STRINGSTRING
ndk ndk tuf tuf secE secE rpoB rpoB rpoC rpoC tuf-2 tuf-2 secY secY rpoA rpoA Daud_0307 Daud_0307 Daud_0386 Daud_0386 Daud_0387 Daud_0387 Daud_0391 Daud_0391 Daud_0462 Daud_0462 Daud_0476 Daud_0476 Daud_0559 Daud_0559 Daud_0623 Daud_0623 Daud_0921 Daud_0921 Daud_1059 Daud_1059 Daud_1139 Daud_1139 Daud_1161 Daud_1161 Daud_1164 Daud_1164 Daud_1308 Daud_1308 Daud_1341 Daud_1341 Daud_1342 Daud_1342 secF secF secD secD Daud_1402 Daud_1402 Daud_1564 Daud_1564 rpoZ rpoZ Daud_1956 Daud_1956 Daud_1967 Daud_1967 Daud_1982 Daud_1982 Daud_2034 Daud_2034 secA secA Daud_2149 Daud_2149 Daud_2183 Daud_2183
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (150 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (113 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1154 aa)
tuf-2Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (400 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (424 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (315 aa)
Daud_0307Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (76 aa)
Daud_0386PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bld:BLi02528 putative oligopeptide ABC transporter (permease); RBL00341. (312 aa)
Daud_0387PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mac:MA0880 dipeptide ABC transporter, dipeptide-binding protein. (309 aa)
Daud_0391PFAM: extracellular solute-binding protein, family 5; KEGG: mac:MA3048 oligopeptide ABC transporter, solute-binding protein. (522 aa)
Daud_0462KEGG: swo:Swol_2460 hypothetical protein. (98 aa)
Daud_0476PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1; KEGG: mta:Moth_1000 hypothetical protein. (474 aa)
Daud_0559TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: pca:Pcar_0114 thioredoxin reductase (NADPH). (304 aa)
Daud_0623Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (372 aa)
Daud_0921TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pca:Pcar_3068 thioredoxin; Belongs to the thioredoxin family. (107 aa)
Daud_1059Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (197 aa)
Daud_1139Thioredoxin-disulfide reductase; PFAM: glucose-inhibited division protein A; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dsy:DSY1359 hypothetical protein. (293 aa)
Daud_1161KEGG: tte:TTE2532 predicted Zn-dependent hydrolase of the beta-lactamase fold. (228 aa)
Daud_1164KEGG: gvi:glr0116 hypothetical protein. (213 aa)
Daud_1308PFAM: major facilitator superfamily MFS_1; KEGG: bsu:BG13112 similar to multidrug resistance protein. (404 aa)
Daud_1341KEGG: mta:Moth_2197 putative transcriptional regulator, AsnC family. (155 aa)
Daud_1342KEGG: mta:Moth_2198 putative transcriptional regulator, AsnC family. (157 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (293 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (410 aa)
Daud_1402KEGG: mbo:Mb0630c hypothetical protein. (454 aa)
Daud_1564PFAM: major facilitator superfamily MFS_1; KEGG: gsu:GSU2491 major facilitator family transporter. (400 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (69 aa)
Daud_1956TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: mth:MTH1727 phosphate transport system substrate-binding protein. (283 aa)
Daud_1967PFAM: CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit; KEGG: aae:aq_1166 hypothetical protein. (205 aa)
Daud_1982PFAM: extracellular solute-binding protein, family 5; KEGG: dsy:DSY0502 hypothetical protein. (508 aa)
Daud_2034PFAM: major facilitator superfamily MFS_1; KEGG: dsy:DSY3748 hypothetical protein. (386 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (903 aa)
Daud_2149PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: sth:STH76 low molecular weight protein-tyrosine-phosphatase. (157 aa)
Daud_2183PFAM: regulatory protein, AsnC/Lrp family; KEGG: chy:CHY_0114 transcriptional regulator, AsnC family. (162 aa)
Your Current Organism:
Desulforudis audaxviator
NCBI taxonomy Id: 477974
Other names: C. Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator str. MP104C, Candidatus Desulforudis audaxviator strain MP104C
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