(25 nodes) Terpenoid backbone biosynthesis network (Plasmopara halstedii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	A0A0P1ANM0	Mevalonate kinase. (389 aa)
	A0A0P1AQD0	Farnesyl pyrophosphate synthetase. (224 aa)
	A0A0P1AQL0	Galactose-binding domain-like. (911 aa)
	A0A0P1AT52	Alkyl transferase; Belongs to the UPP synthase family. (351 aa)
	A0A0P1AUD3	Solute carrier family 35 member f2. (316 aa)
	A0A0P1AUT0	Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (296 aa)
	A0A0P1AXF3	Isopentenyl-diphosphate delta-isomerase. (237 aa)
	A0A0P1B000	Protein farnesyltransferase. (478 aa)
	A0A0P1B1U6	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (830 aa)
	A0A0P1B7W1	Acetyl-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
	A0A0P1B7G8	Uncharacterized conserved protein. (396 aa)
	A0A0P1B5S2	Uncharacterized protein. (699 aa)
	A0A0P1B476	Hydroxymethylglutaryl-degradative. (969 aa)
	A0A0P1B321	Caax prenyl protease 2. (316 aa)
	A0A0N7L712	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (419 aa)
	A0A0N7L852	Probable isoprenylcysteine alpha-carbonyl methylesterase icmel2. (554 aa)
	A0A0P1A9J1	Phosphomevalonate kinase. (384 aa)
	A0A0P1AA81	Drug metabolite transporter superfamily. (331 aa)
	A0A0P1AB75	Alkyl transferase; Belongs to the UPP synthase family. (259 aa)
	A0A0P1ABC5	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (458 aa)
	A0A0P1AC12	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (404 aa)
	A0A0P1AC31	Hydroxymethylglutaryl-synthase. (951 aa)
	A0A0P1AGZ3	Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (422 aa)
	A0A0P1AIM4	NAD(P)-binding domain. (804 aa)
	A0A0P1ALY9	Protein-S-isoprenylcysteine O-methyltransferase. (188 aa)

Your Current Organism:

Plasmopara halstedii

NCBI taxonomy Id: 4781
Other names: P. halstedii, Peronospora halstedii

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0N7L712	A0A0P1AB75	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Alkyl transferase; Belongs to the UPP synthase family.	0.686
A0A0N7L712	A0A0P1ABC5	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.936
A0A0N7L712	A0A0P1AGZ3	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.	0.890
A0A0N7L712	A0A0P1AIM4	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	NAD(P)-binding domain.	0.816
A0A0N7L712	A0A0P1ALY9	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Protein-S-isoprenylcysteine O-methyltransferase.	0.416
A0A0N7L712	A0A0P1AQD0	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Farnesyl pyrophosphate synthetase.	0.944
A0A0N7L712	A0A0P1AT52	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Alkyl transferase; Belongs to the UPP synthase family.	0.686
A0A0N7L712	A0A0P1AUT0	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.939
A0A0N7L712	A0A0P1AXF3	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Isopentenyl-diphosphate delta-isomerase.	0.419
A0A0N7L712	A0A0P1B000	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Protein farnesyltransferase.	0.998
A0A0N7L712	A0A0P1B321	Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.	Caax prenyl protease 2.	0.945
A0A0N7L852	A0A0P1ALY9	Probable isoprenylcysteine alpha-carbonyl methylesterase icmel2.	Protein-S-isoprenylcysteine O-methyltransferase.	0.890
A0A0N7L852	A0A0P1B321	Probable isoprenylcysteine alpha-carbonyl methylesterase icmel2.	Caax prenyl protease 2.	0.895
A0A0P1A9J1	A0A0P1AC12	Phosphomevalonate kinase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.947
A0A0P1A9J1	A0A0P1AC31	Phosphomevalonate kinase.	Hydroxymethylglutaryl-synthase.	0.447
A0A0P1A9J1	A0A0P1ANM0	Phosphomevalonate kinase.	Mevalonate kinase.	0.922
A0A0P1A9J1	A0A0P1AQD0	Phosphomevalonate kinase.	Farnesyl pyrophosphate synthetase.	0.416
A0A0P1A9J1	A0A0P1AQL0	Phosphomevalonate kinase.	Galactose-binding domain-like.	0.542
A0A0P1A9J1	A0A0P1AUT0	Phosphomevalonate kinase.	Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.	0.405
A0A0P1A9J1	A0A0P1AXF3	Phosphomevalonate kinase.	Isopentenyl-diphosphate delta-isomerase.	0.439