STRINGSTRING
accC accC accB accB CCH85681.1 CCH85681.1 fadI fadI lldD lldD leuA leuA acsA acsA CCH86254.1 CCH86254.1 CCH86256.1 CCH86256.1 ppc ppc fadA-2 fadA-2 fumC fumC CCH86900.1 CCH86900.1 CCH87101.1 CCH87101.1 pccB pccB aceE aceE poxB poxB ppsA ppsA pps pps CCH88131.1 CCH88131.1 aceB aceB pckG pckG CCH88351.1 CCH88351.1 CCH88502.1 CCH88502.1 CCH88762.1 CCH88762.1 pyk pyk mqo mqo bfmBC bfmBC lldD-2 lldD-2 CCH89291.1 CCH89291.1 phbA phbA CCH89436.1 CCH89436.1 CCH89820.1 CCH89820.1 leuA-2 leuA-2 CCH89903.1 CCH89903.1 CCH89967.1 CCH89967.1 bccA bccA ald-2 ald-2 mdh mdh korA korA korB korB aceB-2 aceB-2 pdhC pdhC pdhB pdhB pdhA pdhA pckG-2 pckG-2 pyc-2 pyc-2 lldD-3 lldD-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
accCCarbamoyl-phosphate synthase L chain ATP-binding protein; Function of strongly homologous gene; enzyme. (579 aa)
accBAcetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa)
CCH85681.1NAD-dependent malic enzyme; Function of strongly homologous gene; enzyme. (490 aa)
fadI3-ketoacyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (435 aa)
lldDLactate 2-monooxygenase; Function of strongly homologous gene; enzyme. (432 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (577 aa)
acsAAcetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
CCH86254.1Putative Rhodanese-related sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (461 aa)
CCH86256.1Thiosulfate:cyanide sulfurtransferase (rhodanese); Function of strongly homologous gene; enzyme. (354 aa)
ppcPhosphoenolpyruvate carboxylase, Carbon dioxide fixing enzyme; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (923 aa)
fadA-23-ketoacyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
CCH86900.1Acetyl/propionyl-CoA carboxylase, alpha subunit; Function of strongly homologous gene; enzyme. (666 aa)
CCH87101.1Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (455 aa)
pccBPropionyl-CoA carboxylase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (471 aa)
aceEFragment of conserved protein of unknown function (part 1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (937 aa)
poxBPyruvate dehydrogenase/oxidase: FAD-and thiamine PPi-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family. (578 aa)
ppsAPhosphoenolpyruvate synthase/pyruvate phosphate dikinase; Function of strongly homologous gene; enzyme. (289 aa)
ppsPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)
CCH88131.1Butyrate--CoA ligase; Function of strongly homologous gene; enzyme. (567 aa)
aceBMalate synthase; Function of strongly homologous gene; enzyme. (548 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (620 aa)
CCH88351.1Aldehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (492 aa)
CCH88502.1Pyruvate carboxylase (fragment); Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1117 aa)
CCH88762.1Putative enzymemetal binding hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (227 aa)
pykPyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family. (471 aa)
mqoMalate:quinone oxidoreductase; Function of strongly homologous gene; enzyme. (484 aa)
bfmBCDihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (459 aa)
lldD-2L-lactate dehydrogenase [cytochrome] 2; Function of strongly homologous gene; enzyme. (404 aa)
CCH89291.1Glyoxalase/bleomycin resistance protein/dioxygenase; Function of strongly homologous gene; cell process. (281 aa)
phbAacetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
CCH89436.1Homologs of previously reported genes of unknown function. (423 aa)
CCH89820.1Acylphosphatase; Function of strongly homologous gene; enzyme. (90 aa)
leuA-22-isopropylmalate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the alpha-IPM synthase/homocitrate synthase family. (545 aa)
CCH89903.1acetyl-CoA acetyltransferase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)
CCH89967.1Pyruvate carboxylase; Function of strongly homologous gene; enzyme. (74 aa)
bccAAcetyl-/propionyl-coenzyme A carboxylase alpha chain [Biotin carboxylase; Function of strongly homologous gene; enzyme. (587 aa)
ald-2Aldehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (480 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (317 aa)
korA2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme. (667 aa)
korB2-oxoacid:ferredoxin oxidoreductase, beta subunit; Function of strongly homologous gene; enzyme. (370 aa)
aceB-2Malate synthase; Function of strongly homologous gene; enzyme; Belongs to the malate synthase family. (533 aa)
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of strongly homologous gene; enzyme. (499 aa)
pdhBPyruvate dehydrogenase E1 component subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (325 aa)
pdhAPyruvate dehydrogenase E1 component, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (378 aa)
pckG-2Phosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (604 aa)
pyc-2Pyruvate carboxylase (fragment); Function of strongly homologous gene; enzyme. (911 aa)
lldD-3L-lactate dehydrogenase; Function of strongly homologous gene; enzyme. (433 aa)
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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