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| | KYC_01549 | Carbohydrate kinase; COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family. (496 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (144 aa) |
| | KYC_28742 | Response regulator 21; COG0515 Serine/threonine protein kinase. (458 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (328 aa) |
| | KYC_28472 | Receptor family ligand binding region family protein 31; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (390 aa) |
| | KYC_27918 | His Kinase A phosphoacceptor domain-containing protein 9; COG0642 Signal transduction histidine kinase. (450 aa) |
| | KYC_27738 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa) |
| | KYC_27733 | COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. (380 aa) |
| | KYC_27708 | Nucleotidyl transferase family protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (228 aa) |
| | KYC_27618 | Tetratricopeptide repeat family protein 12; COG0457 FOG: TPR repeat. (217 aa) |
| | KYC_27548 | Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (434 aa) |
| | KYC_27373 | Histidine kinase; COG0642 Signal transduction histidine kinase. (690 aa) |
| | KYC_27358 | Putative transmembrane sensor histidine kinase transcription regulator protein; COG3275 Putative regulator of cell autolysis. (366 aa) |
| | KYC_27333 | COG1573 Uracil-DNA glycosylase. (292 aa) |
| | KYC_27172 | COG3395 Uncharacterized protein conserved in bacteria. (405 aa) |
| | KYC_27037 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (476 aa) |
| | KYC_27017 | Tyrosine-protein kinase EpsB; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. (753 aa) |
| | acpS | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (142 aa) |
| | KYC_26612 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (190 aa) |
| | KYC_26467 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (523 aa) |
| | KYC_26447 | Response regulator receiver sensor signal transduction histidine kinase; COG0784 FOG: CheY-like receiver. (379 aa) |
| | KYC_26432 | COG0642 Signal transduction histidine kinase. (1137 aa) |
| | KYC_26342 | Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. (321 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (347 aa) |
| | KYC_26107 | Trm112p-like family protein; Belongs to the UPF0434 family. (60 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (254 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | KYC_25628 | 2-dehydro-3-deoxygalactonokinase; COG3734 2-keto-3-deoxy-galactonokinase. (335 aa) |
| | KYC_25433 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (395 aa) |
| | KYC_25408 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (788 aa) |
| | KYC_25403 | PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (275 aa) |
| | KYC_25343 | Phosphatidate cytidylyltransferase; COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. (285 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa) |
| | glnD | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (868 aa) |
| | KYC_25082 | COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (405 aa) |
| | KYC_25012 | COG0642 Signal transduction histidine kinase. (463 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (204 aa) |
| | KYC_24892 | Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (173 aa) |
| | KYC_24352 | His Kinase A phosphoacceptor domain-containing protein 10; COG0642 Signal transduction histidine kinase. (403 aa) |
| | KYC_24307 | SlyX family protein. (71 aa) |
| | KYC_24112 | EAL domain-containing protein 5; COG1455 Phosphotransferase system cellobiose-specific component IIC. (701 aa) |
| | KYC_23987 | Ribose-phosphate diphosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (277 aa) |
| | KYC_23613 | Receptor family ligand binding region family protein 27; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (400 aa) |
| | KYC_23593 | Receptor family ligand binding region family protein 27; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (398 aa) |
| | KYC_23423 | COG3524 Capsule polysaccharide export protein. (390 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (378 aa) |
| | KYC_23323 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (396 aa) |
| | KYC_23238 | HAMP domain-containing protein 17; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation. (770 aa) |
| | KYC_23033 | Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (151 aa) |
| | hprK | HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (308 aa) |
| | KYC_22963 | COG0548 Acetylglutamate kinase. (46 aa) |
| | KYC_22936 | Histidine kinase, Classic; COG0642 Signal transduction histidine kinase. (439 aa) |
| | KYC_22696 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (412 aa) |
| | KYC_22566 | Glycosyl transferase family 4 protein 1; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase. (368 aa) |
| | KYC_22496 | HAMP domain-containing protein 16; COG0642 Signal transduction histidine kinase. (447 aa) |
| | ipk | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (303 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa) |
| | KYC_22096 | COG0642 Signal transduction histidine kinase. (429 aa) |
| | glmU | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (457 aa) |
| | holA | COG1466 DNA polymerase III, delta subunit. (351 aa) |
| | KYC_21746 | Receptor family ligand binding region family protein 21; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (409 aa) |
| | KYC_21651 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (526 aa) |
| | KYC_21411 | HAMP domain-containing protein 9; COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific. (645 aa) |
| | dnaE2 | Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1079 aa) |
| | KYC_21124 | COG0527 Aspartokinases; Belongs to the aspartokinase family. (421 aa) |
| | KYC_20679 | COG2200 FOG: EAL domain. (304 aa) |
| | KYC_20584 | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (479 aa) |
| | KYC_20574 | Sensory box protein 6; COG2203 FOG: GAF domain. (990 aa) |
| | KYC_20449 | RES domain-containing protein. (170 aa) |
| | KYC_20239 | COG3852 Signal transduction histidine kinase, nitrogen specific. (354 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (227 aa) |
| | KYC_20194 | Hypothetical protein; COG1561 Uncharacterized stress-induced protein. (310 aa) |
| | KYC_20134 | tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (366 aa) |
| | KYC_20029 | Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (396 aa) |
| | KYC_19919 | Glucose-1-phosphate cytidylyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (256 aa) |
| | fliA | RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (251 aa) |
| | KYC_19874 | COG0643 Chemotaxis protein histidine kinase and related kinases. (168 aa) |
| | KYC_19689 | Polyphosphate kinase. (401 aa) |
| | KYC_19539 | COG4585 Signal transduction histidine kinase. (672 aa) |
| | KYC_19359 | Hypothetical protein. (700 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (508 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa) |
| | KYC_19104 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (265 aa) |
| | KYC_19004 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (260 aa) |
| | KYC_18855 | C4-dicarboxylate transport sensor protein DctB; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. (649 aa) |
| | nadD | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (195 aa) |
| | glnE | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] (925 aa) |
| | ndk | Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa) |
| | KYC_18450 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (622 aa) |
| | KYC_18435 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (398 aa) |
| | KYC_18385 | Response regulator 12; COG0784 FOG: CheY-like receiver. (130 aa) |
| | thrB | COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. (322 aa) |
| | selO | Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (495 aa) |
| | KYC_18080 | COG0642 Signal transduction histidine kinase. (478 aa) |
| | KYC_18070 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (460 aa) |
| | selD | Selenophosphate synthetase; Synthesizes selenophosphate from selenide and ATP. (353 aa) |
| | KYC_17192 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (491 aa) |
| | dnaE | COG0587 DNA polymerase III, alpha subunit. (1165 aa) |
| | KYC_17077 | Hypothetical protein. (215 aa) |
| | kdkA | 3-deoxy-D-manno-octulosonic-acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (244 aa) |
| | KYC_16957 | His Kinase A phosphoacceptor domain-containing protein 5; COG0642 Signal transduction histidine kinase. (341 aa) |
| | KYC_16822 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (524 aa) |
| | KYC_16547 | COG0642 Signal transduction histidine kinase. (503 aa) |
| | KYC_16422 | Hypothetical protein; COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily. (243 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (905 aa) |
| | KYC_16207 | HAMP domain-containing protein 6; COG0642 Signal transduction histidine kinase. (442 aa) |
| | KYC_16057 | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (432 aa) |
| | KYC_16052 | Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. (302 aa) |
| | KYC_15967 | D-beta-D-heptose 7-phosphate kinase; COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase. (313 aa) |
| | cmk | COG0283 Cytidylate kinase. (229 aa) |
| | KYC_15612 | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (132 aa) |
| | thiL | Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (321 aa) |
| | KYC_15502 | Diguanylate cyclase YeaP; COG2199 FOG: GGDEF domain. (352 aa) |
| | KYC_15287 | Polyphosphate kinase. (278 aa) |
| | KYC_15262 | COG1793 ATP-dependent DNA ligase. (842 aa) |
| | aoxS | COG0642 Signal transduction histidine kinase. (501 aa) |
| | KYC_14492 | Periplasmic sensor hybrid histidine kinase; COG0642 Signal transduction histidine kinase. (920 aa) |
| | KYC_14487 | Response regulator receiver modulated; COG0784 FOG: CheY-like receiver. (406 aa) |
| | KYC_14462 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (516 aa) |
| | KYC_14457 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (587 aa) |
| | KYC_14165 | COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (143 aa) |
| | dnaQ | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (241 aa) |
| | KYC_13865 | DNA polymerase III, delta' subunit; COG0470 ATPase involved in DNA replication. (349 aa) |
| | anmK | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (377 aa) |
| | KYC_13713 | Phosphatidylethanolamine-binding family protein; COG1881 Phospholipid-binding protein. (217 aa) |
| | KYC_13683 | PrkA family serine protein kinase; COG2766 Putative Ser protein kinase. (641 aa) |
| | pgk | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | ackA | Acetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) |
| | mogA | Molybdenum cofactor biosynthesis protein MogA; COG0521 Molybdopterin biosynthesis enzymes. (210 aa) |
| | phnN | Phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (192 aa) |
| | KYC_13127 | SUA5 domain-containing protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (349 aa) |
| | KYC_12353 | COG0642 Signal transduction histidine kinase. (380 aa) |
| | pdxK | Pyridoxal-pyridoxamine kinase/hydroxymethylpyrimidine kinase; COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family. (287 aa) |
| | KYC_11973 | COG0095 Lipoate-protein ligase A. (258 aa) |
| | KYC_11808 | COG4564 Signal transduction histidine kinase. (473 aa) |
| | KYC_11748 | Hypothetical protein; COG2202 FOG: PAS/PAC domain. (314 aa) |
| | KYC_11713 | HAMP domain-containing protein 8; COG0642 Signal transduction histidine kinase. (492 aa) |
| | KYC_11693 | hydroxymethylglutaryl-CoA reductase, degradative; COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (428 aa) |
| | KYC_11268 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (758 aa) |
| | KYC_11043 | COG2927 DNA polymerase III, chi subunit. (153 aa) |
| | KYC_10431 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (389 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (365 aa) |
| | KYC_09936 | COG3570 Streptomycin 6-kinase. (275 aa) |
| | KYC_09495 | HAMP domain-containing protein 5; COG0642 Signal transduction histidine kinase. (474 aa) |
| | KYC_09335 | Hypothetical protein. (228 aa) |
| | pnp | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (720 aa) |
| | KYC_09180 | CDP-diacylglycerol--serine O-phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (257 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (227 aa) |
| | KYC_09000 | Diacylglycerol kinase catalytic domain-containing protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase. (324 aa) |
| | KYC_08840 | Hypothetical protein; COG2199 FOG: GGDEF domain. (390 aa) |
| | KYC_08330 | Two-component system sensor protein; COG0642 Signal transduction histidine kinase. (416 aa) |
| | KYC_08145 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (268 aa) |
| | KYC_07950 | Glycosyl transferase family protein; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase. (367 aa) |
| | KYC_07770 | COG3530 Uncharacterized protein conserved in bacteria. (74 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (201 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (67 aa) |
| | KYC_06686 | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (450 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (389 aa) |
| | KYC_06325 | Diguanylate cyclase; COG2199 FOG: GGDEF domain. (555 aa) |
| | KYC_06021 | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (552 aa) |
| | KYC_06011 | COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. (133 aa) |
| | ubiB | Putative ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (517 aa) |
| | KYC_05821 | D-beta-D-heptose 1-phosphate adenosyltransferase; COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase. (162 aa) |
| | KYC_05806 | COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (280 aa) |
| | KYC_05736 | Polyphosphate kinase. (488 aa) |
| | KYC_05646 | Receptor family ligand binding region family protein 29; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (387 aa) |
| | KYC_05536 | COG0548 Acetylglutamate kinase; Belongs to the acetylglutamate kinase family. ArgB subfamily. (235 aa) |
| | KYC_05531 | COG0643 Chemotaxis protein histidine kinase and related kinases. (414 aa) |
| | KYC_05396 | COG0524 Sugar kinases, ribokinase family. (313 aa) |
| | KYC_05164 | Heavy metal sensor kinase family protein 1; Member of a two-component regulatory system. (458 aa) |
| | KYC_05154 | Phosphate regulon sensor kinase PhoR; COG0642 Signal transduction histidine kinase. (435 aa) |
| | KYC_04767 | Bifunctional serine/threonine kinase and phosphatase; COG0631 Serine/threonine protein phosphatase. (583 aa) |
| | KYC_04697 | COG3395 Uncharacterized protein conserved in bacteria. (447 aa) |
| | KYC_04512 | HAMP domain-containing protein 14; COG0642 Signal transduction histidine kinase. (466 aa) |
| | KYC_04287 | RisS protein; COG0642 Signal transduction histidine kinase. (446 aa) |
| | KYC_04217 | His Kinase A phosphoacceptor domain-containing protein 7; COG0642 Signal transduction histidine kinase. (479 aa) |
| | KYC_03617 | Pyruvate phosphate dikinase, PEP/pyruvate binding domain-containing protein; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (669 aa) |
| | KYC_03409 | Sensor protein KdpD; COG2205 Osmosensitive K+ channel histidine kinase. (928 aa) |
| | ppnK | NAD(+)/NADH kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (299 aa) |
| | KYC_03119 | UTP-glucose-1-phosphate uridylyltransferase; COG1210 UDP-glucose pyrophosphorylase. (283 aa) |
| | KYC_03034 | HAMP domain-containing protein 3; COG0642 Signal transduction histidine kinase. (528 aa) |
| | KYC_02844 | COG0524 Sugar kinases, ribokinase family. (310 aa) |
| | pcnB | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (456 aa) |
| | KYC_02634 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (162 aa) |
| | KYC_02629 | COG0524 Sugar kinases, ribokinase family; Belongs to the carbohydrate kinase PfkB family. (298 aa) |
| | KYC_02214 | Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (433 aa) |
| | KYC_02109 | CheA signal transduction histidine kinase 2; COG0643 Chemotaxis protein histidine kinase and related kinases. (770 aa) |
| | KYC_02099 | COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain. (349 aa) |
| | KYC_01864 | Sensory box protein 4; COG2202 FOG: PAS/PAC domain. (543 aa) |
| | KYC_01739 | C4-dicarboxylate transport sensor protein DctS; COG2202 FOG: PAS/PAC domain. (584 aa) |
| | KYC_01629 | KWG Leptospira family protein 2. (963 aa) |
| | KYC_01624 | KWG Leptospira family protein 1. (1023 aa) |
| | dnaX | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (712 aa) |
| | KYC_01435 | Hypothetical protein. (220 aa) |
| | KYC_01430 | Response regulator receiver protein; COG0784 FOG: CheY-like receiver. (121 aa) |
| | KYC_01425 | COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase). (688 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (679 aa) |
| | KYC_00930 | COG0642 Signal transduction histidine kinase. (510 aa) |
| | KYC_00796 | His Kinase A phosphoacceptor domain-containing protein 13; COG4252 Predicted transmembrane sensor domain. (768 aa) |
| | KYC_00791 | COG0515 Serine/threonine protein kinase. (421 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1414 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1370 aa) |
| | aceK | Bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (624 aa) |
| | KYC_00595 | Hypothetical protein. (405 aa) |
| | KYC_00245 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (369 aa) |
| | KYC_00135 | His Kinase A phosphoacceptor domain-containing protein 14; COG0642 Signal transduction histidine kinase. (470 aa) |
