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| | Sros_6635 | Hydantoinase; KEGG: bav:BAV0626 hydantoinase. (470 aa) |
| | dut | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (147 aa) |
| | Sros_6843 | KEGG: gsu:GSU3019 dehydrogenase, E1 component, alpha and beta subunits. (330 aa) |
| | Sros_6845 | KEGG: cko:CKO_03853 hypothetical protein. (396 aa) |
| | nadK-2 | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (285 aa) |
| | Sros_6948 | KEGG: geo:Geob_0200 benzoate-CoA ligase family. (535 aa) |
| | Sros_7043 | Pyruvate dehydrogenase (acetyl-transferring); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa) |
| | Sros_7081 | KEGG: hypothetical protein. (121 aa) |
| | Sros_7161 | KEGG: ank:AnaeK_3243 IMP dehydrogenase family protein. (479 aa) |
| | Sros_7190 | WD40 repeat-domain-containing protein-like protein; KEGG: hypothetical protein. (675 aa) |
| | Sros_7197 | Nucleotide-binding protein implicated in inhibition of septum formation-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (257 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (206 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (136 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa) |
| | Sros_7424 | KEGG: rle:RL3033 hypothetical protein. (114 aa) |
| | Sros_7532 | Hypothetical protein; KEGG: bid:Bind_1566 uridine kinase. (209 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (381 aa) |
| | Sros_7567 | KEGG: rlt:Rleg2_1526 hypothetical protein. (144 aa) |
| | Sros_7578 | KEGG: dac:Daci_4319 glyoxalase/bleomycin resistance protein/dioxygenase. (127 aa) |
| | Sros_7607 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; KEGG: bar:GBAA4346 2',3'-cyclic nucleotide 2'- phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein; Belongs to the 5'-nucleotidase family. (585 aa) |
| | Sros_7697 | KEGG: asa:ASA_2413 ATP-NAD/AcoX kinase. (408 aa) |
| | Sros_7787 | KEGG: hypothetical protein. (120 aa) |
| | Sros_7864 | KEGG: mxa:MXAN_2224 hypothetical protein. (262 aa) |
| | Sros_7944 | KEGG: dal:Dalk_5036 metal dependent phosphohydrolase. (194 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (378 aa) |
| | Sros_7971 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (681 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa) |
| | Sros_8358 | KEGG: mno:Mnod_1819 acyl-CoA thioesterase II. (288 aa) |
| | Sros_8362 | NAD(+) diphosphatase; KEGG: sfu:Sfum_1412 NUDIX hydrolase. (325 aa) |
| | Sros_8363 | KEGG: reh:PHG125 putative siderophore biosynthesis protein. (401 aa) |
| | Sros_8493 | KEGG: sus:Acid_1482 hypothetical protein. (331 aa) |
| | Sros_8577 | KEGG: hypothetical protein LOC100016124. (475 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa) |
| | Sros_8583 | XTP/dITP diphosphohydrolase; KEGG: saz:Sama_1034 nucleoside triphosphate pyrophosphohydrolase. (317 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa) |
| | Sros_8805 | Hypothetical protein; KEGG: gur:Gura_0655 glyoxalase/bleomycin resistance protein/dioxygenase. (133 aa) |
| | Sros_8842 | KEGG: mxa:MXAN_3659 glyoxalase family protein. (118 aa) |
| | purA-2 | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (406 aa) |
| | Sros_8972 | KEGG: bba:Bd0779 pyruvate dehydrogenase E2. (482 aa) |
| | Sros_8974 | Pyruvate dehydrogenase (acetyl-transferring); KEGG: gme:Gmet_2509 dehydrogenase, E1 component. (363 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (81 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (227 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (765 aa) |
| | Sros_8980 | Adenylate cyclase family 3 (some protein contain HAMP domain)-like protein; KEGG: mxa:MXAN_3956 putative adenylate cyclase. (684 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (478 aa) |
| | purM | KEGG: mgm:Mmc1_2316 phosphoribosylformylglycinamidine cyclo-ligase. (341 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (212 aa) |
| | Sros_9281 | KEGG: cvi:CV_1450 hypothetical protein. (113 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (688 aa) |
| | Sros_9176 | KEGG: bha:BH0084 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (260 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (407 aa) |
| | Sros_9077 | KEGG: ppw:PputW619_2543 hypothetical protein. (310 aa) |
| | pyrD-2 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (355 aa) |
| | Sros_0198 | KEGG: pen:PSEEN2314 hypothetical protein. (194 aa) |
| | Sros_0226 | KEGG: rlt:Rleg2_1526 hypothetical protein. (127 aa) |
| | Sros_0228 | KEGG: abb:ABBFA_003338 hypothetical protein. (390 aa) |
| | Sros_0267 | 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase-like protein; KEGG: har:HEAR1476 putative 5'-nucleotidase family protein precursor. (463 aa) |
| | Sros_0315 | WD40 repeat-domain-containing protein-like protein; KEGG: dar:Daro_3599 WD-40 repeat-containing protein. (924 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (279 aa) |
| | purD | KEGG: gbe:GbCGDNIH1_2297 phosphoribosylamine-- glycine ligase; Belongs to the GARS family. (410 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa) |
| | Sros_0391 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (178 aa) |
| | Sros_0450 | KEGG: atc:AGR_L_1193 hypothetical protein. (203 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa) |
| | Sros_0514 | KEGG: mag:amb4350 HD superfamily hydrolase. (201 aa) |
| | Sros_0567 | KEGG: acetyl-coA carboxylase; K01959 pyruvate carboxylase subunit A. (507 aa) |
| | Sros_0685 | Hypothetical protein; KEGG: tmp; thymidylate kinase Tmp1; K00943 dTMP kinase. (211 aa) |
| | Sros_0733 | KEGG: eba:ebA3224 putative ribose-phosphate pyrophosphokinase. (314 aa) |
| | Sros_0777 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (322 aa) |
| | Sros_0805 | Hypothetical protein; KEGG: bid:Bind_1545 thymidylate synthase. (238 aa) |
| | Sros_0814 | KEGG: acp:A2cp1_1002 hypothetical protein. (127 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa) |
| | Sros_0894 | KEGG: scl:sce7039 putative 5'-nucleotidase family protein; Belongs to the 5'-nucleotidase family. (602 aa) |
| | gpmA | Bisphosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa) |
| | coaA | KEGG: mxa:MXAN_2325 pantothenate kinase. (310 aa) |
| | nnrD | YjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimer [...] (533 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa) |
| | Sros_1161 | IMP dehydrogenase/GMP reductase-like protein; KEGG: hap:HAPS_0294 inositol-5-monophosphate dehydrogenase. (372 aa) |
| | guaA | GMP synthase C terminal domain protein; Catalyzes the synthesis of GMP from XMP. (523 aa) |
| | purN | Putative phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (206 aa) |
| | purH | IMP cyclohydrolase; KEGG: acr:Acry_0027 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (514 aa) |
| | folD-2 | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa) |
| | add | KEGG: afw:Anae109_0100 adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (359 aa) |
| | Sros_1328 | KEGG: met:M446_0921 adenylate/guanylate cyclase. (330 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa) |
| | Sros_1389 | Mannose-6-phosphate isomerase; KEGG: tmz:Tmz1t_0879 KpsF/GutQ family protein. (368 aa) |
| | Sros_1406 | KEGG: msl:Msil_2124 serine/threonine protein kinase. (716 aa) |
| | Sros_1444 | KEGG: rme:Rmet_2699 acetyl-CoA synthetase. (681 aa) |
| | Sros_1578 | KEGG: hypothetical protein. (698 aa) |
| | purC | KEGG: psa:PST_2788 phosphoribosylaminoimidazole- succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (276 aa) |
| | atpB | F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (263 aa) |
| | atpE | ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (77 aa) |
| | atpF | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (182 aa) |
| | atpH | F0F1-type ATP synthase delta subunit-like protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (270 aa) |
| | atpA | H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (549 aa) |
| | atpG | ATP synthase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (299 aa) |
| | atpD | H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (475 aa) |
| | atpC | ATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | Sros_1674 | Hypothetical protein; KEGG: nar:Saro_0591 phosphopantothenate-cysteine ligase / phosphopantothenoylcysteine decarboxylase. (182 aa) |
| | Sros_1696 | KEGG: gbm:Gbem_0558 methylmalonyl-CoA epimerase. (140 aa) |
| | Sros_1705 | KEGG: sus:Acid_6330 hypothetical protein. (209 aa) |
| | Sros_1710 | KEGG: hha:Hhal_0938 hypothetical protein; Belongs to the UPF0301 (AlgH) family. (192 aa) |
| | Sros_1721 | KEGG: avi:Avi_2845 pyrazinamidase/nicotinamidase. (190 aa) |
| | Sros_1722 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (428 aa) |
| | Sros_1731 | KEGG: dal:Dalk_1857 hypothetical protein. (263 aa) |
| | Sros_1735 | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (212 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (256 aa) |
| | Sros_1890 | KEGG: rce:RC1_1843 propionate--CoA ligase. (695 aa) |
| | Sros_1993 | KEGG: cti:RALTA_B0485 putative glyoxalase/dioxygenase. (113 aa) |
| | Sros_2129 | KEGG: xac:XAC1253 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (317 aa) |
| | Sros_2149 | KEGG: dar:Daro_0369 hypothetical protein. (340 aa) |
| | Sros_2175 | Competence/damage-inducible protein cinA; KEGG: hypothetical protein; Belongs to the CinA family. (167 aa) |
| | Sros_2205 | KEGG: gsu:GSU3019 dehydrogenase, E1 component, alpha and beta subunits. (307 aa) |
| | Sros_2207 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; KEGG: nmu:Nmul_A0856 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase. (417 aa) |
| | Sros_2294 | KEGG: ank:AnaeK_0190 histidine triad (HIT) protein. (117 aa) |
| | Sros_2349 | KEGG: aba:Acid345_0225 deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (410 aa) |
| | Sros_2413 | Aldolase; KEGG: dol:Dole_1897 aldolase. (295 aa) |
| | nadE | NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (597 aa) |
| | Sros_2617 | KEGG: gbm:Gbem_1504 glutamine amidotransferase class-I. (233 aa) |
| | Sros_2644 | KEGG: sus:Acid_0914 dihydrolipoyllysine-residue succinyltransferase. (479 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (384 aa) |
| | pfp | Diphosphate--fructose-6-phosphate1-phosphotransf erase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa) |
| | atpG-2 | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (306 aa) |
| | pyrB | Aspartate carbamoyltransferase; KEGG: scl:sce3822 hypothetical protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (310 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (431 aa) |
| | carA | Carbamoyl-phosphate synthase (glutamine- hydrolyzing); KEGG: hch:HCH_01227 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (400 aa) |
| | carB | KEGG: geo:Geob_3271 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1097 aa) |
| | Sros_2809 | KEGG: pca:Pcar_1295 2-polyprenylphenol hydroxylase/flavodoxin oxidoreductase. (291 aa) |
| | pyrD | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (324 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (237 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (234 aa) |
| | Sros_2815 | Phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (413 aa) |
| | Sros_2953 | KEGG: mxa:MXAN_6299 pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (563 aa) |
| | cmk | KEGG: sus:Acid_0051 cytidylate kinase. (218 aa) |
| | Sros_3041 | Putative lyase; KEGG: cti:RALTA_B0885 putative lyase. (138 aa) |
| | Sros_3110 | KEGG: sus:Acid_1350 hypothetical protein. (232 aa) |
| | Sros_3235 | KEGG: mxa:MXAN_2887 hypothetical protein. (276 aa) |
| | Sros_3349 | Hypothetical protein. (210 aa) |
| | Sros_3372 | Glucokinase; KEGG: sde:Sde_1018 glucokinase; Belongs to the bacterial glucokinase family. (318 aa) |
| | nadE-2 | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (276 aa) |
| | Sros_3660 | KEGG: plu:plu1218 hypothetical protein. (411 aa) |
| | Sros_3763 | KEGG: bxe:Bxe_A1419 benzoate-coenzyme A ligase. (522 aa) |
| | Sros_4090 | KEGG: bbr:BB4366 hypothetical protein. (129 aa) |
| | Sros_4111 | KEGG: smt:Smal_3751 glyoxalase/bleomycin resistance protein/dioxygenase. (122 aa) |
| | Sros_4132 | KEGG: mxa:MXAN_3659 glyoxalase family protein. (133 aa) |
| | accD | Acetyl-CoA carboxylase alpha subunit-like protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (552 aa) |
| | Sros_4193 | KEGG: gdj:Gdia_2052 acetyl-CoA carboxylase, biotin carboxylase. (450 aa) |
| | Sros_4316 | KEGG: aba:Acid345_2541 glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | Sros_4383 | KEGG: scl:sce2686 WD repeat-containing protein. (65 aa) |
| | Sros_4439 | KEGG: adenylosuccinate lyase; K01756 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (476 aa) |
| | Sros_4529 | CTP synthase; KEGG: ent:Ent638_1664 hypothetical protein. (251 aa) |
| | Sros_4614 | WD40 repeat-domain-containing protein-like protein; KEGG: dar:Daro_3599 WD-40 repeat-containing protein. (919 aa) |
| | Sros_4824 | KEGG: bid:Bind_0505 oxidoreductase FAD/NAD(P)- binding subunit. (272 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (265 aa) |
| | Sros_5068 | KEGG: rlt:Rleg2_1526 hypothetical protein. (150 aa) |
| | Sros_5116 | KEGG: rle:RL3033 hypothetical protein. (240 aa) |
| | Sros_5120 | WD40 repeat-domain-containing protein-like protein; KEGG: hypothetical protein. (490 aa) |
| | Sros_5137 | KEGG: rle:RL3033 hypothetical protein. (130 aa) |
| | Sros_5138 | GMP synthase - Glutamine amidotransferase domain- like protein; KEGG: gbm:Gbem_1504 glutamine amidotransferase class-I. (238 aa) |
| | Sros_5538 | KEGG: sus:Acid_1482 hypothetical protein. (289 aa) |
| | Sros_5564 | KEGG: sus:Acid_1482 hypothetical protein. (293 aa) |
| | Sros_5763 | KEGG: rle:RL3033 hypothetical protein. (228 aa) |
| | Sros_5990 | Protein related to lactoylglutathione lyase- like protein; KEGG: spl:Spea_3990 glyoxalase/bleomycin resistance protein/dioxygenase. (307 aa) |
| | Sros_6015 | KEGG: sfu:Sfum_1952 phosphoglucose isomerase (PGI); Belongs to the GPI family. (542 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa) |
| | pgk | KEGG: bsu:BSU33930 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (395 aa) |
| | Sros_6038 | KEGG: sus:Acid_7375 glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | nadK | Sugar kinase-like protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (301 aa) |
| | Sros_6106 | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (785 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa) |
| | Sros_6130 | KEGG: sfu:Sfum_2126 histidine triad (HIT) protein. (187 aa) |
| | Sros_6154 | Hypothetical protein. (106 aa) |
| | Sros_6227 | WD40 repeat-domain-containing protein-like protein; KEGG: scl:sce8391 WD repeat-containing protein. (943 aa) |
| | Sros_6268 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (331 aa) |
| | Sros_6580 | Acetyl-CoA carboxylase beta subunit-like protein; KEGG: acetyl-coA carboxylase; K01959 pyruvate carboxylase subunit A. (514 aa) |
| | Sros_6582 | Hypothetical protein. (193 aa) |
| | Sros_6597 | KEGG: hne:HNE_3149 thymidine kinase. (210 aa) |
