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| | gndA | 6-phosphogluconate dehydrogenase (Decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (315 aa) |
| | CCH85503.1 | Putative Aldose 1-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (306 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (342 aa) |
| | fadB | enoyl-CoA hydratase; Function of strongly homologous gene; enzyme. (259 aa) |
| | mmgB | 3-hydroxybutyryl-CoA dehydrogenase; Function of strongly homologous gene; enzyme. (287 aa) |
| | fadA | 3-ketoacyl-CoA thiolase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa) |
| | glxK | Glycerate kinase; Function of strongly homologous gene; enzyme; Belongs to the glycerate kinase type-1 family. (368 aa) |
| | uox | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. (301 aa) |
| | yedX | 5-hydroxyisourate hydrolase; Function of strongly homologous gene; enzyme; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (105 aa) |
| | CCH85587.1 | Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Function of strongly homologous gene; enzyme. (175 aa) |
| | nemA | N-ethylmaleimide reductase; Function of strongly homologous gene; enzyme. (360 aa) |
| | accC | Carbamoyl-phosphate synthase L chain ATP-binding protein; Function of strongly homologous gene; enzyme. (579 aa) |
| | accB | Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa) |
| | arcC | Carbamate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the carbamate kinase family. (318 aa) |
| | ureA | Urease subunit gamma; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the urease gamma subunit family. (100 aa) |
| | ureB | Urease beta subunit (modular protein); Function of strongly homologous gene; enzyme. (140 aa) |
| | ureC | Urease alpha subunit (Urea amidohydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (573 aa) |
| | allB | Allantoinase; Function of strongly homologous gene; enzyme. (441 aa) |
| | allC | Allantoicase; Function of strongly homologous gene; enzyme; Belongs to the allantoicase family. (373 aa) |
| | CCH85685.1 | Putative Haloacid dehalogenase, type II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (227 aa) |
| | CCH85714.1 | Class II aldolase/adducin family protein; Function of strongly homologous gene; enzyme. (224 aa) |
| | dhaA | Haloalkane dehalogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (301 aa) |
| | CAD | Mannitol dehydrogenase; Function of strongly homologous gene; enzyme. (347 aa) |
| | amdA | Amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the amidase family. (511 aa) |
| | fadI | 3-ketoacyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (435 aa) |
| | fdhA1 | Formate dehydrogenase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (186 aa) |
| | fdhA2 | Formate dehydrogenase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (874 aa) |
| | fdhB | Formate dehydrogenase, beta subunit; Function of strongly homologous gene; enzyme. (357 aa) |
| | CCH85943.1 | Inositol monophosphatase; Function of strongly homologous gene; enzyme. (246 aa) |
| | cysC | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (342 aa) |
| | ask | Aspartokinase; Function of strongly homologous gene; enzyme; Belongs to the aspartokinase family. (421 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa) |
| | acsA | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa) |
| | cysG | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. (409 aa) |
| | CCH86128.1 | Phosphoglycerate mutase; Function of strongly homologous gene; enzyme; Belongs to the phosphoglycerate mutase family. (188 aa) |
| | thrC | L-threonine synthase; Function of strongly homologous gene; enzyme. (433 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (460 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (371 aa) |
| | citA | Citrate synthase 2; Function of strongly homologous gene; enzyme; Belongs to the citrate synthase family. (376 aa) |
| | pdxH | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (215 aa) |
| | ppc | Phosphoenolpyruvate carboxylase, Carbon dioxide fixing enzyme; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (923 aa) |
| | CCH86353.1 | Aldose 1-epimerase; Function of strongly homologous gene; enzyme. (298 aa) |
| | CCH86387.1 | Enoyl-CoA hydratase/isomerase; Function of strongly homologous gene; enzyme. (260 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | eno | Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | fadA-2 | 3-ketoacyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa) |
| | gltA | Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. (433 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa) |
| | glpX | Fructose 1,6-bisphosphatase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (356 aa) |
| | CCH86529.1 | Enoyl-CoA hydratase/isomerase; Function of strongly homologous gene; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (242 aa) |
| | CCH86530.1 | Dehydrogenase; Function of strongly homologous gene; enzyme. (324 aa) |
| | sdhB | Succinate dehydrogenase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (249 aa) |
| | sdhA | Succinate dehydrogenase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (648 aa) |
| | sdhC | Succinate dehydrogenase/fumarate reductase cytochrome b subunit, b558 family; Function of strongly homologous gene; enzyme. (236 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (237 aa) |
| | sir | Sulfite reductase [ferredoxin]; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (559 aa) |
| | dapD | Tetrahydrodipicolinate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (328 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Function of strongly homologous gene; enzyme. (373 aa) |
| | nthA | Fragment of Nitrile hydratase subunit beta (Nitrilase) (NHase) (part 2); Function of strongly homologous gene; enzyme. (196 aa) |
| | caiD | Carnitinyl-CoA dehydratase; Function of strongly homologous gene; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa) |
| | fdnI | Formate dehydrogenase gamma subunit; Function of strongly homologous gene; enzyme. (215 aa) |
| | CCH86799.1 | Glutaryl-CoA dehydrogenase; Function of strongly homologous gene; enzyme. (392 aa) |
| | CCH86823.1 | Aldo/keto reductase, NAD(P)-binding; Function of strongly homologous gene; enzyme. (298 aa) |
| | serB | Phosphoserine phosphatase; Function of strongly homologous gene; enzyme. (419 aa) |
| | gnd | 6-phosphogluconate dehydrogenase, decarboxylating 2; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (478 aa) |
| | CCH86866.1 | Putative aldo/keto reductase, NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (304 aa) |
| | dcaA | Acyl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (387 aa) |
| | CCH86882.1 | Gluconokinase; Function of strongly homologous gene; enzyme. (184 aa) |
| | CCH86900.1 | Acetyl/propionyl-CoA carboxylase, alpha subunit; Function of strongly homologous gene; enzyme. (666 aa) |
| | fbiC | FO synthase, 7, 8-didemethyl-8-hydroxy-5-deazariboflavin synthase; Function of strongly homologous gene; enzyme. (865 aa) |
| | pdxH-2 | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Function of strongly homologous gene; enzyme. (201 aa) |
| | CCH86935.1 | Methylenetetrahydrofolate reductase; Function of strongly homologous gene; enzyme; Belongs to the methylenetetrahydrofolate reductase family. (323 aa) |
| | zhuL | Enantiomer selective amidase. (494 aa) |
| | amdA-2 | Amidase; Function of strongly homologous gene; enzyme. (535 aa) |
| | amiB | Amidase amiB2; Function of strongly homologous gene; enzyme; Belongs to the amidase family. (476 aa) |
| | rpiB | Ribose-5-phosphate isomerase B; Function of strongly homologous gene; enzyme. (161 aa) |
| | CCH87098.1 | Putative coenzyme F390 synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (478 aa) |
| | CCH87101.1 | Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (455 aa) |
| | fmdA | Acetamidase/formamidase; Function of strongly homologous gene; enzyme. (340 aa) |
| | ACX | Acyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme. (408 aa) |
| | pccB | Propionyl-CoA carboxylase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (471 aa) |
| | aceE | Fragment of conserved protein of unknown function (part 1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (937 aa) |
| | glnA | Glutamine synthetase 2; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family. (446 aa) |
| | glnA-2 | Glutamine synthetase; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family. (725 aa) |
| | glnA-3 | Glutamine synthetase I (Glutamate--ammonia ligase I) (GSI); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (477 aa) |
| | fdh-2 | Formaldehyde dehydrogenase; Function of strongly homologous gene; enzyme. (384 aa) |
| | dehH | Haloacetate dehalogenase H-1; Function of strongly homologous gene; enzyme. (293 aa) |
| | CCH87483.1 | Flavin-containing monooxygenase; Function of strongly homologous gene; enzyme. (497 aa) |
| | CCH87525.1 | Dienelactone hydrolase-like enzyme; Function of strongly homologous gene; enzyme. (250 aa) |
| | CCH87564.1 | Putative secreted amidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (557 aa) |
| | gabD | Succinate-semialdehyde dehydrogenase [NADP+] 1; Function of strongly homologous gene; enzyme. (474 aa) |
| | CCH87611.1 | Putative Dihydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DapA family. (253 aa) |
| | CCH87647.1 | Aminotransferase; Function of strongly homologous gene; enzyme. (400 aa) |
| | xdhC-2 | Xanthine dehydrogenase, small subunit, 2Fe-2S ferredoxin, iron-sulphur binding; Function of strongly homologous gene; enzyme. (169 aa) |
| | xdhB | Xanthine dehydrogenase medium chain, FAD-binding; Function of strongly homologous gene; enzyme. (337 aa) |
| | xdhA-2 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein, molybdopterin binding; Function of strongly homologous gene; enzyme. (697 aa) |
| | CCH87677.1 | Putative dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (319 aa) |
| | CCH87684.1 | Glucose-6-phosphate 1-dehydrogenase. (434 aa) |
| | paaE | Phenylacetic acid degradation NADH oxidoreductase; Function of strongly homologous gene; enzyme. (358 aa) |
| | paaD | Phenylacetic acid degradation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (167 aa) |
| | paaC | Phenylacetic acid degradation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (297 aa) |
| | paaB | Phenylacetate-CoA oxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (121 aa) |
| | paaA | Phenylacetic acid degradation protein paaA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (321 aa) |
| | paaK | phenylacetyl-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (445 aa) |
| | paaZ | Fused aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (682 aa) |
| | CCH87760.1 | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (422 aa) |
| | gabD1 | Succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. (470 aa) |
| | ppsA | Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Function of strongly homologous gene; enzyme. (289 aa) |
| | talB | Transaldolase; Function of strongly homologous gene; enzyme. (371 aa) |
| | CCH87817.1 | Aryl-alcohol dehydrogenase; Function of strongly homologous gene; enzyme. (370 aa) |
| | CCH87820.1 | Putative phosphoglycerate mutase gpmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (218 aa) |
| | CCH87824.1 | Xanthine dehydrogenase FAD-binding subunit; Function of strongly homologous gene; enzyme. (284 aa) |
| | CCH87852.1 | Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Function of strongly homologous gene; enzyme. (251 aa) |
| | CCH87853.1 | Succinate dehydrogenase; Function of strongly homologous gene; enzyme. (598 aa) |
| | CCH87873.1 | NADP-dependent alcohol dehydrogenase; Function of strongly homologous gene; enzyme. (346 aa) |
| | phbB | Acetoacetyl-CoA reductase; Function of strongly homologous gene; enzyme. (271 aa) |
| | fahA-2 | Fumarylacetoacetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (408 aa) |
| | hmgA | Homogentisate 1,2-dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (401 aa) |
| | CCH87895.1 | Monooxygenase FAD-binding protein; Function of strongly homologous gene; enzyme. (529 aa) |
| | CCH87906.1 | Lipase/esterase; Function of strongly homologous gene; enzyme. (266 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (451 aa) |
| | CCH88052.1 | 2-keto-3-deoxy-L-rhamnonate aldolase; Function of strongly homologous gene; enzyme; Belongs to the HpcH/HpaI aldolase family. (223 aa) |
| | pps | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa) |
| | CCH88131.1 | Butyrate--CoA ligase; Function of strongly homologous gene; enzyme. (567 aa) |
| | CCH88164.1 | Homologs of previously reported genes of unknown function. (332 aa) |
| | CCH88165.1 | Homologs of previously reported genes of unknown function. (317 aa) |
| | CCH88254.1 | 4-oxalomesaconate hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (339 aa) |
| | pheB | Metapyrocatechase; Function of strongly homologous gene; enzyme. (334 aa) |
| | CCH88257.1 | Homologs of previously reported genes of unknown function. (358 aa) |
| | ligK | 4-carboxy-4-hydroxy-2-oxoadipate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (233 aa) |
| | gcvT | Aminomethyltransferase; Function of strongly homologous gene; enzyme; Belongs to the GcvT family. (468 aa) |
| | gcvT-2 | Aminomethyltransferase; Function of strongly homologous gene; enzyme; Belongs to the GcvT family. (453 aa) |
| | ligB-2 | Protocatechuate 4,5-dioxygenase, beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (285 aa) |
| | ligA | Protocatechuate 4,5-dioxygenase, alpha chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (121 aa) |
| | catC | Muconolactone Delta-isomerase; Function of strongly homologous gene; enzyme. (92 aa) |
| | CCH88279.1 | 5,10-methylenetetrahydrofolate reductase; Function of strongly homologous gene; enzyme; Belongs to the methylenetetrahydrofolate reductase family. (306 aa) |
| | folD | Bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | xylB | Aryl-alcohol dehydrogenase; Function of strongly homologous gene; enzyme. (378 aa) |
| | CCH88287.1 | Glycine cleavage T protein (Aminomethyl transferase); Function of strongly homologous gene; enzyme; Belongs to the GcvT family. (266 aa) |
| | aceA | Isocitrate lyase; Function of strongly homologous gene; enzyme. (435 aa) |
| | aceB | Malate synthase; Function of strongly homologous gene; enzyme. (548 aa) |
| | hcaC | 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit; Function of strongly homologous gene; enzyme. (106 aa) |
| | CCH88336.1 | Transketolase C-terminal section; Function of strongly homologous gene; enzyme. (326 aa) |
| | CCH88337.1 | Transketolase N-terminal section (TK); Function of strongly homologous gene; enzyme. (292 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (620 aa) |
| | CCH88351.1 | Aldehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (492 aa) |
| | vaoA | Vanillyl-alcohol oxidase; Function of strongly homologous gene; enzyme. (529 aa) |
| | CCH88384.1 | Phenol 2-monooxygenase; Function of strongly homologous gene; enzyme. (642 aa) |
| | CCH88406.1 | Phenol 2-monooxygenase; Function of strongly homologous gene; enzyme. (642 aa) |
| | CCH88419.1 | Putative monooxygenase FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (375 aa) |
| | CCH88461.1 | Glucose-6-phosphate 1-dehydrogenase; Function of strongly homologous gene; enzyme. (478 aa) |
| | CCH88479.1 | Carbohydrate kinase; Function of strongly homologous gene; enzyme; Belongs to the FGGY kinase family. (500 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (428 aa) |
| | CCH88502.1 | Pyruvate carboxylase (fragment); Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1117 aa) |
| | CCH88571.1 | Aldose 1-epimerase; Function of strongly homologous gene; enzyme. (305 aa) |
| | argD | Acetylornithine transaminase (NAcOATase and DapATase), PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (394 aa) |
| | CCH88643.1 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. (393 aa) |
| | nasD | Rieske (2Fe-2S) iron-sulphur domain protein; Function of strongly homologous gene; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (846 aa) |
| | nasC | Assimilatory nitrate reductase catalytic subunit; Function of strongly homologous gene; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (851 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Function of strongly homologous gene; enzyme; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa) |
| | CCH88796.1 | Putative Extradiol ring-cleavage dioxygenase class III protein subunit B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (253 aa) |
| | citA-2 | Citrate synthase; Function of strongly homologous gene; enzyme. (323 aa) |
| | pyk | Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family. (471 aa) |
| | gltD | Glutamate synthase [NADPH] small chain, (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (495 aa) |
| | gltB | Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1561 aa) |
| | mqo | Malate:quinone oxidoreductase; Function of strongly homologous gene; enzyme. (484 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family. (307 aa) |
| | ltaA | L-allo-threonine aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (348 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa) |
| | glcK | Glucokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (333 aa) |
| | bfmBC | Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (459 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Function of strongly homologous gene; enzyme. (623 aa) |
| | acnA | Aconitate hydratase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (963 aa) |
| | CCH89006.1 | Putative thiosulfate sulfurtransferase sseB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (274 aa) |
| | sufE | Ferredoxin containing [2Fe-2S] Rieske domain; Function of strongly homologous gene; carrier. (118 aa) |
| | tkt | Transketolase; Function of strongly homologous gene; enzyme; Belongs to the transketolase family. (743 aa) |
| | tal | Transaldolase subfamily; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (368 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (505 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (270 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (269 aa) |
| | pgk | Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | amiB-2 | Amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit; Function of strongly homologous gene; enzyme. (390 aa) |
| | fdh-6 | Formaldehyde dehydrogenase; Function of strongly homologous gene; enzyme. (393 aa) |
| | CCH89292.1 | Putative maleate cis-trans isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (244 aa) |
| | CCH89298.1 | Putative carboxymethylenebutenolidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (259 aa) |
| | fadA-3 | 3-ketoacyl-CoA thiolase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa) |
| | ppgK | Polyphosphate glucokinase; Function of strongly homologous gene; enzyme. (247 aa) |
| | glnA-4 | Glutamine synthetase; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family. (464 aa) |
| | CCH89399.1 | Putative (S)-2-haloacid dehalogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (324 aa) |
| | phbA | acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa) |
| | CCH89416.1 | Methylaspartate ammonia-lyase; Function of strongly homologous gene; enzyme. (420 aa) |
| | CCH89452.1 | Isochorismatase hydrolase; Function of strongly homologous gene; enzyme. (201 aa) |
| | CCH89457.1 | Putative isocitrate lyase-family protein, Putative carboxyvinyl-carboxyphosphonate phosphorylmutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (296 aa) |
| | CCH89604.1 | Putative Alpha/beta hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (273 aa) |
| | CCH89662.1 | Aldehyde dehydrogenase [NAD+]; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (486 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (299 aa) |
| | pgi | Glucose-6-phosphate isomerase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family. (542 aa) |
| | dapA | Dihydrodipicolinate synthase 1; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa) |
| | CCH89757.1 | Phosphoesterase; Function of strongly homologous gene; enzyme. (336 aa) |
| | CCH89820.1 | Acylphosphatase; Function of strongly homologous gene; enzyme. (90 aa) |
| | cofC | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. (220 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (497 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (537 aa) |
| | CCH89886.1 | Cysteine synthase; Function of strongly homologous gene; enzyme. (369 aa) |
| | CCH89903.1 | acetyl-CoA acetyltransferase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa) |
| | mce | Methylmalonyl-CoA epimerase; Function of strongly homologous gene; enzyme. (149 aa) |
| | CCH89910.1 | 3-hydroxyacyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme. (554 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (435 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | thrC-2 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (361 aa) |
| | hom | Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (432 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (493 aa) |
| | sucA | 2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme. (1275 aa) |
| | gyaR | Glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa) |
| | CCH89967.1 | Pyruvate carboxylase; Function of strongly homologous gene; enzyme. (74 aa) |
| | CCH89975.1 | Succinate-semialdehyde dehydrogenase [NADP+]; Function of strongly homologous gene; enzyme. (488 aa) |
| | cofD | LPPG:FO 2-phospho-L-lactate transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (316 aa) |
| | CCH90084.1 | F420-dependent oxidoreductase; Function of strongly homologous gene; enzyme. (355 aa) |
| | CCH90146.1 | Putative propionyl-CoA carboxylase beta chain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (542 aa) |
| | bccA | Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Biotin carboxylase; Function of strongly homologous gene; enzyme. (587 aa) |
| | mutB | Methylmalonyl-CoA mutase large subunit (MCM-alpha); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (736 aa) |
| | mutA | Methylmalonyl-CoA mutase small subunit (MCM-beta); Function of strongly homologous gene; enzyme. (640 aa) |
| | ald-2 | Aldehyde dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (480 aa) |
| | icd | Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (317 aa) |
| | folD-2 | Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (289 aa) |
| | sucD-2 | succinyl-CoA synthetase, alpha subunit, NAD(P)-binding; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa) |
| | sucC | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa) |
| | korA | 2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme. (667 aa) |
| | korB | 2-oxoacid:ferredoxin oxidoreductase, beta subunit; Function of strongly homologous gene; enzyme. (370 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase; Function of strongly homologous gene; enzyme. (455 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Function of strongly homologous gene; enzyme; Belongs to the ALAD family. (331 aa) |
| | hemD | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. (517 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (313 aa) |
| | hemA-2 | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (462 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (250 aa) |
| | cysA-2 | Thiosulfate sulfurtransferase; Function of strongly homologous gene; enzyme. (277 aa) |
| | cysD | Sulfate adenylate transferase, subunit 2 (NodP-like); Function of strongly homologous gene; enzyme. (302 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (435 aa) |
| | CCH90462.1 | Putative enoyl-CoA hydratase echA14; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (249 aa) |
| | pcaC | 4-carboxymuconolactone decarboxylase; Function of strongly homologous gene; enzyme. (138 aa) |
| | pcaD | 3-oxoadipate enol-lactonase; Function of strongly homologous gene; enzyme. (259 aa) |
| | pcaB | 3-carboxy-cis,cis-muconate cycloisomerase; Function of strongly homologous gene; enzyme. (443 aa) |
| | pcaG | Protocatechuate 3,4-dioxygenase alpha chain; Function of strongly homologous gene; enzyme. (227 aa) |
| | pcaH | Protocatechuate 3,4-dioxygenase beta chain; Function of strongly homologous gene; enzyme. (255 aa) |
| | pobA | P-hydroxybenzoate hydroxylase; Function of strongly homologous gene; enzyme. (389 aa) |
| | fba | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (342 aa) |
| | glcD | Glycolate oxidase subunit; Function of strongly homologous gene; enzyme. (474 aa) |
| | CCH90543.1 | Serine-glyoxylate aminotransferase; Function of strongly homologous gene; enzyme. (390 aa) |
| | aceB-2 | Malate synthase; Function of strongly homologous gene; enzyme; Belongs to the malate synthase family. (533 aa) |
| | glcD-2 | Glycolate oxidase, subunit GlcD; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (518 aa) |
| | glcE | Glycolate oxidase FAD binding subunit; Function of strongly homologous gene; enzyme. (422 aa) |
| | glcF | Glycolate oxidase iron-sulfur subunit; Function of strongly homologous gene; enzyme. (466 aa) |
| | CCH90576.1 | Zinc-type alcohol dehydrogenase-like protein yycR; Function of strongly homologous gene; enzyme. (413 aa) |
| | CCH90608.1 | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. (704 aa) |
| | pdhC | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of strongly homologous gene; enzyme. (499 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (325 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (378 aa) |
| | CCH90637.1 | Acetyl-CoA acetyltransferase with thiolase domain; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (379 aa) |
| | pckG-2 | Phosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (604 aa) |
| | pyc-2 | Pyruvate carboxylase (fragment); Function of strongly homologous gene; enzyme. (911 aa) |
| | CCH90709.1 | Putative phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the phosphoglycerate mutase family. (249 aa) |
| | glyA-3 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (477 aa) |
| | CCH90737.1 | Haloacid dehalogenase superfamily enzyme, subfamily IA; Function of strongly homologous gene; enzyme. (223 aa) |
| | CCH90779.1 | Monooxygenase, FAD-binding; Function of strongly homologous gene; enzyme. (467 aa) |
| | CCH90794.1 | Putative oxidoreductase, Zn-dependent and NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (348 aa) |
| | CCH90814.1 | Putative 5,10-methylenetetrahydromethanopterin reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (331 aa) |
| | rhaB | Carbohydrate kinase; Function of strongly homologous gene; enzyme. (500 aa) |
| | rhaB-2 | Rhamnulokinase; Function of strongly homologous gene; enzyme. (477 aa) |
| | rhaA | L-rhamnose isomerase; Function of strongly homologous gene; enzyme. (389 aa) |
| | CCH90871.1 | Amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit; Function of strongly homologous gene; enzyme; Belongs to the amidase family. (471 aa) |
| | gdh | Glutamate dehydrogenase (NAD); Function of strongly homologous gene; enzyme. (1639 aa) |
| | argE | Acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase; Function of strongly homologous gene; enzyme. (357 aa) |
| | pgm | Phosphomannomutase/phosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (544 aa) |
