STRINGSTRING
OBX83306.1 OBX83306.1 recB recB recD recD OBX83359.1 OBX83359.1 OBX83392.1 OBX83392.1 OBX83396.1 OBX83396.1 OBX83604.1 OBX83604.1 OBX83460.1 OBX83460.1 recR recR OBX82980.1 OBX82980.1 OBX82986.1 OBX82986.1 OBX82501.1 OBX82501.1 OBX85506.1 OBX85506.1 OBX88357.1 OBX88357.1 OBX88395.1 OBX88395.1 polA polA recA recA ruvC ruvC OBX85116.1 OBX85116.1 OBX87234.1 OBX87234.1 OBX87292.1 OBX87292.1 ruvB ruvB recG recG rnt rnt OBX87126.1 OBX87126.1 OBX84976.1 OBX84976.1 OBX85024.1 OBX85024.1 priA priA OBX85066.1 OBX85066.1 recF recF OBX84054.1 OBX84054.1 OBX83155.1 OBX83155.1 OBX83219.1 OBX83219.1 dnaX dnaX ruvA ruvA OBX83305.1 OBX83305.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OBX83306.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1400 aa)
recBHypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...] (1291 aa)
recDExodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (708 aa)
OBX83359.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (223 aa)
OBX83392.1Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (503 aa)
OBX83396.1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)
OBX83604.1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
OBX83460.1Helicase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (628 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa)
OBX82980.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (466 aa)
OBX82986.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (298 aa)
OBX82501.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
OBX85506.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
OBX88357.1Hypothetical protein; Involved in DNA repair and RecF pathway recombination. (250 aa)
OBX88395.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (386 aa)
polAHypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (964 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (352 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (195 aa)
OBX85116.1single-stranded-DNA-specific exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
OBX87234.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
OBX87292.1Filamentation induced by cAMP protein fic; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (327 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (700 aa)
rntRibonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (219 aa)
OBX87126.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
OBX84976.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
OBX85024.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (329 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (767 aa)
OBX85066.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
recFHypothetical protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (381 aa)
OBX84054.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (379 aa)
OBX83155.1Addiction module protein; Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. (362 aa)
OBX83219.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (161 aa)
dnaXDNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (643 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (208 aa)
OBX83305.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1263 aa)
Your Current Organism:
Moraxella nonliquefaciens
NCBI taxonomy Id: 478
Other names: ATCC 19975, Bacillus duplex non liquefaciens, CCUG 348, CIP 68.36, DSM 6327, JCM 20443, M. nonliquefaciens, NCTC 10464, strain 4663/62
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