STRINGSTRING
Sros_0110 Sros_0110 pheA pheA pat pat Sros_0542 Sros_0542 Sros_0868 Sros_0868 Sros_1066 Sros_1066 trpD trpD Sros_2759 Sros_2759 Sros_2890 Sros_2890 Sros_2906 Sros_2906 hisD hisD hisC hisC hisB hisB Sros_2910 Sros_2910 hisH hisH Sros_2912 Sros_2912 hisA hisA Sros_2914 Sros_2914 hisF hisF hisI hisI trpC trpC trpB trpB trpA trpA Sros_2997 Sros_2997 Sros_2998 Sros_2998 Sros_3288 Sros_3288 trpF trpF Sros_3761 Sros_3761 Sros_3775 Sros_3775 aroK aroK Sros_3982 Sros_3982 trpB-2 trpB-2 trpA-2 trpA-2 Sros_5214 Sros_5214 aroQ aroQ hisG hisG hisE hisE Sros_6090 Sros_6090 Sros_6149 Sros_6149 aroQ-2 aroQ-2 aroB aroB aroK-2 aroK-2 aroC aroC Sros_6775 Sros_6775 Sros_6984 Sros_6984 Sros_6985 Sros_6985 trpD-2 trpD-2 aroA aroA Sros_8330 Sros_8330 Sros_9291 Sros_9291 Sros_9365 Sros_9365
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Sros_0110KEGG: gbe:GbCGDNIH1_0821 anthranilate synthase component II. (190 aa)
pheAKEGG: ade:Adeh_1779 prephenate dehydratase. (306 aa)
patHistidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (353 aa)
Sros_0542Phosphoserine phosphatase-like protein; KEGG: afw:Anae109_1214 HAD family hydrolase. (289 aa)
Sros_0868KEGG: afw:Anae109_3449 inositol-phosphate phosphatase. (267 aa)
Sros_1066KEGG: ppd:Ppro_2189 aminotransferase, class I and II. (401 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa)
Sros_27593-deoxy-7-phosphoheptulonate synthase; KEGG: afw:Anae109_0367 phospho-2-dehydro-3- deoxyheptonate aldolase. (345 aa)
Sros_28903-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase-like protein; KEGG: mxa:MXAN_3526 phospho-2-dehydro-3- deoxyheptonate aldolase. (264 aa)
Sros_2906KEGG: dvm:DvMF_2065 YbaK/EbsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (166 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
hisCKEGG: bur:Bcep18194_C7445 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa)
hisBKEGG: dal:Dalk_3080 imidazoleglycerol-phosphate dehydratase. (206 aa)
Sros_2910Hypothetical protein. (51 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (209 aa)
Sros_2912Hypothetical protein. (113 aa)
hisAPhosphoribosylanthranilate isomerase; KEGG: plu:plu0797 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase. (240 aa)
Sros_2914KEGG: mxa:MXAN_5993 hypothetical protein. (135 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (115 aa)
trpCKEGG: afw:Anae109_0373 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (269 aa)
trpBTryptophan synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa)
Sros_2997KEGG: ade:Adeh_0182 chorismate mutase. (119 aa)
Sros_2998Prephenate dehydrogenase-like protein; KEGG: bpt:Bpet1887 hypothetical protein. (357 aa)
Sros_3288KEGG: rce:RC1_0952 3-deoxy-7-phosphoheptulonate synthase; Belongs to the class-II DAHP synthase family. (443 aa)
trpFKEGG: sil:SPO0806 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (211 aa)
Sros_3761KEGG: oca:OCAR_5217 para-aminobenzoate synthase. (703 aa)
Sros_37753-deoxy-7-phosphoheptulonate synthase; KEGG: ppf:Pput_3849 phospho-2-dehydro-3- deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (388 aa)
aroK3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (175 aa)
Sros_3982KEGG: scl:sce5044 anthranilate synthase. (715 aa)
trpB-2Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
trpA-2Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa)
Sros_5214KEGG: afw:Anae109_2478 inositol monophosphatase. (267 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (153 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa)
hisEPhosphoribosyl-ATP pyrophosphohydrolase-like protein; KEGG: smt:Smal_1763 phosphoribosyl-ATP diphosphatase. (87 aa)
Sros_6090KEGG: bam:Bamb_5913 shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (274 aa)
Sros_6149Anthranilate synthase; KEGG: met:M446_0053 para-aminobenzoate synthase, subunit I. (340 aa)
aroQ-23-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (358 aa)
aroK-2Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (167 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (392 aa)
Sros_6775KEGG: csa:Csal_1824 inositol-1(or 4)- monophosphatase. (264 aa)
Sros_6984KEGG: bpt:Bpet1887 hypothetical protein. (283 aa)
Sros_69853-deoxy-7-phosphoheptulonate synthase; KEGG: glo:Glov_2802 phospho-2-dehydro-3- deoxyheptonate aldolase. (346 aa)
trpD-2Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (352 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (425 aa)
Sros_8330KEGG: ade:Adeh_1287 histidinol-phosphate phosphatase. (267 aa)
Sros_9291Aminotransferase; KEGG: csa:Csal_1034 aminotransferase. (426 aa)
Sros_9365KEGG: sme:SM_b20249 putative myo-inositol-1- phosphate synthase. (359 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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