNMLP00000025903	annotation not available (241 aa)
	EZH1	Enhancer of zeste 1 polycomb repressive complex 2 subunit. (799 aa)
	ENSNMLP00000024937	annotation not available (863 aa)
	ENSNMLP00000024936	annotation not available (943 aa)
	ENSNMLP00000024193	annotation not available (248 aa)
	ENSNMLP00000023393	annotation not available (118 aa)
	ENSNMLP00000020427	Lamin B1. (581 aa)
	ENSNMLP00000020179	Sirtuin 6. (347 aa)
	ENSNMLP00000018815	annotation not available (263 aa)
	ENSNMLP00000039818	annotation not available (247 aa)
	ENSNMLP00000015069	Retinoblastoma 1. (860 aa)
	PPM1D	Protein phosphatase, Mg2+/Mn2+ dependent 1D. (434 aa)
	ENSNMLP00000012957	annotation not available (114 aa)
	ENSNMLP00000012776	macroH2A.1 histone. (367 aa)
	ENSNMLP00000012459	methyl-CpG binding domain protein 3a. (285 aa)
	ENSNMLP00000011145	MORC family CW-type zinc finger 2. (1008 aa)
	ENSNMLP00000010128	DOT1-like histone H3K79 methyltransferase. (1574 aa)
	ENSNMLP00000009968	macroH2A.2 histone. (358 aa)
	ENSNMLP00000008045	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2. (1695 aa)
	ENSNMLP00000006581	SMYD family member 5. (422 aa)
	ENSNMLP00000005040	Sirtuin 1. (659 aa)
	ENSNMLP00000004506	annotation not available (695 aa)
	ENSNMLP00000002220	Lamin L3. (598 aa)
	ENSNMLP00000001942	Bmi1 polycomb ring finger oncogene 1a. (323 aa)
	ENSNMLP00000001657	Centromere protein V. (161 aa)
	ENSNMLP00000044411	BEN domain containing 3. (788 aa)
	ENSNMLP00000040369	Polymerase (DNA directed), epsilon 3 (p17 subunit). (144 aa)
	LMNA	Lamin A/C. (664 aa)

Your Current Organism:

Neogobius melanostomus

NCBI taxonomy Id: 47308
Other names: Apollonia melanostoma, Apollonia melanostomus, Gobius melanostomus, N. melanostomus, round goby

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSNMLP00000001942	ENSNMLP00000005040	ENSNMLP00000001942	ENSNMLP00000005040	Bmi1 polycomb ring finger oncogene 1a.	Sirtuin 1.	0.840
ENSNMLP00000001942	ENSNMLP00000009968	ENSNMLP00000001942	ENSNMLP00000009968	Bmi1 polycomb ring finger oncogene 1a.	macroH2A.2 histone.	0.474
ENSNMLP00000001942	ENSNMLP00000012776	ENSNMLP00000001942	ENSNMLP00000012776	Bmi1 polycomb ring finger oncogene 1a.	macroH2A.1 histone.	0.474
ENSNMLP00000001942	ENSNMLP00000015695	ENSNMLP00000001942	ENSNMLP00000015695	Bmi1 polycomb ring finger oncogene 1a.	annotation not available	0.882
ENSNMLP00000001942	ENSNMLP00000035148	ENSNMLP00000001942	ENSNMLP00000035148	Bmi1 polycomb ring finger oncogene 1a.	annotation not available	0.692
ENSNMLP00000001942	EZH1	ENSNMLP00000001942	ENSNMLP00000025067	Bmi1 polycomb ring finger oncogene 1a.	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	0.889
ENSNMLP00000002220	ENSNMLP00000004506	ENSNMLP00000002220	ENSNMLP00000004506	Lamin L3.	annotation not available	0.801
ENSNMLP00000002220	ENSNMLP00000015069	ENSNMLP00000002220	ENSNMLP00000015069	Lamin L3.	Retinoblastoma 1.	0.454
ENSNMLP00000002220	LMNA	ENSNMLP00000002220	ENSNMLP00000040078	Lamin L3.	Lamin A/C.	0.702
ENSNMLP00000004506	ENSNMLP00000002220	ENSNMLP00000004506	ENSNMLP00000002220	annotation not available	Lamin L3.	0.801
ENSNMLP00000004506	ENSNMLP00000015069	ENSNMLP00000004506	ENSNMLP00000015069	annotation not available	Retinoblastoma 1.	0.454
ENSNMLP00000004506	ENSNMLP00000020427	ENSNMLP00000004506	ENSNMLP00000020427	annotation not available	Lamin B1.	0.807
ENSNMLP00000004506	ENSNMLP00000037512	ENSNMLP00000004506	ENSNMLP00000037512	annotation not available	annotation not available	0.848
ENSNMLP00000004506	LMNA	ENSNMLP00000004506	ENSNMLP00000040078	annotation not available	Lamin A/C.	0.841
ENSNMLP00000005040	ENSNMLP00000001942	ENSNMLP00000005040	ENSNMLP00000001942	Sirtuin 1.	Bmi1 polycomb ring finger oncogene 1a.	0.840
ENSNMLP00000005040	ENSNMLP00000006581	ENSNMLP00000005040	ENSNMLP00000006581	Sirtuin 1.	SMYD family member 5.	0.427
ENSNMLP00000005040	ENSNMLP00000009968	ENSNMLP00000005040	ENSNMLP00000009968	Sirtuin 1.	macroH2A.2 histone.	0.418
ENSNMLP00000005040	ENSNMLP00000010128	ENSNMLP00000005040	ENSNMLP00000010128	Sirtuin 1.	DOT1-like histone H3K79 methyltransferase.	0.836
ENSNMLP00000005040	ENSNMLP00000012776	ENSNMLP00000005040	ENSNMLP00000012776	Sirtuin 1.	macroH2A.1 histone.	0.418
ENSNMLP00000005040	ENSNMLP00000015069	ENSNMLP00000005040	ENSNMLP00000015069	Sirtuin 1.	Retinoblastoma 1.	0.897