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hemA hemA hemC hemC Sros_0550 Sros_0550 Sros_0551 Sros_0551 hemL hemL Sros_3086 Sros_3086 Sros_5894 Sros_5894 Sros_6718 Sros_6718 Sros_6719 Sros_6719 hemE hemE hemH hemH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (440 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (306 aa)
Sros_0550KEGG: gme:Gmet_3235 uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase. (526 aa)
Sros_0551Porphobilinogen synthase; KEGG: sfu:Sfum_3057 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (328 aa)
hemLKEGG: aeh:Mlg_0806 glutamate-1-semialdehyde 2,1- aminomutase. (437 aa)
Sros_3086Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pca:Pcar_0266 glutamate-1-semialdehyde-2,1- aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)
Sros_5894Aminotransferase; KEGG: nar:Saro_0248 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (407 aa)
Sros_6718Conserved hypothetical protein; KEGG: bsu:BSU37670 putative heme peroxidase. (235 aa)
Sros_6719KEGG: bsu:BSU10140 protoporphyrinogen oxidase. (479 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (345 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (332 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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