STRINGSTRING
murA murA hemC hemC Sros_0926 Sros_0926 Sros_1376 Sros_1376 Sros_1675 Sros_1675 menA menA miaA miaA Sros_2336 Sros_2336 Sros_2380 Sros_2380 Sros_2587 Sros_2587 nadA nadA thiE thiE metK metK Sros_2833 Sros_2833 ribH ribH murA-2 murA-2 Sros_2948 Sros_2948 Sros_3288 Sros_3288 Sros_3413 Sros_3413 Sros_3417 Sros_3417 Sros_3708 Sros_3708 Sros_3714 Sros_3714 Sros_3752 Sros_3752 Sros_3775 Sros_3775 Sros_3828 Sros_3828 Sros_4971 Sros_4971 Sros_5884 Sros_5884 Sros_5948 Sros_5948 ctaB ctaB Sros_6184 Sros_6184 Sros_6906 Sros_6906 Sros_8009 Sros_8009 Sros_8279 Sros_8279 aroA aroA Sros_8524 Sros_8524 Sros_8563 Sros_8563 Sros_8926 Sros_8926 Sros_9173 Sros_9173
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murAUDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (422 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (306 aa)
Sros_0926Uncharacterized protein possibly involved in utilization of glycolate and propanediol-like protein; KEGG: rpt:Rpal_4963 protein of unknown function DUF336. (183 aa)
Sros_1376KEGG: swi:Swit_0717 FO synthase. (867 aa)
Sros_1675KEGG: mmr:Mmar10_2358 ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (196 aa)
menA1,4-dihydroxy-2-naphthoateoctaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (292 aa)
miaAtRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (301 aa)
Sros_2336Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa)
Sros_2380KEGG: mno:Mnod_0157 glutathione S-transferase domain-containing protein. (313 aa)
Sros_2587Cystathionine gamma-synthase; KEGG: cko:CKO_04984 hypothetical protein. (390 aa)
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (384 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (213 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa)
Sros_2833KEGG: sus:Acid_4223 riboflavin synthase subunit alpha. (202 aa)
ribHRiboflavin synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (156 aa)
murA-2UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (438 aa)
Sros_2948KEGG: rpb:RPB_2044 hypothetical protein. (516 aa)
Sros_3288KEGG: rce:RC1_0952 3-deoxy-7-phosphoheptulonate synthase; Belongs to the class-II DAHP synthase family. (443 aa)
Sros_3413Spermidine synthase-like protein; KEGG: sus:Acid_3582 hypothetical protein. (681 aa)
Sros_3417Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (277 aa)
Sros_3708Hypothetical protein; KEGG: eba:ebA3963 1,4-dihydroxy-2-naphthoate octaprenyltransferase. (310 aa)
Sros_3714Geranylgeranyl pyrophosphate synthase-like protein; KEGG: sfu:Sfum_1417 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (350 aa)
Sros_3752KEGG: bbt:BBta_0633 putative cysteine synthase (O- acetylserine sulfhydrylase) (O-acetylserine (thiol)-lyase) (CSase). (351 aa)
Sros_37753-deoxy-7-phosphoheptulonate synthase; KEGG: ppf:Pput_3849 phospho-2-dehydro-3- deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (388 aa)
Sros_3828Phytoene synthase; KEGG: sus:Acid_1266 farnesyl-diphosphate farnesyltransferase. (299 aa)
Sros_4971Cysteine synthase-like protein; KEGG: mlo:mlr9541 cysteine synthase. (379 aa)
Sros_5884Cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: bid:Bind_0386 cob(I)alamin adenosyltransferase. (200 aa)
Sros_5948KEGG: scl:sce0081 hypothetical protein. (301 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (317 aa)
Sros_6184KEGG: gdj:Gdia_0950 protein of unknown function DUF336. (133 aa)
Sros_6906Geranylgeranyl pyrophosphate synthase-like protein; KEGG: sfu:Sfum_1417 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (346 aa)
Sros_8009KEGG: sfu:Sfum_2670 cystathionine gamma-synthase. (406 aa)
Sros_8279KEGG: rce:RC1_3391 transferase, putative. (297 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (425 aa)
Sros_8524Z-farnesyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (255 aa)
Sros_8563KEGG: afw:Anae109_3845 cystathionine gamma-lyase. (379 aa)
Sros_8926KEGG: dal:Dalk_3152 protein of unknown function DUF62. (270 aa)
Sros_9173Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (283 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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