(42 nodes) Mixed, incl. Polyketide synthase, phosphopantetheine-binding domain, and Thioesterase type II, NRPS/PKS/S-FAS network (Streptomyces cyaneogriseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AJP05428.1	Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
	AJP00314.1	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1947 aa)
	AJP00321.1	Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
	nemG	oleoyl-ACP hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
	AJP05473.1	malonyl-CoA O-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1096 aa)
	AJP00629.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2763 aa)
	AJP00630.1	Thioester reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3069 aa)
	AJP05474.1	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2853 aa)
	AJP00632.1	Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
	AJP00633.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
	AJP00634.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
	AJP00635.1	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1799 aa)
	AJP00639.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2096 aa)
	AJP00658.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1307 aa)
	AJP00659.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
	AJP00665.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
	AJP00666.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (168 aa)
	AJP00667.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (135 aa)
	AJP05493.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	AJP00810.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
	AJP00811.1	Antibiotic synthesis protein MbtH; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
	AJP00812.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
	AJP01002.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
	AJP03823.1	oleoyl-ACP hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
	AJP03824.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (59 aa)
	AJP03825.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (4798 aa)
	AJP03826.1	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3943 aa)
	AJP03827.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (4654 aa)
	AJP03909.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (655 aa)
	AJP03910.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
	AJP04523.1	Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
	AJP04705.1	NRPS-type-I PKS fusion protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2470 aa)
	AJP04992.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (4963 aa)
	AJP05951.1	Thioester reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2317 aa)
	AJP04993.1	Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsD; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
	AJP05037.1	Protein mbtH; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)
	AJP05974.1	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (6673 aa)
	AJP05136.1	Antibiotic synthesis protein MbtH; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
	AJP05138.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. (1440 aa)
	AJP05167.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
	AJP05984.1	Adenylate-forming protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (597 aa)
	AJP06017.1	Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2396 aa)

Your Current Organism:

Streptomyces cyaneogriseus

NCBI taxonomy Id: 477245
Other names: S. cyaneogriseus subsp. noncyanogenus, Streptomyces cyaneogriseus subsp. noncyanogenus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJP00314.1	AJP00321.1	TU94_00870	TU94_00915	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.838
AJP00314.1	AJP00629.1	TU94_00870	TU94_02960	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.703
AJP00314.1	AJP00630.1	TU94_00870	TU94_02965	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Thioester reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AJP00314.1	AJP00632.1	TU94_00870	TU94_02995	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type I polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
AJP00314.1	AJP00633.1	TU94_00870	TU94_03010	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
AJP00314.1	AJP00634.1	TU94_00870	TU94_03015	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
AJP00314.1	AJP00635.1	TU94_00870	TU94_03030	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
AJP00314.1	AJP00639.1	TU94_00870	TU94_03065	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
AJP00314.1	AJP00658.1	TU94_00870	TU94_03195	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AJP00314.1	AJP00659.1	TU94_00870	TU94_03210	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.426
AJP00314.1	AJP00665.1	TU94_00870	TU94_03280	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.967
AJP00314.1	AJP00666.1	TU94_00870	TU94_03285	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.984
AJP00314.1	AJP00667.1	TU94_00870	TU94_03295	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.989
AJP00314.1	AJP00810.1	TU94_00870	TU94_04245	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AJP00314.1	AJP00811.1	TU94_00870	TU94_04255	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Antibiotic synthesis protein MbtH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.499
AJP00314.1	AJP00812.1	TU94_00870	TU94_04265	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.832
AJP00314.1	AJP01002.1	TU94_00870	TU94_05490	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.964
AJP00314.1	AJP03823.1	TU94_00870	TU94_22425	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	oleoyl-ACP hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.837
AJP00314.1	AJP03824.1	TU94_00870	TU94_22445	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.988
AJP00314.1	AJP03825.1	TU94_00870	TU94_22460	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990