STRINGSTRING
Sros_0003 Sros_0003 Sros_1999 Sros_1999 Sros_2183 Sros_2183 Sros_2187 Sros_2187 Sros_2188 Sros_2188 kmo kmo Sros_2190 Sros_2190 Sros_3051 Sros_3051 Sros_4715 Sros_4715 Sros_4716 Sros_4716 Sros_4717 Sros_4717 Sros_4718 Sros_4718 Sros_4761 Sros_4761 Sros_4762 Sros_4762 Sros_5324 Sros_5324 Sros_5666 Sros_5666 Sros_5667 Sros_5667 kynA kynA kynA-2 kynA-2 Sros_7490 Sros_7490 Sros_7491 Sros_7491 Sros_7496 Sros_7496 Sros_7498 Sros_7498 Sros_7499 Sros_7499 Sros_7500 Sros_7500 Sros_7501 Sros_7501 Sros_7502 Sros_7502 Sros_7503 Sros_7503 Sros_7504 Sros_7504 Sros_7520 Sros_7520 Sros_7522 Sros_7522 dapA-3 dapA-3 Sros_7524 Sros_7524 Sros_7525 Sros_7525 Sros_7818 Sros_7818 Sros_7819 Sros_7819 Sros_9106 Sros_9106 kynU kynU Sros_9108 Sros_9108 Sros_9109 Sros_9109 nbaC nbaC Sros_9111 Sros_9111 Sros_9112 Sros_9112 Sros_9113 Sros_9113 Sros_9114 Sros_9114 Sros_9115 Sros_9115 Sros_9116 Sros_9116 Sros_9117 Sros_9117
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_0003KEGG: mlo:mll1845 hypothetical protein. (243 aa)
Sros_1999KEGG: swi:Swit_2102 cyclase family protein. (307 aa)
Sros_2183Beta-N-acetylhexosaminidase; KEGG: ade:Adeh_4264 glycoside hydrolase family protein. (504 aa)
Sros_2187KEGG: mxa:MXAN_4404 major facilitator family transporter. (495 aa)
Sros_2188Hypothetical protein; KEGG: dar:Daro_1530 O-methyltransferase family protein. (411 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (440 aa)
Sros_2190KEGG: rec:RHECIAT_PB0000363 hypothetical protein. (226 aa)
Sros_3051KEGG: plu:plu1439 hypothetical protein. (257 aa)
Sros_4715Hypothetical protein; KEGG: bbr:BB4131 putative dioxygenase. (292 aa)
Sros_4716KEGG: csa:Csal_0325 extradiol ring-cleavage dioxygenase LigAB, LigA subunit. (109 aa)
Sros_4717Aminocarboxymuconate-semialdehyde decarboxylase; KEGG: swi:Swit_1683 amidohydrolase 2. (358 aa)
Sros_4718KEGG: hypothetical protein. (203 aa)
Sros_4761Hypothetical protein. (111 aa)
Sros_4762AraC-type DNA-binding domain-containing protein- like protein; KEGG: mrd:Mrad2831_4851 AraC family transcriptional regulator. (353 aa)
Sros_5324KEGG: rle:pRL80036 hypothetical protein. (318 aa)
Sros_5666Putative transcriptional regulator, XRE family; KEGG: bra:BRADO4150 hypothetical protein. (273 aa)
Sros_5667KEGG: met:M446_5919 putative esterase. (241 aa)
kynATryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (294 aa)
kynA-2Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (264 aa)
Sros_7490KEGG: bsu:BSU38450 hypothetical protein. (190 aa)
Sros_7491KEGG: mxa:MXAN_4126 ferredoxin reductase. (62 aa)
Sros_7496KEGG: sil:SPO0764 cytochrome P450 family protein. (415 aa)
Sros_7498KEGG: nar:Saro_2597 acetoacetate decarboxylase. (269 aa)
Sros_7499KEGG: rlt:Rleg2_4433 amino acid permease-associated region. (495 aa)
Sros_7500KEGG: bsu:BSU38450 hypothetical protein. (190 aa)
Sros_7501KEGG: afr:AFE_2528 glutamine amidotransferase, class I. (230 aa)
Sros_7502KEGG: pla:Plav_1786 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (482 aa)
Sros_7503KEGG: bpm:BURPS1710b_A1686 putative dioxygenase. (307 aa)
Sros_7504KEGG: nar:Saro_2598 5-carboxymethyl-2- hydroxymuconate delta-isomerase. (281 aa)
Sros_7520KEGG: rpa:RPA1663 putative 3,4- dihydroxyphenylacetate 2,3-dioxygenase. (285 aa)
Sros_75225-carboxymethyl-2-hydroxymuconateDelta- isomerase; KEGG: bpy:Bphyt_4892 dimethylmenaquinone methyltransferase. (545 aa)
dapA-3Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (304 aa)
Sros_7524Betaine-aldehyde dehydrogenase; KEGG: ppg:PputGB1_3498 5-carboxymethyl-2- hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (488 aa)
Sros_7525KEGG: noc:Noc_2954 hypothetical protein. (130 aa)
Sros_7818KEGG: swi:Swit_0986 AraC family transcriptional regulator. (342 aa)
Sros_7819Hypothetical protein. (161 aa)
Sros_9106KEGG: bpy:Bphyt_1477 hypothetical protein. (594 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (407 aa)
Sros_9108ABC-type branched-chain amino acid transport systems ATPase component-like protein; KEGG: rle:pRL90261 putative ATP-binding ABC transporter. (254 aa)
Sros_9109KEGG: aba:Acid345_0682 tryptophan 2,3-dioxygenase. (323 aa)
nbaC3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (171 aa)
Sros_9111KEGG: bpy:Bphyt_1470 endoribonuclease L-PSP. (140 aa)
Sros_9112KEGG: ara:Arad_7266 4-oxalocrotonate decarboxylase. (255 aa)
Sros_91134-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (337 aa)
Sros_9114Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (325 aa)
Sros_9115KEGG: rso:RS01662 putative hydratase protein. (265 aa)
Sros_9116KEGG: swi:Swit_3519 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (484 aa)
Sros_9117KEGG: eba:ebA4048 IclR family transciptional regulator. (252 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
Server load: low (20%) [HD]