STRINGSTRING
Sros_2589 Sros_2589 Sros_3052 Sros_3052 edd edd Sros_4119 Sros_4119 Sros_4565 Sros_4565 ilvD ilvD Sros_8038 Sros_8038 Sros_8041 Sros_8041 ilvC ilvC Sros_8058 Sros_8058 Sros_8059 Sros_8059 Sros_8313 Sros_8313 Sros_8547 Sros_8547 Sros_9103 Sros_9103 Sros_9310 Sros_9310 ilvE ilvE Sros_1638 Sros_1638 Sros_5566 Sros_5566
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_2589KEGG: mlo:mlr3510 threonine dehydratase. (303 aa)
Sros_3052KEGG: vei:Veis_4212 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (584 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (626 aa)
Sros_4119KEGG: aca:ACP_1470 threonine dehydratase catabolic. (319 aa)
Sros_4565KEGG: bur:Bcep18194_B1493 serine/threonine dehydratase. (320 aa)
ilvDKEGG: nmn:NMCC_1068 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (612 aa)
Sros_8038KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (525 aa)
Sros_8041KEGG: nar:Saro_2671 branched-chain amino acid aminotransferase. (364 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa)
Sros_8058KEGG: gur:Gura_3719 acetolactate synthase 3 regulatory subunit. (174 aa)
Sros_8059KEGG: ade:Adeh_1978 acetolactate synthase, large subunit. (578 aa)
Sros_8313KEGG: scl:sce8127 putative acetolactate synthase; Belongs to the TPP enzyme family. (550 aa)
Sros_8547KEGG: gme:Gmet_3072 threonine dehydratase. (402 aa)
Sros_9103KEGG: msl:Msil_2816 thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (577 aa)
Sros_9310KEGG: pca:Pcar_1903 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (355 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (302 aa)
Sros_1638KEGG: gme:Gmet_1629 homoserine dehydrogenase. (430 aa)
Sros_5566KEGG: sus:Acid_1483 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (612 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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