STRINGSTRING
clpX clpX dnaA dnaA mnmE mnmE Daud_2211 Daud_2211 rho rho atpD atpD Daud_2041 Daud_2041 Daud_1858 Daud_1858 Daud_1762 Daud_1762 Daud_1546 Daud_1546 pstB-2 pstB-2 Daud_1495 Daud_1495 Daud_1492 Daud_1492 Daud_1477 Daud_1477 lon lon pstB pstB recD2-2 recD2-2 Daud_1389 Daud_1389 Daud_1388 Daud_1388 Daud_1371 Daud_1371 ruvB ruvB Daud_1315 Daud_1315 Daud_1259 Daud_1259 Daud_1214 Daud_1214 Daud_1213 Daud_1213 Daud_1209 Daud_1209 Daud_1208 Daud_1208 Daud_1207 Daud_1207 der der Daud_1150 Daud_1150 Daud_1145 Daud_1145 Daud_1137 Daud_1137 Daud_1128 Daud_1128 Daud_1127 Daud_1127 Daud_1126 Daud_1126 Daud_1031 Daud_1031 Daud_1007 Daud_1007 Daud_0991 Daud_0991 Daud_0969 Daud_0969 Daud_0968 Daud_0968 Daud_0956 Daud_0956 Daud_0951 Daud_0951 Daud_0893 Daud_0893 recA recA Daud_0841 Daud_0841 Daud_0837 Daud_0837 Daud_0820 Daud_0820 recD2 recD2 Daud_0689 Daud_0689 Daud_0672 Daud_0672 Daud_0671 Daud_0671 hslU hslU Daud_0533 Daud_0533 clpB clpB Daud_0412 Daud_0412 Daud_0389 Daud_0389 Daud_0388 Daud_0388 uvrA uvrA ftsE ftsE Daud_0275 Daud_0275 radA radA Daud_0181 Daud_0181 ftsH ftsH dnaX dnaX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (417 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (445 aa)
mnmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (461 aa)
Daud_2211Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (442 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (492 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (472 aa)
Daud_2041PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: chy:CHY_2201 ATPase, AAA family. (435 aa)
Daud_1858Cobalt ABC transporter, ATPase subunit; KEGG: mta:Moth_1219 cobalt transport protein ATP-binding subunit; TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; Precorrin-8X methylmutase CbiC/CobH; SMART: AAA ATPase. (541 aa)
Daud_1762Flagellar protein export ATPase FliI; KEGG: mta:Moth_0774 ATPase FliI/YscN; TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase. (454 aa)
Daud_1546PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bcl:ABC1702 metal ion ABC transporter ATP-binding protein. (248 aa)
pstB-2ABC transporter related; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (244 aa)
Daud_1495KEGG: plt:Plut_0692 ATPase; TIGRFAM: gas vesicle protein GvpN; PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. (304 aa)
Daud_1492KEGG: plt:Plut_0697 AAA ATPase, CDC48; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; Belongs to the AAA ATPase family. (753 aa)
Daud_1477Peptidase S16, lon domain protein; PFAM: magnesium chelatase, ChlI subunit; AAA ATPase, central domain protein; peptidase S16, lon domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: dsy:DSY3196 hypothetical protein. (563 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (797 aa)
pstBPhosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (251 aa)
recD2-2Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (719 aa)
Daud_1389PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sth:STH824 branched chain amino acid ABC transporter ATP-binding protein. (256 aa)
Daud_1388PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mta:Moth_2498 ABC transporter related. (236 aa)
Daud_1371PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: det:DET0815 FeS assembly ATPase SufC, putative. (251 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (344 aa)
Daud_1315PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sth:STH1933 iron ABC transporter ATP-binding protein. (267 aa)
Daud_1259SMART: AAA ATPase; KEGG: pai:PAE0090 hypothetical protein. (412 aa)
Daud_1214PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mba:Mbar_A2397 iron(III) ABC transporter, ATP-binding protein. (274 aa)
Daud_1213PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cyb:CYB_2030 ABC transporter, ATP-binding protein. (309 aa)
Daud_1209KEGG: mba:Mbar_A1776 magnesium-chelatase subunit; PFAM: magnesium chelatase, ChlI subunit; von Willebrand factor, type A; SMART: AAA ATPase. (670 aa)
Daud_1208KEGG: mba:Mbar_A1776 magnesium-chelatase subunit; PFAM: magnesium chelatase, ChlI subunit; SMART: AAA ATPase. (372 aa)
Daud_1207KEGG: cyb:CYB_2030 ABC transporter, ATP-binding protein; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase. (279 aa)
derSmall GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (438 aa)
Daud_1150PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dvu:DVU0103 cation ABC transporter, ATP-binding protein, putative. (272 aa)
Daud_1145PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: swo:Swol_1715 ATPase. (236 aa)
Daud_1137PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mta:Moth_1128 ABC transporter related. (240 aa)
Daud_1128PFAM: ABC transporter related; KEGG: gsu:GSU3392 branched-chain amino acid ABC transporter, ATP-binding protein. (256 aa)
Daud_1127PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: chy:CHY_2228 high affinity branched-chain amino acid ABC transporter, ATP-binding protein. (235 aa)
Daud_1126KEGG: mta:Moth_2297 daunorubicin resistance ABC transporter ATP-binding subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase. (326 aa)
Daud_1031DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (572 aa)
Daud_1007SMART: AAA ATPase; KEGG: sth:STH1862 stage III sporulation protein AA. (332 aa)
Daud_0991PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; SMART: AAA ATPase; KEGG: chy:CHY_0630 type IV pilus assembly protein PilB. (564 aa)
Daud_0969Twitching motility protein; KEGG: chy:CHY_0631 type IV pilus retraction protein PilT; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase. (365 aa)
Daud_0968PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; SMART: AAA ATPase; KEGG: mta:Moth_1554 type II secretion system protein E. (561 aa)
Daud_0956PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: mta:Moth_1554 type II secretion system protein E. (561 aa)
Daud_0951KEGG: rxy:Rxyl_1165 twitching motility protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase. (372 aa)
Daud_0893PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: mta:Moth_1184 IstB-like ATP-binding protein. (241 aa)
recArecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (345 aa)
Daud_0841Vesicle-fusing ATPase; KEGG: tte:TTE0122 ATP-dependent Zn proteases; PFAM: peptidase M41; AAA ATPase, central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family. (491 aa)
Daud_0837PFAM: cell divisionFtsK/SpoIIIE; KEGG: mta:Moth_1072 cell division FtsK/SpoIIIE. (727 aa)
Daud_0820Mg chelatase, subunit ChlI; KEGG: gsu:GSU0489 Mg chelatase-related protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; SMART: AAA ATPase. (514 aa)
recD2Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (688 aa)
Daud_0689Putative circadian clock protein, KaiC; PFAM: KaiC domain protein; SMART: AAA ATPase; KEGG: chy:CHY_0885 hypothetical protein. (467 aa)
Daud_0672PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: gka:GK3022 branched chain amino acid ABC transporter (ATP-binding protein). (239 aa)
Daud_0671PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tth:TTC0969 branched-chain amino acid transport ATP-binding protein livG. (252 aa)
hslUHeat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (464 aa)
Daud_0533PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cte:CT1092 ABC transporter, ATP-binding protein. (226 aa)
clpBATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (862 aa)
Daud_0412PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dsy:DSY3396 hypothetical protein. (219 aa)
Daud_0389Oligopeptide/dipeptide ABC transporter, ATPase subunit; KEGG: bja:blr1357 peptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (321 aa)
Daud_0388Oligopeptide/dipeptide ABC transporter, ATPase subunit; KEGG: sth:STH2824 oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (324 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (946 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
Daud_0275Cobalt ABC transporter, ATPase subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. (270 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (445 aa)
Daud_0181PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: chy:CHY_2348 negative regulator of genetic competence ClpC/MecB; Belongs to the ClpA/ClpB family. (812 aa)
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (620 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (447 aa)
Your Current Organism:
Desulforudis audaxviator
NCBI taxonomy Id: 477974
Other names: C. Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator str. MP104C, Candidatus Desulforudis audaxviator strain MP104C
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.