Your Input: | |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (132 aa) |
| | dnaN | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (387 aa) |
| | CCH85588.1 | Homologs of previously reported genes of unknown function. (400 aa) |
| | accB | Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (582 aa) |
| | sucD | Succinyl-CoA synthetase, alpha subunit; Function of strongly homologous gene; enzyme. (490 aa) |
| | CCH85640.1 | Homologs of previously reported genes of unknown function. (471 aa) |
| | ureB | Urease beta subunit (modular protein); Function of strongly homologous gene; enzyme. (140 aa) |
| | glpD | Glycerol-3-phosphate dehydrogenase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (498 aa) |
| | CCH85763.1 | Homologs of previously reported genes of unknown function. (182 aa) |
| | fdhA2 | Formate dehydrogenase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (874 aa) |
| | cysC | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (342 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (756 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (499 aa) |
| | trwC | Conjugative relaxase TrwC; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1191 aa) |
| | uvrA | Excision nuclease ABC subunit; Function of strongly homologous gene; enzyme. (797 aa) |
| | accD-2 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Function of strongly homologous gene; enzyme. (508 aa) |
| | eno | Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | xseB | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (71 aa) |
| | xseA | Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (407 aa) |
| | CCH86646.1 | Citrate lyase beta subunit; Function of strongly homologous gene; enzyme; Belongs to the HpcH/HpaI aldolase family. (317 aa) |
| | fdnI | Formate dehydrogenase gamma subunit; Function of strongly homologous gene; enzyme. (215 aa) |
| | CCH86897.1 | Methylcrotonoyl-CoA carboxylase; Function of strongly homologous gene; enzyme. (537 aa) |
| | nuoM | NADH-quinone oxidoreductase subunit M; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (538 aa) |
| | CCH87103.1 | Putative Ferrous iron permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter. (282 aa) |
| | dnaG | DNA primase; Function of strongly homologous gene; enzyme. (1832 aa) |
| | clpX | ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (424 aa) |
| | CCH87179.1 | DNA polymerase III, delta subunit; Function of strongly homologous gene; enzyme. (278 aa) |
| | dnaG-2 | DNA primase (modular protein); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (792 aa) |
| | pccB | Propionyl-CoA carboxylase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (471 aa) |
| | aceE | Fragment of conserved protein of unknown function (part 1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (937 aa) |
| | CCH87429.1 | Excinuclease ABC C subunit domain protein. (305 aa) |
| | ku | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (331 aa) |
| | CCH87541.1 | Putative citrate lyase beta chain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the HpcH/HpaI aldolase family. (279 aa) |
| | poxB | Pyruvate dehydrogenase/oxidase: FAD-and thiamine PPi-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family. (578 aa) |
| | CCH87627.1 | Glycoside hydrolase; Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 2 family. (796 aa) |
| | uidA | Beta-glucuronidase; Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 2 family. (597 aa) |
| | paaC | Phenylacetic acid degradation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (297 aa) |
| | paaB | Phenylacetate-CoA oxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (121 aa) |
| | paaA | Phenylacetic acid degradation protein paaA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (321 aa) |
| | CCH87734.1 | Homologs of previously reported genes of unknown function. (154 aa) |
| | CCH87838.1 | Glutamine amidotransferases class-II; Function of strongly homologous gene; enzyme. (277 aa) |
| | CCH87887.1 | acetyl-CoA carboxylase, biotin carboxylase subunit; Function of strongly homologous gene; enzyme. (1840 aa) |
| | CCH87919.1 | RNA polymerase, sigma 54 (sigma N) factor; Function of strongly homologous gene; factor. (420 aa) |
| | CCH88009.1 | Putative ATP-dependent exoDNAse (Exonuclease V), alpha subunit/helicase superfamily I member; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (648 aa) |
| | CCH88014.1 | Phosphatidylinositol 3-and 4-kinase; Function of strongly homologous gene; enzyme. (284 aa) |
| | trmI | tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (319 aa) |
| | arc | Putative AAA+ family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (592 aa) |
| | prcB | Proteasome endopeptidase complex, beta component; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. (280 aa) |
| | prcA | 20S proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. (303 aa) |
| | gcvP | Glycine cleavage system P-protein (glycine dehydrogenase); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (1000 aa) |
| | gcvH | Glycine cleavage system H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (134 aa) |
| | CCH88187.1 | Glycoside hydrolase; Function of strongly homologous gene; enzyme. (548 aa) |
| | CCH88205.1 | Glutamine amidotransferase; Function of strongly homologous gene; enzyme. (273 aa) |
| | CCH88400.1 | Glycoside hydrolase family 2 sugar binding; Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 2 family. (805 aa) |
| | uidA-2 | Beta-glucuronidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glycosyl hydrolase 2 family. (584 aa) |
| | uidA-3 | Beta-glucuronidase; Function of strongly homologous gene; enzyme. (117 aa) |
| | CCH88502.1 | Pyruvate carboxylase (fragment); Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1117 aa) |
| | dnaG-3 | DNA primase; Function of strongly homologous gene; enzyme. (1844 aa) |
| | nasC | Assimilatory nitrate reductase catalytic subunit; Function of strongly homologous gene; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (851 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (169 aa) |
| | coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (406 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (87 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Function of strongly homologous gene; enzyme; Belongs to the CarA family. (386 aa) |
| | efeU | Ferrous iron permease efeU; Function of strongly homologous gene; transporter. (297 aa) |
| | ruvB | Holliday junction DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (375 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (212 aa) |
| | pdxT | Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (221 aa) |
| | polC | DNA-directed DNA polymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (649 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Function of strongly homologous gene; enzyme. (623 aa) |
| | uvrC | Excinuclease, UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (689 aa) |
| | uvrA-2 | UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A)(Excinuclease ATPase subunit); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (978 aa) |
| | uvrB | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (705 aa) |
| | CCH89109.1 | Putative NADH dehydrogenase (quinone); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (455 aa) |
| | dnaG-4 | DNA primase; Function of strongly homologous gene; enzyme. (1824 aa) |
| | eutC | Ethanolamine ammonia-lyase light chain (Ethanolamine ammonia-lyase small subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the EutC family. (248 aa) |
| | eutB | Ethanolamine ammonia-lyase heavy chain (Ethanolamine ammonia-lyase large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (470 aa) |
| | CCH89461.1 | Homologs of previously reported genes of unknown function. (278 aa) |
| | CCH89485.1 | Homologs of previously reported genes of unknown function. (906 aa) |
| | CCH89514.1 | Putative nuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (546 aa) |
| | CCH89530.1 | Type III restriction enzyme, restriction (R) subunit; Function of strongly homologous gene; enzyme. (1139 aa) |
| | CCH89531.1 | Type-1 restriction enzyme StySPI; Function of strongly homologous gene; enzyme. (394 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Function of strongly homologous gene; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (691 aa) |
| | leuD | 3-isopropylmalate dehydratase (small subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | sucA | 2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme. (1275 aa) |
| | CCH90035.1 | Homologs of previously reported genes of unknown function. (220 aa) |
| | CCH90146.1 | Putative propionyl-CoA carboxylase beta chain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (542 aa) |
| | CCH90147.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (69 aa) |
| | sucD-2 | succinyl-CoA synthetase, alpha subunit, NAD(P)-binding; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa) |
| | pcrA | ATP-dependent DNA helicase pcrA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (763 aa) |
| | rpoA | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (355 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1299 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1164 aa) |
| | nuoM-2 | NADH-quinone oxidoreductase subunit M; Function of strongly homologous gene; enzyme. (549 aa) |
| | nuoG | NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (841 aa) |
| | nuoF | NADH-quinone oxidoreductase chain F (NADH dehydrogenase I, chain F) (NDH-1, chain F); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (443 aa) |
| | CCH90346.1 | NADH:ubiquinone oxidoreductase, chain E; Function of strongly homologous gene; carrier. (334 aa) |
| | cysD | Sulfate adenylate transferase, subunit 2 (NodP-like); Function of strongly homologous gene; enzyme. (302 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (435 aa) |
| | trwC-2 | Conjugative relaxase TrwC; Function of strongly homologous gene; enzyme. (1208 aa) |
| | pyc-2 | Pyruvate carboxylase (fragment); Function of strongly homologous gene; enzyme. (911 aa) |
| | kynA | Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (307 aa) |
| | glpD-2 | Glycerol-3-phosphate dehydrogenase 2; Function of strongly homologous gene; enzyme; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (576 aa) |
