node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sros_2137 | Sros_2587 | Sros_2137 | Sros_2587 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; KEGG: cko:CKO_04984 hypothetical protein. | 0.750 |
Sros_2137 | Sros_2740 | Sros_2137 | Sros_2740 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: bsu:BSU02410 homocysteine methyltransferase. | 0.944 |
Sros_2137 | Sros_2788 | Sros_2137 | Sros_2788 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: afw:Anae109_2667 5,10- methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.995 |
Sros_2137 | Sros_3143 | Sros_2137 | Sros_3143 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminotransferase; KEGG: bsu:BSU31440 aminotransferase. | 0.918 |
Sros_2137 | Sros_3752 | Sros_2137 | Sros_3752 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: bbt:BBta_0633 putative cysteine synthase (O- acetylserine sulfhydrylase) (O-acetylserine (thiol)-lyase) (CSase). | 0.927 |
Sros_2137 | Sros_5917 | Sros_2137 | Sros_5917 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.988 |
Sros_2137 | Sros_8009 | Sros_2137 | Sros_8009 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: sfu:Sfum_2670 cystathionine gamma-synthase. | 0.750 |
Sros_2137 | Sros_8078 | Sros_2137 | Sros_8078 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: mxa:MXAN_1973 hypothetical protein. | 0.709 |
Sros_2137 | Sros_8563 | Sros_2137 | Sros_8563 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | 0.973 |
Sros_2137 | Sros_8566 | Sros_2137 | Sros_8566 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: scl:sce0438 cystathionine beta-synthase. | 0.941 |
Sros_2137 | Sros_8776 | Sros_2137 | Sros_8776 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | MetE; KEGG: dat:HRM2_34760 MetE. | 0.970 |
Sros_2137 | Sros_8789 | Sros_2137 | Sros_8789 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: sfu:Sfum_0366 adenosylhomocysteinase. | 0.942 |
Sros_2137 | Sros_8985 | Sros_2137 | Sros_8985 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5 10-methylenetetrahydrofolate reductase-like protein; KEGG: gur:Gura_1171 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.993 |
Sros_2137 | ahcY | Sros_2137 | Sros_1392 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.942 |
Sros_2137 | ahcY-2 | Sros_2137 | Sros_1393 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.942 |
Sros_2137 | metE | Sros_2137 | Sros_7219 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate--homocyste ineS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.970 |
Sros_2137 | metK | Sros_2137 | Sros_2818 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.965 |
Sros_2587 | Sros_2137 | Sros_2587 | Sros_2137 | Cystathionine gamma-synthase; KEGG: cko:CKO_04984 hypothetical protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.750 |
Sros_2587 | Sros_2788 | Sros_2587 | Sros_2788 | Cystathionine gamma-synthase; KEGG: cko:CKO_04984 hypothetical protein. | KEGG: afw:Anae109_2667 5,10- methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.722 |
Sros_2587 | Sros_3143 | Sros_2587 | Sros_3143 | Cystathionine gamma-synthase; KEGG: cko:CKO_04984 hypothetical protein. | Aminotransferase; KEGG: bsu:BSU31440 aminotransferase. | 0.549 |