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Daud_0012 Daud_0012 Daud_0092 Daud_0092 Daud_0104 Daud_0104 Daud_0105 Daud_0105 Daud_0106 Daud_0106 Daud_0111 Daud_0111 Daud_0112 Daud_0112 Daud_0114 Daud_0114 Daud_0115 Daud_0115 Daud_0134 Daud_0134 gpmI gpmI eno eno Daud_0369 Daud_0369 Daud_0563 Daud_0563 Daud_0564 Daud_0564 Daud_0565 Daud_0565 Daud_0566 Daud_0566 Daud_0567 Daud_0567 ppcA ppcA Daud_0825 Daud_0825 Daud_0870 Daud_0870 Daud_0872 Daud_0872 Daud_0875 Daud_0875 Daud_0877 Daud_0877 Daud_0878 Daud_0878 Daud_1043 Daud_1043 pfkA pfkA Daud_1058 Daud_1058 Daud_1104 Daud_1104 pfkA-2 pfkA-2 mdh mdh Daud_1251 Daud_1251 Daud_1309 Daud_1309 acsA acsA Daud_1579 Daud_1579 Daud_1580 Daud_1580 Daud_1581 Daud_1581 Daud_1651 Daud_1651 Daud_1652 Daud_1652 Daud_1653 Daud_1653 fbp fbp Daud_1881 Daud_1881 Daud_1941 Daud_1941 Daud_1946 Daud_1946 Daud_1961 Daud_1961 Daud_1962 Daud_1962 Daud_1963 Daud_1963 Daud_1964 Daud_1964 Daud_1965 Daud_1965 Daud_1966 Daud_1966 glyA glyA Daud_2175 Daud_2175
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Daud_0012TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: chy:CHY_2698 D-3-phosphoglycerate dehydrogenase. (526 aa)
Daud_0092PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: gme:Gmet_2084 4Fe-4S ferredoxin, iron-sulfur binding protein. (1013 aa)
Daud_0104TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: chy:CHY_0733 NAD-dependent formate dehydrogenase, alpha subunit, selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (724 aa)
Daud_0105KEGG: mth:MTH1708 carbon monoxide dehydrogenase, alpha subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Prismane. (766 aa)
Daud_0106TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; PFAM: CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit; KEGG: mmp:MMP0984 CO dehydrogenase beta subunit/acetyl-CoA synthase subunit epsilon. (184 aa)
Daud_0111KEGG: mja:MJ0156 acetyl-CoA decarbonylase/synthase, subunit beta; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit. (399 aa)
Daud_0112PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; Fe-S cluster domain protein; KEGG: det:DET0699 corrinoid/iron-sulfur protein, large subunit. (452 aa)
Daud_0114KEGG: det:DET0701 corrinoid/iron-sulfur protein, small subunit. (298 aa)
Daud_0115PFAM: methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mta:Moth_1193 methyl-viologen-reducing hydrogenase, delta subunit. (173 aa)
Daud_0134PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mac:MA2963 iron-sulfur cluster binding protein. (161 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
Daud_0369PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_0098 formate dehydrogenase, beta subunit. (248 aa)
Daud_0563KEGG: chy:CHY_0927 putative heterodisulfide reductase, C subunit. (211 aa)
Daud_0564CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: chy:CHY_0929 putative succinate dehydrogenase, subunit C. (283 aa)
Daud_0565PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD dependent oxidoreductase; KEGG: chy:CHY_0930 heterodisulfide reductase, subunit A, selenocysteine-containing. (661 aa)
Daud_0566PFAM: methyl-viologen-reducing hydrogenase, delta subunit; KEGG: chy:CHY_0931 hydrogenase, methyl-violgen-reducing type, delta subunit, selenocysteine-containing. (144 aa)
Daud_0567PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: chy:CHY_0932 putative dehydrogenase, beta subunit. (328 aa)
ppcAProtein of unknown function DUF557; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (489 aa)
Daud_0825TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); phosphoserine phosphatase-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mth:MTH1626 phosphoserine phosphatase. (225 aa)
Daud_0870KEGG: mma:MM0121 carbon monoxide dehydrogenase; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane. (628 aa)
Daud_0872PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; Fe-S cluster domain protein; KEGG: chy:CHY_1223 acetyl-CoA decarbonylase/synthase complex subunit gamma. (443 aa)
Daud_0875PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; KEGG: chy:CHY_1226 acetyl-CoA decarbonylase/synthase complex subunit delta. (326 aa)
Daud_0877PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gme:Gmet_2084 4Fe-4S ferredoxin, iron-sulfur binding protein. (995 aa)
Daud_0878PFAM: methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mta:Moth_1193 methyl-viologen-reducing hydrogenase, delta subunit. (145 aa)
Daud_1043PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sth:STH2600 formate dehydrogenase beta subunit. (280 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
Daud_1058Proposed homoserine kinase; KEGG: pca:Pcar_1514 cofactor-independent phosphoglycerate mutase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; proposed homoserine kinase; PFAM: metalloenzyme domain protein. (405 aa)
Daud_1104PFAM: formylmethanofuran dehydrogenase, subunit E region; KEGG: mta:Moth_1467 formylmethanofuran dehydrogenase, subunit E region. (197 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (370 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)
Daud_1251CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: chy:CHY_0929 putative succinate dehydrogenase, subunit C. (282 aa)
Daud_1309PFAM: (2R)-phospho-3-sulfolactate synthase, ComA; KEGG: mta:Moth_0118 (2R)-phospho-3-sulfolactate synthase, ComA. (262 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
Daud_1579PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sth:STH2600 formate dehydrogenase beta subunit. (262 aa)
Daud_1580Formate dehydrogenase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sth:STH2601 formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (808 aa)
Daud_1581Formate dehydrogenase; PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sth:STH2602 putative formate dehydrogenase subunit. (216 aa)
Daud_1651PFAM: nickel-dependent hydrogenase, large subunit; KEGG: ade:Adeh_4162 nickel-dependent hydrogenase, large subunit. (485 aa)
Daud_1652PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: ade:Adeh_4163 methyl-viologen-reducing hydrogenase, delta subunit. (317 aa)
Daud_1653PFAM: methyl-viologen-reducing hydrogenase, delta subunit; KEGG: mth:MTH1138 methyl viologen-reducing hydrogenase, delta subunit homolog FlpD. (146 aa)
fbpProtein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (370 aa)
Daud_1881CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: mta:Moth_0810 protein of unknown function DUF224, cysteine-rich region. (295 aa)
Daud_1941KEGG: chy:CHY_1544 [Ni/Fe] hydrogenase, b-type cytochrome subunit. (186 aa)
Daud_1946Pyruvate, water dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; KEGG: sru:SRU_1138 phosphoenolpyruvate synthase. (1115 aa)
Daud_1961PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: aae:aq_1168 pyruvate ferredoxin oxidoreductase, beta subunit. (286 aa)
Daud_1962PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: aae:aq_1167 pyruvate ferredoxin oxidoreductase, alpha subunit. (394 aa)
Daud_1963PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: afu:AF1700 pyruvate ferredoxin oxidoreductase, delta subunit. (64 aa)
Daud_1964TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: aae:aq_1169 pyruvate ferredoxin oxidoreductase, gamma subunit. (223 aa)
Daud_1965PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: aae:aq_1168 pyruvate ferredoxin oxidoreductase, beta subunit. (290 aa)
Daud_1966PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: aae:aq_1167 pyruvate ferredoxin oxidoreductase, alpha subunit. (380 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
Daud_2175KEGG: chy:CHY_0128 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase, class-II. (288 aa)
Your Current Organism:
Desulforudis audaxviator
NCBI taxonomy Id: 477974
Other names: C. Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator str. MP104C, Candidatus Desulforudis audaxviator strain MP104C
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