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| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (342 aa) |
| | CCH85652.1 | Histidinol phosphate phosphatase HisJ family; Function of strongly homologous gene; enzyme; Belongs to the PHP hydrolase family. HisK subfamily. (275 aa) |
| | CCH85682.1 | Cysteine-S-conjugate beta-lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (395 aa) |
| | pheA | Prephenate dehydratase; Function of strongly homologous gene; enzyme. (319 aa) |
| | CCH85999.1 | Prephenate dehydrogenase; Function of strongly homologous gene; enzyme. (305 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (577 aa) |
| | ask | Aspartokinase; Function of strongly homologous gene; enzyme; Belongs to the aspartokinase family. (421 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa) |
| | CCH86076.1 | Putative Threonine-phosphate decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (534 aa) |
| | CCH86128.1 | Phosphoglycerate mutase; Function of strongly homologous gene; enzyme; Belongs to the phosphoglycerate mutase family. (188 aa) |
| | thrC | L-threonine synthase; Function of strongly homologous gene; enzyme. (433 aa) |
| | CCH86316.1 | Asparagine synthetase [glutamine-hydrolyzing]; Function of strongly homologous gene; enzyme. (594 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (371 aa) |
| | citA | Citrate synthase 2; Function of strongly homologous gene; enzyme; Belongs to the citrate synthase family. (376 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | eno | Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | CCH86438.1 | L-threonine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (408 aa) |
| | gltA | Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. (433 aa) |
| | CCH86587.1 | GCN5-related N-acetyltransferase. (250 aa) |
| | dapD | Tetrahydrodipicolinate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (328 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Function of strongly homologous gene; enzyme. (373 aa) |
| | CCH86655.1 | Putative thiamine pyrophosphate-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (513 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Function of strongly homologous gene; enzyme. (344 aa) |
| | serB | Phosphoserine phosphatase; Function of strongly homologous gene; enzyme. (419 aa) |
| | rpiB | Ribose-5-phosphate isomerase B; Function of strongly homologous gene; enzyme. (161 aa) |
| | proB | Gamma-glutamate kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (361 aa) |
| | proA | Gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa) |
| | glnA | Glutamine synthetase 2; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family. (446 aa) |
| | glnA-2 | Glutamine synthetase; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family. (725 aa) |
| | glnA-3 | Glutamine synthetase I (Glutamate--ammonia ligase I) (GSI); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (477 aa) |
| | aroG | Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (413 aa) |
| | CCH87611.1 | Putative Dihydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DapA family. (253 aa) |
| | CCH87647.1 | Aminotransferase; Function of strongly homologous gene; enzyme. (400 aa) |
| | talB | Transaldolase; Function of strongly homologous gene; enzyme. (371 aa) |
| | CCH87820.1 | Putative phosphoglycerate mutase gpmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (218 aa) |
| | argG | Argininosuccinate synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (482 aa) |
| | metH | B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1271 aa) |
| | sdaA | L-serine dehydratase; Function of strongly homologous gene; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa) |
| | CCH88336.1 | Transketolase C-terminal section; Function of strongly homologous gene; enzyme. (326 aa) |
| | CCH88337.1 | Transketolase N-terminal section (TK); Function of strongly homologous gene; enzyme. (292 aa) |
| | aroQ | 3-dehydroquinate dehydratase 1; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (152 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (327 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (428 aa) |
| | sdaA-2 | L-serine ammonia-lyase; Function of strongly homologous gene; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (456 aa) |
| | CCH88502.1 | Pyruvate carboxylase (fragment); Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1117 aa) |
| | CCH88570.1 | Chorismate mutase; Function of strongly homologous gene; enzyme. (109 aa) |
| | CCH88587.1 | Arginase; Function of strongly homologous gene; enzyme; Belongs to the arginase family. (244 aa) |
| | argH | Argininosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (480 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (315 aa) |
| | argD | Acetylornithine transaminase (NAcOATase and DapATase), PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (394 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (330 aa) |
| | argJ | Bifunctional protein argJ [Includes: Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (383 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (346 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (288 aa) |
| | hisE | Phosphoribosyl-ATP pyrophosphatase; Function of strongly homologous gene; enzyme; Belongs to the PRA-PH family. (87 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Function of strongly homologous gene; enzyme; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa) |
| | metK | Methionine adenosyltransferase 1 (AdoMet synthetase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (407 aa) |
| | aroQ-2 | 3-dehydroquinate dehydratase type 2; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (354 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (176 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (392 aa) |
| | aroE-2 | Shikimate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the shikimate dehydrogenase family. (274 aa) |
| | citA-2 | Citrate synthase; Function of strongly homologous gene; enzyme. (323 aa) |
| | pyk | Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family. (471 aa) |
| | gltD | Glutamate synthase [NADPH] small chain, (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (495 aa) |
| | gltB | Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1561 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (292 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (464 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the TrpC family. (269 aa) |
| | trpE | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (501 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (124 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (264 aa) |
| | priA-2 | Phosphoribosyl isomerase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (243 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH,glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (203 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Function of strongly homologous gene; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (373 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa) |
| | ltaA | L-allo-threonine aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (348 aa) |
| | aroF | Phospho-2-dehydro-3-deoxyheptonate aldolase; Function of strongly homologous gene; enzyme; Belongs to the class-II DAHP synthase family. (445 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (352 aa) |
| | asnB | Asparagine synthetase [glutamine-hydrolyzing]; Function of strongly homologous gene; enzyme. (644 aa) |
| | acnA | Aconitate hydratase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (963 aa) |
| | tkt | Transketolase; Function of strongly homologous gene; enzyme; Belongs to the transketolase family. (743 aa) |
| | tal | Transaldolase subfamily; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (368 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (269 aa) |
| | pgk | Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | glnA-4 | Glutamine synthetase; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family. (464 aa) |
| | CCH89649.1 | Putative methionine synthase II (Cobalamin-independent); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (374 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (299 aa) |
| | dapA | Dihydrodipicolinate synthase 1; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa) |
| | ilvE | Branched-chain amino acid aminotransferase protein (BCAT); Function of strongly homologous gene; enzyme. (382 aa) |
| | CCH89838.1 | Putative cystathionine gamma-lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (384 aa) |
| | leuD | 3-isopropylmalate dehydratase (small subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuC | 3-isopropylmalate dehydratase (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (470 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the alpha-IPM synthase/homocitrate synthase family. (545 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (339 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (537 aa) |
| | ilvC | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa) |
| | ilvH | Acetolactate synthase small subunit (AHAS) (Acetohydroxy-acid synthase small subunit) (ALS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (176 aa) |
| | ilvI | Acetolactate synthase large subunit (AHAS) (Acetohydroxy-acid synthase large subunit) (ALS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (648 aa) |
| | ilvD | Dihydroxy-acid dehydratase (DAD); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family. (570 aa) |
| | CCH89886.1 | Cysteine synthase; Function of strongly homologous gene; enzyme. (369 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (435 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | thrC-2 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (361 aa) |
| | hom | Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (432 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (493 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (429 aa) |
| | CCH89981.1 | Inositol-phosphate phosphatase; Function of strongly homologous gene; enzyme. (272 aa) |
| | cbs | Cystathionine beta-synthase; Function of strongly homologous gene; enzyme. (464 aa) |
| | metB | Cystathionine gamma-synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (387 aa) |
| | CCH90170.1 | Putative deacetylase/succinyl-diaminopimelate desuccinylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (423 aa) |
| | hisC-2 | Histidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (374 aa) |
| | icd | Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa) |
| | CCH90223.1 | Monofunctional chorismate mutase; Function of strongly homologous gene; enzyme. (92 aa) |
| | asp | Aspartate aminotransferase; Function of strongly homologous gene; enzyme. (419 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (250 aa) |
| | CCH90471.1 | Putative Acetylornithine deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (427 aa) |
| | fba | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (342 aa) |
| | pyc-2 | Pyruvate carboxylase (fragment); Function of strongly homologous gene; enzyme. (911 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (419 aa) |
| | metX | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (348 aa) |
| | CCH90709.1 | Putative phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the phosphoglycerate mutase family. (249 aa) |
| | glyA-3 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (477 aa) |
| | CCH90803.1 | Putative L-serine ammonia-lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (313 aa) |
| | argE | Acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase; Function of strongly homologous gene; enzyme. (357 aa) |
