STRINGSTRING
acsA acsA Sros_1890 Sros_1890 Sros_1947 Sros_1947 Sros_1948 Sros_1948 Sros_6151 Sros_6151 Sros_6712 Sros_6712 ackA ackA Sros_7969 Sros_7969 ackA-2 ackA-2 Sros_7971 Sros_7971
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)
Sros_1890KEGG: rce:RC1_1843 propionate--CoA ligase. (695 aa)
Sros_1947Aminotransferase; KEGG: sus:Acid_7662 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
Sros_1948KEGG: sus:Acid_0680 methylmalonate-semialdehyde dehydrogenase [acylating]. (501 aa)
Sros_61513-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase-like protein; KEGG: ppd:Ppro_2197 2-hydroxy-3-oxopropionate reductase. (402 aa)
Sros_6712KEGG: swi:Swit_2088 aldehyde dehydrogenase (acceptor). (479 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (381 aa)
Sros_7969KEGG: bur:Bcep18194_B1170 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (378 aa)
Sros_7971Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (681 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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