STRINGSTRING
Sros_5957 Sros_5957 dapD dapD Sros_6183 Sros_6183 Sros_6500 Sros_6500 Sros_6725 Sros_6725 Sros_6748 Sros_6748 Sros_6820 Sros_6820 Sros_7214 Sros_7214 metE metE Sros_7402 Sros_7402 Sros_7561 Sros_7561 Sros_7680 Sros_7680 Sros_7849 Sros_7849 Sros_8078 Sros_8078 Sros_8265 Sros_8265 Sros_8366 Sros_8366 Sros_8429 Sros_8429 Sros_8431 Sros_8431 Sros_8654 Sros_8654 Sros_9311 Sros_9311 Sros_8776 Sros_8776 Sros_9310 Sros_9310 Sros_8913 Sros_8913 Sros_0061 Sros_0061 Sros_0327 Sros_0327 folD folD Sros_0440 Sros_0440 folD-2 folD-2 Sros_1268 Sros_1268 Sros_1518 Sros_1518 Sros_1634 Sros_1634 lysA lysA Sros_1638 Sros_1638 Sros_1649 Sros_1649 thrB thrB Sros_1779 Sros_1779 Sros_2030 Sros_2030 dapB dapB Sros_2137 Sros_2137 dapF dapF Sros_2361 Sros_2361 Sros_2367 Sros_2367 Sros_2502 Sros_2502 Sros_2740 Sros_2740 Sros_2788 Sros_2788 Sros_3531 Sros_3531 Sros_3753 Sros_3753 Sros_4169 Sros_4169 Sros_4248 Sros_4248 Sros_4372 Sros_4372 Sros_4607 Sros_4607 Sros_5213 Sros_5213 Sros_5254 Sros_5254 Sros_5539 Sros_5539 lysA-2 lysA-2 Sros_5703 Sros_5703 Sros_5917 Sros_5917
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_5957KEGG: kpe:KPK_4258 hypothetical protein. (206 aa)
dapDPutative tetrahydrodipicolinate N- succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (325 aa)
Sros_6183KEGG: mlo:mlr6716 hypothetical protein. (346 aa)
Sros_6500KEGG: gbm:Gbem_1778 asparagine synthase (glutamine- hydrolyzing). (638 aa)
Sros_6725KEGG: mlo:mll3044 hypothetical protein. (376 aa)
Sros_6748KEGG: hypothetical protein. (168 aa)
Sros_6820Peptidase M20; KEGG: aba:Acid345_0237 peptidase M20. (412 aa)
Sros_7214KEGG: swi:Swit_3995 hypothetical protein. (589 aa)
metE5-methyltetrahydropteroyltriglutamate--homocyste ineS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (738 aa)
Sros_7402Hypothetical protein; KEGG: sme:SM_b20505 putative trifolitoxin immunity protein. (266 aa)
Sros_7561Nucleoside phosphorylase-like protein; KEGG: bja:blr0077 hypothetical protein. (296 aa)
Sros_7680Hippurate hydrolase; KEGG: sal:Sala_2314 peptidase M20D, amidohydrolase. (399 aa)
Sros_7849Aminoacylase; KEGG: dvl:Dvul_0678 amidohydrolase. (419 aa)
Sros_8078KEGG: mxa:MXAN_1973 hypothetical protein. (334 aa)
Sros_8265KEGG: swi:Swit_2076 dihydrodipicolinate reductase. (352 aa)
Sros_8366KEGG: pol:Bpro_4782 Orn/DAP/Arg decarboxylase 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (392 aa)
Sros_8429Dipeptidase; KEGG: scl:sce2952 dipeptidase. (353 aa)
Sros_8431KEGG: bba:Bd1775 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (276 aa)
Sros_8654Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (269 aa)
Sros_9311Aspartate kinase; KEGG: dat:HRM2_35870 LysC; Belongs to the aspartokinase family. (424 aa)
Sros_8776MetE; KEGG: dat:HRM2_34760 MetE. (367 aa)
Sros_9310KEGG: pca:Pcar_1903 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (355 aa)
Sros_8913KEGG: aca:ACP_3389 threonine synthase. (429 aa)
Sros_0061Homoserine O-acetyltransferase; KEGG: bra:BRADO5867 hypothetical protein; Belongs to the AB hydrolase superfamily. MetX family. (338 aa)
Sros_0327Succinyl-diaminopimelate desuccinylase; KEGG: dde:Dde_1186 M20/M25/M40 family peptidase. (434 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (279 aa)
Sros_0440Diaminopimelate decarboxylase-like protein; KEGG: bar:GBAA1438 diaminopimelate decarboxylase. (276 aa)
folD-2Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
Sros_1268Aminoacylase; KEGG: bsu:BSU29290 hypothetical protein. (412 aa)
Sros_1518Peptidase M20; KEGG: ade:Adeh_0863 peptidase M20. (448 aa)
Sros_1634Hypothetical protein; KEGG: acp:A2cp1_2970 asparagine synthase. (552 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (460 aa)
Sros_1638KEGG: gme:Gmet_1629 homoserine dehydrogenase. (430 aa)
Sros_1649L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (336 aa)
Sros_1779KEGG: bbr:BB2432 allantoate amidohydrolase. (387 aa)
Sros_2030Hypothetical protein; KEGG: vei:Veis_2871 aminoglycoside phosphotransferase. (285 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (245 aa)
Sros_2137Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1245 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (268 aa)
Sros_2361KEGG: bja:bll4205 hypothetical protein; Belongs to the DapA family. (351 aa)
Sros_2367Dihydrodipicolinate synthase/N-acetylneuraminate lyase-like protein; KEGG: acp:A2cp1_4217 dihydrodipicolinate synthase. (333 aa)
Sros_2502KEGG: csa:Csal_0030 acetylornithine deacetylase. (418 aa)
Sros_2740KEGG: bsu:BSU02410 homocysteine methyltransferase. (287 aa)
Sros_2788KEGG: afw:Anae109_2667 5,10- methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (310 aa)
Sros_3531KEGG: mes:Meso_2469 asparagine synthase (glutamine- hydrolyzing). (596 aa)
Sros_3753KEGG: hch:HCH_03695 diaminopimelate decarboxylase. (432 aa)
Sros_4169Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (619 aa)
Sros_4248KEGG: swi:Swit_2076 dihydrodipicolinate reductase. (359 aa)
Sros_4372KEGG: mrd:Mrad2831_1541 pyridoxal-5'-phosphate- dependent protein beta subunit. (392 aa)
Sros_4607Putative homoserine kinase type II (protein kinase fold)-like protein; KEGG: eli:ELI_14350 tyrosine protein kinase:aminoglycoside phosphotransferase. (294 aa)
Sros_5213KEGG: rec:RHECIAT_PC0000475 putative aminoglycoside phosphotransferase protein (antibiotic resistance protein). (279 aa)
Sros_5254Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (597 aa)
Sros_5539KEGG: bmn:BMA10247_1403 hypothetical protein. (363 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (451 aa)
Sros_5703Peptidase M20; KEGG: aba:Acid345_0237 peptidase M20. (405 aa)
Sros_5917Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1154 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
Server load: low (18%) [HD]