STRINGSTRING
AJP05328.1 AJP05328.1 AJP00301.1 AJP00301.1 AJP00530.1 AJP00530.1 AJP00649.1 AJP00649.1 hutU hutU AJP05522.1 AJP05522.1 AJP05531.1 AJP05531.1 AJP01292.1 AJP01292.1 ectC ectC AJP01445.1 AJP01445.1 AJP01446.1 AJP01446.1 AJP01449.1 AJP01449.1 dapA dapA aroQ aroQ psuG psuG trpA trpA trpB trpB hisB hisB AJP01626.1 AJP01626.1 AJP01787.1 AJP01787.1 AJP01952.1 AJP01952.1 AJP02106.1 AJP02106.1 AJP02243.1 AJP02243.1 hutU-2 hutU-2 eno eno ilvD ilvD AJP02635.1 AJP02635.1 AJP02899.1 AJP02899.1 AJP03195.1 AJP03195.1 AJP03202.1 AJP03202.1 mqnA mqnA AJP03307.1 AJP03307.1 nnrD nnrD aspA aspA AJP03596.1 AJP03596.1 AJP03652.1 AJP03652.1 leuC leuC leuD leuD dapA-2 dapA-2 AJP04250.1 AJP04250.1 AJP04284.1 AJP04284.1 acnA acnA AJP04385.1 AJP04385.1 AJP04637.1 AJP04637.1 AJP04695.1 AJP04695.1 AJP04812.1 AJP04812.1 AJP04885.1 AJP04885.1 AJP05151.1 AJP05151.1 gudD gudD AJP05158.1 AJP05158.1 AJP05285.1 AJP05285.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJP05328.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
AJP00301.1VlmK-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
AJP00530.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
AJP00649.1NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (561 aa)
AJP05522.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
AJP05531.1Anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
AJP01292.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (132 aa)
AJP01445.1Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (584 aa)
AJP01446.1Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (302 aa)
AJP01449.15-dehydro-4-deoxyglucarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (313 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (157 aa)
psuGPseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (302 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (271 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (428 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
AJP01626.1Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
AJP01787.13-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
AJP01952.1Glucarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (430 aa)
AJP02106.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
AJP02243.1Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
hutU-2Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (572 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (617 aa)
AJP02635.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (779 aa)
AJP02899.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
AJP03195.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
AJP03202.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (331 aa)
mqnAMenaquinone biosynthesis protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (282 aa)
AJP03307.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (150 aa)
nnrDCarbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (482 aa)
aspAAspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (471 aa)
AJP03596.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (558 aa)
AJP03652.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (475 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
AJP04250.1Fuconate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (448 aa)
AJP04284.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
acnAAconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (944 aa)
AJP04385.1Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (193 aa)
AJP04637.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
AJP04695.1Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AJP04812.14-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
AJP04885.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AJP05151.15-dehydro-4-deoxyglucarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (308 aa)
gudDGlucarate dehydratase; Catalyzes the formation of 5-keto-4-deoxy-D-glucarate from glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (444 aa)
AJP05158.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
AJP05285.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (326 aa)
Your Current Organism:
Streptomyces cyaneogriseus
NCBI taxonomy Id: 477245
Other names: S. cyaneogriseus subsp. noncyanogenus, Streptomyces cyaneogriseus subsp. noncyanogenus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.