STRINGSTRING
Sros_0506 Sros_0506 hemL hemL Sros_0560 Sros_0560 Sros_0634 Sros_0634 Sros_0651 Sros_0651 Sros_0916 Sros_0916 Sros_0938 Sros_0938 gpmA gpmA truA truA glmM glmM nnrD nnrD Sros_1141 Sros_1141 groL groL Sros_1242 Sros_1242 Sros_1261 Sros_1261 Sros_1282 Sros_1282 purE purE Sros_1387 Sros_1387 Sros_1389 Sros_1389 rbsD rbsD Sros_1503 Sros_1503 Sros_1602 Sros_1602 Sros_1630 Sros_1630 Sros_1696 Sros_1696 Sros_1703 Sros_1703 murI murI truB truB dapF dapF nanE nanE Sros_2594 Sros_2594 Sros_2736 Sros_2736 Sros_2830 Sros_2830 Sros_2883 Sros_2883 hisA hisA Sros_2943 Sros_2943 Sros_2996 Sros_2996 Sros_2997 Sros_2997 Sros_3086 Sros_3086 Sros_3135 Sros_3135 Sros_3187 Sros_3187 Sros_3188 Sros_3188 Sros_3192 Sros_3192 Sros_3235 Sros_3235 idi idi Sros_9365 Sros_9365 topA topA Sros_9074 Sros_9074 groL-3 groL-3 Sros_8906 Sros_8906 Sros_8808 Sros_8808 Sros_8584 Sros_8584 Sros_8512 Sros_8512 Sros_8492 Sros_8492 Sros_8322 Sros_8322 Sros_8255 Sros_8255 Sros_8216 Sros_8216 Sros_8164 Sros_8164 Sros_8141 Sros_8141 Sros_7931 Sros_7931 Sros_7767 Sros_7767 Sros_7331 Sros_7331 Sros_7320 Sros_7320 tig tig Sros_7175 Sros_7175 Sros_7084 Sros_7084 Sros_7080 Sros_7080 menC-3 menC-3 Sros_6638 Sros_6638 Sros_6615 Sros_6615 Sros_6462 Sros_6462 Sros_6243 Sros_6243 araA araA Sros_6104 Sros_6104 Sros_6099 Sros_6099 tpiA tpiA Sros_6015 Sros_6015 Sros_6004 Sros_6004 Sros_5997 Sros_5997 Sros_5894 Sros_5894 Sros_5867 Sros_5867 Sros_5866 Sros_5866 menC-2 menC-2 Sros_5639 Sros_5639 Sros_5593 Sros_5593 Sros_5565 Sros_5565 Sros_5533 Sros_5533 menC menC Sros_5198 Sros_5198 Sros_4995 Sros_4995 Sros_4977 Sros_4977 Sros_4855 Sros_4855 Sros_4753 Sros_4753 Sros_4608 Sros_4608 Sros_4590 Sros_4590 groL-2 groL-2 Sros_4294 Sros_4294 Sros_4053 Sros_4053 Sros_3812 Sros_3812 Sros_3810 Sros_3810 Sros_3710 Sros_3710 Sros_3665 Sros_3665 trpF trpF icmF icmF Sros_3503 Sros_3503 Sros_3303 Sros_3303 gyrB gyrB gyrA gyrA Sros_0105 Sros_0105 Sros_3328 Sros_3328 pheA pheA xylA xylA Sros_0374 Sros_0374 Sros_0428 Sros_0428 Sros_0430 Sros_0430
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Sros_0506S-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (371 aa)
hemLKEGG: aeh:Mlg_0806 glutamate-1-semialdehyde 2,1- aminomutase. (437 aa)
Sros_05605-carboxymethyl-2-hydroxymuconateDelta- isomerase; KEGG: bxe:Bxe_C0991 putative fumarylacetoacetate (FAA) hydrolase. (281 aa)
Sros_0634dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (216 aa)
Sros_0651KEGG: bch:Bcen2424_6650 dTDP-4-dehydrorhamnose 3,5- epimerase. (187 aa)
Sros_0916Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands. (169 aa)
Sros_0938KEGG: kpn:KPN_00344 maltodextrin glucosidase; Belongs to the glycosyl hydrolase 13 family. (590 aa)
gpmABisphosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa)
truAtRNA-pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (360 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (451 aa)
nnrDYjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimer [...] (533 aa)
Sros_1141Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (371 aa)
groLChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (541 aa)
Sros_1242KEGG: ade:Adeh_1832 methylmalonyl-CoA mutase. (135 aa)
Sros_1261KEGG: aca:ACP_3478 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (321 aa)
Sros_1282Glucose-1,6-bisphosphate synthase; KEGG: scl:sce4837 putative phosphoglucomutase/phosphomannomutase. (547 aa)
purEPhosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (167 aa)
Sros_1387Phosphomannomutase; KEGG: gbm:Gbem_1134 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III. (450 aa)
Sros_1389Mannose-6-phosphate isomerase; KEGG: tmz:Tmz1t_0879 KpsF/GutQ family protein. (368 aa)
rbsDRbsD; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (129 aa)
Sros_1503KEGG: mpo:Mpop_2993 aldose 1-epimerase. (317 aa)
Sros_1602KEGG: mes:Meso_2673 malto-oligosyltrehalose synthase. (727 aa)
Sros_1630KEGG: mrd:Mrad2831_1598 trehalose synthase. (562 aa)
Sros_1696KEGG: gbm:Gbem_0558 methylmalonyl-CoA epimerase. (140 aa)
Sros_1703KEGG: scl:sce7549 isobutyryl-CoA mutase. (555 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (276 aa)
truBtRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (299 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (268 aa)
nanEN-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (229 aa)
Sros_2594Hypothetical protein; KEGG: swi:Swit_2804 membrane-like protein. (683 aa)
Sros_2736Hypothetical protein; KEGG: ppw:PputW619_4600 NUDIX hydrolase. (196 aa)
Sros_2830Ribulose-phosphate 3-epimerase; KEGG: gme:Gmet_0067 ribulose-5-phosphate 3- epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (218 aa)
Sros_2883RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (309 aa)
hisAPhosphoribosylanthranilate isomerase; KEGG: plu:plu0797 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase. (240 aa)
Sros_2943Hypothetical protein; KEGG: ank:AnaeK_4060 DsbA oxidoreductase. (254 aa)
Sros_2996KEGG: oca:OCAR_7243 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. (621 aa)
Sros_2997KEGG: ade:Adeh_0182 chorismate mutase. (119 aa)
Sros_3086Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pca:Pcar_0266 glutamate-1-semialdehyde-2,1- aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)
Sros_3135Hypothetical protein; KEGG: sde:Sde_1385 HesB/YadR/YfhF. (228 aa)
Sros_3187KEGG: rru:Rru_A2480 methylmalonyl-CoA mutase. (633 aa)
Sros_3188KEGG: azc:AZC_1772 methylmalonyl-CoA mutase. (725 aa)
Sros_3192KEGG: scl:sce4636 hypothetical protein. (560 aa)
Sros_3235KEGG: mxa:MXAN_2887 hypothetical protein. (276 aa)
idiIsopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (193 aa)
Sros_9365KEGG: sme:SM_b20249 putative myo-inositol-1- phosphate synthase. (359 aa)
topADNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] (883 aa)
Sros_9074KEGG: hne:HNE_3461 metallo-beta-lactamase family protein. (637 aa)
groL-3Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (541 aa)
Sros_8906KEGG: scl:sce4225 hypothetical protein. (214 aa)
Sros_8808KEGG: rsq:Rsph17025_2978 alpha amylase, catalytic region. (552 aa)
Sros_8584Hypothetical protein; KEGG: pen:PSEEN0430 peptidyl-prolyl cis-trans isomerase A. (206 aa)
Sros_8512KEGG: sun:SUN_0947 hypothetical protein. (128 aa)
Sros_8492KEGG: sus:Acid_1480 myo-inositol catabolism IolB domain-containing protein. (273 aa)
Sros_8322KEGG: mxa:MXAN_3507 UDP-glucose 4-epimerase. (314 aa)
Sros_8255KEGG: vei:Veis_3268 xylose isomerase domain- containing protein. (335 aa)
Sros_8216KEGG: spe:Spro_0639 5-carboxymethyl-2- hydroxymuconate delta-isomerase. (281 aa)
Sros_8164KEGG: bsu:BSU38250 hypothetical protein. (213 aa)
Sros_8141KEGG: mxa:MXAN_3684 trehalose synthase. (567 aa)
Sros_7931KEGG: reh:H16_B2289 3-carboxy-cis,cis-muconate cyclo-isomerase. (452 aa)
Sros_7767Hypothetical protein. (253 aa)
Sros_7331Hypothetical protein; KEGG: sbp:Sbal223_2107 NERD domain protein. (277 aa)
Sros_7320KEGG: gme:Gmet_2621 ribose/galactose isomerase. (169 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (468 aa)
Sros_7175KEGG: tbd:Tbd_2152 peptidyl-prolyl cis-trans isomerase. (124 aa)
Sros_7084DNA topoisomerase (ATP-hydrolyzing); KEGG: bha:BH0006 DNA gyrase subunit B. (690 aa)
Sros_7080KEGG: baa:BA_0601 DNA gyrase/topoisomerase IV, subunit A. (831 aa)
menC-3O-succinylbenzoic acid synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (366 aa)
Sros_6638KEGG: smt:Smal_2969 DsbA oxidoreductase. (231 aa)
Sros_6615KEGG: dsh:Dshi_1038 Asp/Glu racemase. (247 aa)
Sros_6462KEGG: bsu:BSU30780 O-succinylbenzoate-CoA synthase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (334 aa)
Sros_6243KEGG: sus:Acid_5959 hypothetical protein. (104 aa)
araAL-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (493 aa)
Sros_6104Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family-like protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (289 aa)
Sros_6099KEGG: bra:BRADO3996 peptidyl-prolyl cis-trans isomerase A (rotamase A). (294 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
Sros_6015KEGG: sfu:Sfum_1952 phosphoglucose isomerase (PGI); Belongs to the GPI family. (542 aa)
Sros_60044-hydroxyproline epimerase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity. (333 aa)
Sros_5997KEGG: slo:Shew_2361 proline racemase; Belongs to the proline racemase family. (336 aa)
Sros_5894Aminotransferase; KEGG: nar:Saro_0248 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (407 aa)
Sros_5867FKBP-type peptidyl-prolyl cis-trans isomerase 1- like protein; KEGG: scl:sce4776 peptidylprolyl isomerase. (319 aa)
Sros_5866FKBP-type peptidyl-prolyl cis-trans isomerase 1- like protein; KEGG: scl:sce3796 FKBP-type peptidyl-prolyl cis- trans isomerase. (301 aa)
menC-2O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (366 aa)
Sros_5639KEGG: ccs:CCNA_00083 phosphoglucomutase/phosphomannomutase. (545 aa)
Sros_5593KEGG: bmj:BMULJ_01675 precorrin-8X methylmutase. (208 aa)
Sros_5565KEGG: sus:Acid_1480 myo-inositol catabolism IolB domain-containing protein. (282 aa)
Sros_5533Protein-disulfide isomerase-like protein; KEGG: sus:Acid_5523 DsbA oxidoreductase. (192 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (369 aa)
Sros_5198KEGG: dat:HRM2_29090 hypothetical protein. (251 aa)
Sros_4995KEGG: dol:Dole_2015 mannose-6-phosphate isomerase, class I. (396 aa)
Sros_4977Protein-disulfide isomerase-like protein; KEGG: mxa:MXAN_4966 putative lipoprotein. (224 aa)
Sros_4855Asp/Glu racemase; KEGG: bur:Bcep18194_B2040 Asp/Glu racemase. (258 aa)
Sros_4753KEGG: scl:sce1376 DSBA oxidoreductase. (219 aa)
Sros_4608KEGG: mno:Mnod_6025 fumarylacetoacetate (FAA) hydrolase. (222 aa)
Sros_4590KEGG: bxe:Bxe_A3003 aspartate racemase; Belongs to the aspartate/glutamate racemases family. (301 aa)
groL-2Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (541 aa)
Sros_4294Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family-like protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (252 aa)
Sros_4053KEGG: scl:sce5042 hypothetical protein. (412 aa)
Sros_3812KEGG: sal:Sala_3209 phosphoheptose isomerase. (225 aa)
Sros_3810KEGG: reh:PHG074 putative sedoheptulose 7-phosphate isomerase. (214 aa)
Sros_3710KEGG: scl:sce4636 hypothetical protein. (577 aa)
Sros_3665KEGG: bsu:BSU37740 hypothetical protein. (187 aa)
trpFKEGG: sil:SPO0806 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (211 aa)
icmFMethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1073 aa)
Sros_3503KEGG: bar:GBAA2834 proline racemase, putative; Belongs to the proline racemase family. (333 aa)
Sros_3303KEGG: eum:ECUMN_4406 putative aldose-1-epimerase. (297 aa)
gyrBDNA topoisomerase (ATP-hydrolyzing); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent [...] (647 aa)
gyrADNA topoisomerase (ATP-hydrolyzing); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent [...] (836 aa)
Sros_0105Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (178 aa)
Sros_3328KEGG: eck:EC55989_0412 maltodextrin glucosidase. (596 aa)
pheAKEGG: ade:Adeh_1779 prephenate dehydratase. (306 aa)
xylAKEGG: aba:Acid345_0903 xylose isomerase; Belongs to the xylose isomerase family. (383 aa)
Sros_0374KEGG: mxa:MXAN_1101 UDP-N-acetylglucosamine 2- epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (389 aa)
Sros_0428KEGG: acr:Acry_2987 L-rhamnose isomerase. (390 aa)
Sros_0430Putative L-arabinose isomerase protein; Catalyzes the conversion of L-arabinose to L-ribulose. (475 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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