STRINGSTRING
fhs fhs folD folD Daud_0104 Daud_0104 Daud_0112 Daud_0112 Daud_0113 Daud_0113 Daud_0114 Daud_0114 Daud_0117 Daud_0117 fhs-2 fhs-2 ppcA ppcA Daud_0870 Daud_0870 Daud_0871 Daud_0871 Daud_0872 Daud_0872 Daud_0875 Daud_0875 Daud_0876 Daud_0876 Daud_0880 Daud_0880 Daud_1016 Daud_1016 folD-2 folD-2 accD accD accA accA mdh mdh Daud_1249 Daud_1249 Daud_1253 Daud_1253 Daud_1254 Daud_1254 acsA acsA Daud_1606 Daud_1606 Daud_1607 Daud_1607 Daud_1608 Daud_1608 Daud_1609 Daud_1609 Daud_1926 Daud_1926 Daud_1927 Daud_1927 Daud_1928 Daud_1928 Daud_1929 Daud_1929 Daud_1930 Daud_1930 Daud_1931 Daud_1931 Daud_1946 Daud_1946 Daud_1961 Daud_1961 Daud_1962 Daud_1962 Daud_1963 Daud_1963 Daud_1964 Daud_1964 Daud_1965 Daud_1965 Daud_1966 Daud_1966 Daud_2072 Daud_2072 Daud_2073 Daud_2073 Daud_2075 Daud_2075
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fhsPFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: rxy:Rxyl_2519 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (566 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
Daud_0104TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: chy:CHY_0733 NAD-dependent formate dehydrogenase, alpha subunit, selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (724 aa)
Daud_0112PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; Fe-S cluster domain protein; KEGG: det:DET0699 corrinoid/iron-sulfur protein, large subunit. (452 aa)
Daud_0113PFAM: dihydropteroate synthase, DHPS; KEGG: chy:CHY_1227 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase. (290 aa)
Daud_0114KEGG: det:DET0701 corrinoid/iron-sulfur protein, small subunit. (298 aa)
Daud_0117PFAM: methylenetetrahydrofolate reductase; KEGG: mta:Moth_1191 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (306 aa)
fhs-2PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: chy:CHY_2385 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (557 aa)
ppcAProtein of unknown function DUF557; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (489 aa)
Daud_0870KEGG: mma:MM0121 carbon monoxide dehydrogenase; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane. (628 aa)
Daud_0871KEGG: det:DET0700 carbon monoxide dehydrogenase, alpha subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit. (735 aa)
Daud_0872PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; Fe-S cluster domain protein; KEGG: chy:CHY_1223 acetyl-CoA decarbonylase/synthase complex subunit gamma. (443 aa)
Daud_0875PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; KEGG: chy:CHY_1226 acetyl-CoA decarbonylase/synthase complex subunit delta. (326 aa)
Daud_0876PFAM: dihydropteroate synthase, DHPS; KEGG: chy:CHY_1227 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase. (281 aa)
Daud_0880PFAM: methylenetetrahydrofolate reductase; KEGG: mta:Moth_1191 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (314 aa)
Daud_1016acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
folD-2Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (275 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)
Daud_1249L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: gme:Gmet_2911 fumarate reductase/succinate dehydrogenase flavoprotein-like. (532 aa)
Daud_1253TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: mta:Moth_2282 hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region. (186 aa)
Daud_1254TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; KEGG: chy:CHY_1375 fumarate hydratase. (294 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
Daud_1606PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: dde:Dde_0046 pyruvate ferredoxin/flavodoxin oxidoreductase family protein. (192 aa)
Daud_1607PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: swo:Swol_1399 putative keto/oxoacid ferredoxin oxidoreductase, beta subunit. (221 aa)
Daud_1608PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: chy:CHY_1972 2-oxoglutarate ferredoxin oxidoreductase. (367 aa)
Daud_1609PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: swo:Swol_1401 4Fe-4S ferredoxin, iron-sulfur binding. (80 aa)
Daud_1926KEGG: chy:CHY_0443 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family. (890 aa)
Daud_1927TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; KEGG: mta:Moth_2283 hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region. (280 aa)
Daud_1928TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: aae:aq_1679 fumarate hydratase beta subunit. (187 aa)
Daud_1929KEGG: dde:Dde_1258 fumarate reductase, cytochrome b subunit. (212 aa)
Daud_1930KEGG: dvu:DVU3262 fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (595 aa)
Daud_1931TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: dvu:DVU3263 fumarate reductase, iron-sulfur protein. (247 aa)
Daud_1946Pyruvate, water dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; KEGG: sru:SRU_1138 phosphoenolpyruvate synthase. (1115 aa)
Daud_1961PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: aae:aq_1168 pyruvate ferredoxin oxidoreductase, beta subunit. (286 aa)
Daud_1962PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: aae:aq_1167 pyruvate ferredoxin oxidoreductase, alpha subunit. (394 aa)
Daud_1963PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: afu:AF1700 pyruvate ferredoxin oxidoreductase, delta subunit. (64 aa)
Daud_1964TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: aae:aq_1169 pyruvate ferredoxin oxidoreductase, gamma subunit. (223 aa)
Daud_1965PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: aae:aq_1168 pyruvate ferredoxin oxidoreductase, beta subunit. (290 aa)
Daud_1966PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: aae:aq_1167 pyruvate ferredoxin oxidoreductase, alpha subunit. (380 aa)
Daud_2072PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: chy:CHY_0046 putative keto/oxoacid ferredoxin oxidoreductase, delta subunit. (92 aa)
Daud_2073TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: chy:CHY_0045 putative keto/oxoacid ferredoxin oxidoreductase, gamma subunit. (195 aa)
Daud_2075PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: chy:CHY_0043 putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit. (380 aa)
Your Current Organism:
Desulforudis audaxviator
NCBI taxonomy Id: 477974
Other names: C. Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator MP104C, Candidatus Desulforudis audaxviator str. MP104C, Candidatus Desulforudis audaxviator strain MP104C
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