STRINGSTRING
Sros_1728 Sros_1728 Sros_1727 Sros_1727 Sros_1725 Sros_1725 glyA glyA Sros_1023 Sros_1023 serC serC Sros_0841 Sros_0841 Sros_0724 Sros_0724 Sros_0542 Sros_0542 Sros_0500 Sros_0500 Sros_9200 Sros_9200 Sros_8385 Sros_8385 Sros_8566 Sros_8566 Sros_8912 Sros_8912 serS serS Sros_8241 Sros_8241 Sros_8047 Sros_8047 Sros_7984 Sros_7984 Sros_7858 Sros_7858 Sros_7196 Sros_7196 Sros_7185 Sros_7185 Sros_7152 Sros_7152 Sros_6982 Sros_6982 Sros_6952 Sros_6952 glyA-2 glyA-2 Sros_5832 Sros_5832 Sros_5654 Sros_5654 Sros_5592 Sros_5592 Sros_4971 Sros_4971 Sros_4921 Sros_4921 Sros_4799 Sros_4799 Sros_4493 Sros_4493 Sros_4224 Sros_4224 Sros_4096 Sros_4096 Sros_3925 Sros_3925 Sros_3848 Sros_3848 Sros_3752 Sros_3752 selD selD Sros_3696 Sros_3696 Sros_3644 Sros_3644 Sros_3534 Sros_3534 Sros_3264 Sros_3264
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_1728KEGG: eba:ebA896 cysteine synthase B. (315 aa)
Sros_1727Molybdopterin synthase subunit MoaD; KEGG: scl:sce5755 hypothetical protein. (92 aa)
Sros_1725Mov34/MPN/PAD-1; KEGG: nmu:Nmul_A0971 Mov34/MPN/PAD-1. (138 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
Sros_1023Bifunctional deaminase-reductase-like protein; KEGG: mes:Meso_2196 bifunctional deaminase- reductase-like. (178 aa)
serCPhosphoserine aminotransferase-like protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (369 aa)
Sros_0841KEGG: scl:sce6636 hypothetical protein. (189 aa)
Sros_0724KEGG: scl:sce1370 dihydrofolate reductase family protein. (197 aa)
Sros_0542Phosphoserine phosphatase-like protein; KEGG: afw:Anae109_1214 HAD family hydrolase. (289 aa)
Sros_0500Phosphoserine phosphatase; KEGG: scl:sce0663 hypothetical protein. (407 aa)
Sros_9200KEGG: gsu:GSU0562 hypothetical protein. (183 aa)
Sros_8385KEGG: hch:HCH_02851 molybdopterin/thiamine biosynthesis family protein. (393 aa)
Sros_8566KEGG: scl:sce0438 cystathionine beta-synthase. (456 aa)
Sros_8912Molybdopterin synthase subunit MoaD; KEGG: scl:sce5755 hypothetical protein. (91 aa)
serSSerine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (420 aa)
Sros_8241KEGG: acr:Acry_2572 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (346 aa)
Sros_8047KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
Sros_7984KEGG: dac:Daci_5156 pyridoxal-5'-phosphate- dependent protein beta subunit. (358 aa)
Sros_7858Hypothetical protein; KEGG: ppg:PputGB1_3631 deaminase-reductase domain- containing protein. (199 aa)
Sros_7196KEGG: apa:APP7_1355 putative sulfate transport protein CysZ. (249 aa)
Sros_7185KEGG: mxa:MXAN_1250 RibD domain protein. (190 aa)
Sros_7152KEGG: bpt:Bpet0409 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
Sros_6982KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (183 aa)
Sros_6952KEGG: abc:ACICU_01927 dihydrofolate reductase. (178 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
Sros_5832KEGG: sus:Acid_6255 deaminase-reductase domain- containing protein. (187 aa)
Sros_5654Hypothetical protein; KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (122 aa)
Sros_5592Sulfite reductase beta subunit (hemoprotein)- like protein; KEGG: pae:PA2906 putative oxidoreductase. (473 aa)
Sros_4971Cysteine synthase-like protein; KEGG: mlo:mlr9541 cysteine synthase. (379 aa)
Sros_4921Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa)
Sros_4799Hypothetical protein; KEGG: kpn:KPN_02962 putative bifunctional deaminase- reductase. (89 aa)
Sros_4493Bifunctional deaminase-reductase-like protein; KEGG: rfr:Rfer_2843 bifunctional deaminase- reductase-like. (214 aa)
Sros_4224KEGG: mlo:mlr2503 hypothetical protein. (178 aa)
Sros_4096KEGG: mxa:MXAN_1250 RibD domain protein. (192 aa)
Sros_3925KEGG: sil:SPO3529 serine hydroxymethyltransferase. (417 aa)
Sros_3848KEGG: scl:sce1370 dihydrofolate reductase family protein. (190 aa)
Sros_3752KEGG: bbt:BBta_0633 putative cysteine synthase (O- acetylserine sulfhydrylase) (O-acetylserine (thiol)-lyase) (CSase). (351 aa)
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (354 aa)
Sros_3696KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (181 aa)
Sros_3644KEGG: mlo:mlr0926 hypothetical protein. (190 aa)
Sros_3534KEGG: rlt:Rleg2_4009 D-isomer specific 2- hydroxyacid dehydrogenase NAD-binding. (333 aa)
Sros_3264KEGG: dac:Daci_3022 deaminase-reductase domain- containing protein. (180 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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