STRINGSTRING
ispD ispD Sros_0598 Sros_0598 ispF ispF dxr dxr ispG ispG Sros_2336 Sros_2336 Sros_2736 Sros_2736 Sros_2787 Sros_2787 ispG-2 ispG-2 dxs dxs ispH ispH Sros_3714 Sros_3714 Sros_3716 Sros_3716 Sros_3827 Sros_3827 Sros_3828 Sros_3828 Sros_3830 Sros_3830 Sros_4146 Sros_4146 Sros_4472 Sros_4472 Sros_5159 Sros_5159 dxs-2 dxs-2 Sros_6866 Sros_6866 Sros_6906 Sros_6906 Sros_8223 Sros_8223 ispH-2 ispH-2 Sros_8524 Sros_8524 ispE ispE idi idi
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ispDPyrophosphorylase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the short-chain dehydrogenases/reductases (SDR) family. (470 aa)
Sros_0598Trans-hexaprenyltranstransferase; KEGG: pde:Pden_2031 trans- hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family. (331 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (394 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (388 aa)
Sros_2336Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa)
Sros_2736Hypothetical protein; KEGG: ppw:PputW619_4600 NUDIX hydrolase. (196 aa)
Sros_2787KEGG: mxa:MXAN_0894 putative farnesyltranstransferase; Belongs to the FPP/GGPP synthase family. (355 aa)
ispG-24-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (402 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (647 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (339 aa)
Sros_3714Geranylgeranyl pyrophosphate synthase-like protein; KEGG: sfu:Sfum_1417 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (350 aa)
Sros_37164-hydroxy-3-methylbut-2-enyl diphosphate reductase; KEGG: lhk:LHK_00616 IspH. (420 aa)
Sros_3827KEGG: mxa:MXAN_0895 phytoene desaturase. (489 aa)
Sros_3828Phytoene synthase; KEGG: sus:Acid_1266 farnesyl-diphosphate farnesyltransferase. (299 aa)
Sros_3830KEGG: rde:RD1_0121 spheroidene monooxygenase. (225 aa)
Sros_4146All-trans-retinol 13,14-reductase; KEGG: scl:sce3350 putative phytoene dehydrogenase. (562 aa)
Sros_4472Secreted hydrolase-like protein; KEGG: avi:Avi_0323 hypothetical protein. (360 aa)
Sros_5159KEGG: dvu:DVU3179 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (322 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa)
Sros_6866Hypothetical protein; Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to yield the bicyclic sesquiterpenol 4-epi-cubebol via a 1,10- cyclization, which requires the abstraction of the pyrophosphate from FPP to yield a (E,E)-germacradienyl cation. The only accepted substrate is (2E,6E)-farnesyl diphosphate (FPP). (330 aa)
Sros_6906Geranylgeranyl pyrophosphate synthase-like protein; KEGG: sfu:Sfum_1417 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (346 aa)
Sros_8223Trans-hexaprenyltranstransferase; KEGG: reh:H16_A3253 trans- hexaprenyltranstransferase; Belongs to the FPP/GGPP synthase family. (326 aa)
ispH-24-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (322 aa)
Sros_8524Z-farnesyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (255 aa)
ispE4-diphosphocytidyl-2-C-methyl-D- erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (300 aa)
idiIsopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (193 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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