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A0A0N7L3R5 A0A0N7L3R5 A0A0N7L636 A0A0N7L636 A0A0N7L6B7 A0A0N7L6B7 A0A0N7L782 A0A0N7L782 A0A0P1A3Q1 A0A0P1A3Q1 A0A0P1A5G6 A0A0P1A5G6 A0A0P1A6Y8 A0A0P1A6Y8 A0A0P1A7Q0 A0A0P1A7Q0 MCM7 MCM7 FEN1 FEN1 A0A0P1ABM7 A0A0P1ABM7 A0A0P1ABV5 A0A0P1ABV5 A0A0P1ACK9 A0A0P1ACK9 A0A0P1ACV5 A0A0P1ACV5 A0A0P1AFV1 A0A0P1AFV1 A0A0P1AHE0 A0A0P1AHE0 A0A0P1AKT0 A0A0P1AKT0 A0A0P1AL31 A0A0P1AL31 A0A0P1ALZ8 A0A0P1ALZ8 A0A0P1AMN8 A0A0P1AMN8 A0A0P1AQX3 A0A0P1AQX3 A0A0P1AUM6 A0A0P1AUM6 A0A0P1AV88 A0A0P1AV88 A0A0P1AW42 A0A0P1AW42 A0A0P1AX87 A0A0P1AX87 A0A0P1B113 A0A0P1B113 A0A0P1B2C1 A0A0P1B2C1 A0A0P1B2I4 A0A0P1B2I4 A0A0P1B304 A0A0P1B304 A0A0P1B376 A0A0P1B376 A0A0P1B5L2 A0A0P1B5L2 A0A0P1B5Z1 A0A0P1B5Z1 A0A0P1B6Q1 A0A0P1B6Q1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A0N7L3R5DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (468 aa)
A0A0N7L636Dna primase large subunit-like. (427 aa)
A0A0N7L6B7Dna replication licensing factor mcm8; Belongs to the MCM family. (761 aa)
A0A0N7L782Origin recognition complex, subunit 3. (975 aa)
A0A0P1A3Q1DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (625 aa)
A0A0P1A5G6DNA primase; Belongs to the eukaryotic-type primase small subunit family. (403 aa)
A0A0P1A6Y8Atpase family aaa domain-containing protein 5. (1042 aa)
A0A0P1A7Q0Dna polymerase epsilon subunit 3-like. (146 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (805 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (426 aa)
A0A0P1ABM7Dna replication licensing factor; Belongs to the MCM family. (433 aa)
A0A0P1ABV5Origin recognition complex. (398 aa)
A0A0P1ACK9Cell division control protein 45. (489 aa)
A0A0P1ACV5Atorc6 orc6. (312 aa)
A0A0P1AFV1DNA polymerase. (1089 aa)
A0A0P1AHE0DNA helicase; Belongs to the MCM family. (2765 aa)
A0A0P1AKT0DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (533 aa)
A0A0P1AL31DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2380 aa)
A0A0P1ALZ8Mcm10-like protein. (420 aa)
A0A0P1AMN8DNA helicase; Belongs to the MCM family. (740 aa)
A0A0P1AQX3DNA helicase; Belongs to the MCM family. (1008 aa)
A0A0P1AUM6Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (526 aa)
A0A0P1AV88DNA polymerase. (1574 aa)
A0A0P1AW42Cell division control protein cdc6. (554 aa)
A0A0P1AX87Dna replication licensing factor. (648 aa)
A0A0P1B113DNA helicase; Belongs to the MCM family. (887 aa)
A0A0P1B2C1Uncharacterized protein. (490 aa)
A0A0P1B2I4Dna replication licensing factor mcm9; Belongs to the MCM family. (791 aa)
A0A0P1B304Cell division control protein 6 homolog. (1209 aa)
A0A0P1B376DNA replication factor. (347 aa)
A0A0P1B5L2Origin recognition complex, subunit 4. (708 aa)
A0A0P1B5Z1Dna polymerase alpha epsilon subunit. (472 aa)
A0A0P1B6Q1Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
Your Current Organism:
Plasmopara halstedii
NCBI taxonomy Id: 4781
Other names: P. halstedii, Peronospora halstedii
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