STRINGSTRING
clpX-2 clpX-2 Sros_7388 Sros_7388 Sros_7389 Sros_7389 Sros_7563 Sros_7563 Sros_7758 Sros_7758 Sros_7895 Sros_7895 smc smc Sros_8000 Sros_8000 Sros_8073 Sros_8073 Sros_8359 Sros_8359 Sros_8376 Sros_8376 Sros_8411 Sros_8411 Sros_8440 Sros_8440 Sros_8455 Sros_8455 ychF ychF Sros_8689 Sros_8689 Sros_8908 Sros_8908 Sros_8943 Sros_8943 Sros_9132 Sros_9132 Sros_9148 Sros_9148 ftsH-3 ftsH-3 Sros_9252 Sros_9252 Sros_9384 Sros_9384 Sros_9348 Sros_9348 Sros_0020 Sros_0020 Sros_0027 Sros_0027 Sros_0031 Sros_0031 Sros_0140 Sros_0140 Sros_0147 Sros_0147 kdpB kdpB Sros_0462 Sros_0462 Sros_0463 Sros_0463 clpB clpB Sros_0979 Sros_0979 Sros_1131 Sros_1131 Sros_1151 Sros_1151 Sros_1236 Sros_1236 Sros_1381 Sros_1381 Sros_1408 Sros_1408 Sros_1409 Sros_1409 Sros_1410 Sros_1410 Sros_1433 Sros_1433 Sros_1585 Sros_1585 Sros_1792 Sros_1792 Sros_1928 Sros_1928 Sros_2403 Sros_2403 Sros_2699 Sros_2699 Sros_2843 Sros_2843 Sros_2860 Sros_2860 uvrB uvrB Sros_3182 Sros_3182 lon lon clpX clpX Sros_3676 Sros_3676 Sros_3699 Sros_3699 Sros_3884 Sros_3884 Sros_3911 Sros_3911 clpB-2 clpB-2 Sros_4092 Sros_4092 Sros_4682 Sros_4682 Sros_4803 Sros_4803 Sros_4812 Sros_4812 Sros_4832 Sros_4832 ftsH ftsH Sros_5180 Sros_5180 Sros_5501 Sros_5501 Sros_5718 Sros_5718 Sros_5818 Sros_5818 Sros_5885 Sros_5885 arc arc Sros_5981 Sros_5981 Sros_6021 Sros_6021 uvrA uvrA Sros_6097 Sros_6097 ruvB ruvB ruvA ruvA Sros_6204 Sros_6204 Sros_6448 Sros_6448 Sros_6473 Sros_6473 Sros_6483 Sros_6483 Sros_6737 Sros_6737 Sros_6756 Sros_6756 Sros_6762 Sros_6762 Sros_7100 Sros_7100 ftsH-2 ftsH-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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clpX-2ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (426 aa)
Sros_7388KEGG: aba:Acid345_2064 hypothetical protein. (440 aa)
Sros_7389KEGG: aba:Acid345_2063 hypothetical protein. (219 aa)
Sros_7563ATPase-like protein; KEGG: mpt:Mpe_A0007 ATPase. (409 aa)
Sros_7758ATPase; KEGG: afw:Anae109_2702 ATPase. (283 aa)
Sros_7895KEGG: scl:sce6315 excinuclease ABC subunit A. (768 aa)
smcChromosome segregation SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1227 aa)
Sros_8000KEGG: tgr:Tgr7_3183 ATP-dependent DNA helicase RecG. (723 aa)
Sros_8073ATPase-like protein; KEGG: scl:sce0822 chromosome partition protein fragment. (362 aa)
Sros_8359Superfamily I DNA and RNA helicase-like protein; KEGG: gsu:GSU3411 ATP-dependent DNA helicase PcrA, putative. (689 aa)
Sros_8376Superfamily I DNA and RNA helicase-like protein; KEGG: vei:Veis_3742 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1228 aa)
Sros_8411Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (380 aa)
Sros_8440KEGG: mgm:Mmc1_1352 UvrD/REP helicase. (685 aa)
Sros_8455KEGG: CLPC1; chaperone, Hsp100 family, ClpC-type; K03696 ATP-dependent Clp protease ATP-binding subunit ClpC. (192 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (362 aa)
Sros_8689KEGG: rpe:RPE_2170 hypothetical protein. (663 aa)
Sros_8908Superfamily I DNA and RNA helicase-like protein; KEGG: aeh:Mlg_1110 hypothetical protein. (672 aa)
Sros_8943KEGG: tbd:Tbd_0502 cation-transporting ATPase, E1- E2 type. (797 aa)
Sros_9132Hypothetical protein. (447 aa)
Sros_9148KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. (835 aa)
ftsH-3Microtubule-severing ATPase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (656 aa)
Sros_9252KEGG: bra:BRADO0193 chromosome partitioning protein. (330 aa)
Sros_9384KEGG: bsu:BSU40970 chromosome partitioning protein; transcriptional regulator. (308 aa)
Sros_9348Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (451 aa)
Sros_0020KEGG: bar:GBAA3859 heavy metal-transporting ATPase. (746 aa)
Sros_0027KEGG: scl:sce7794 hypothetical protein. (371 aa)
Sros_0031KEGG: scl:sce5713 cell division cycle protein 48- related protein; Belongs to the AAA ATPase family. (448 aa)
Sros_0140Hypothetical protein. (138 aa)
Sros_0147ATPase involved in chromosome partitioning-like protein; KEGG: Hypothetical protein CBG04386. (899 aa)
kdpBK+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (710 aa)
Sros_0462KEGG: mxa:MXAN_5818 anion-transporting ATPase. (389 aa)
Sros_0463KEGG: afw:Anae109_0972 chromosome partitioning-like ATPase. (360 aa)
clpBATPase AAA-2; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (860 aa)
Sros_0979ATP-dependent protease Clp ATPase subunit-like protein; KEGG: bba:Bd3753 ATP-dependent protease ATP-binding subunit. (123 aa)
Sros_1131KEGG: dal:Dalk_0113 SMC domain protein. (450 aa)
Sros_1151KEGG: hypothetical protein. (386 aa)
Sros_1236KEGG: bsu:BSU06610 ATP-dependent DNA helicase. (762 aa)
Sros_1381KEGG: ATPase, AAA family protein. (759 aa)
Sros_1408KEGG: hne:HNE_1205 AAA family ATPase. (336 aa)
Sros_1409KEGG: scl:sce1390 hypothetical protein. (386 aa)
Sros_1410KEGG: bha:BH0729 hypothetical protein. (223 aa)
Sros_1433KEGG: hch:HCH_00429 cation transport ATPase. (1482 aa)
Sros_1585KEGG: scl:sce5242 hypothetical protein. (1726 aa)
Sros_1792KEGG: ppw:PputW619_2496 excinuclease ABC, A subunit. (824 aa)
Sros_1928MoxR-like protein ATPase-like protein; KEGG: dvm:DvMF_2569 ATPase associated with various cellular activities AAA_3. (353 aa)
Sros_2403GTPase subunit of restriction endonuclease-like protein; KEGG: efe:EFER_3105 putative 5-methylcytosine- specific restriction enzyme with GTPase activity. (822 aa)
Sros_2699KEGG: sus:Acid_5915 arsenite-activated ATPase ArsA. (389 aa)
Sros_2843KEGG: rpe:RPE_1657 ATPase associated with various cellular activities, AAA_5. (288 aa)
Sros_2860KEGG: bha:BH0604 methanol dehydrogenase regulatory protein. (325 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (711 aa)
Sros_3182KEGG: hypothetical protein. (379 aa)
lonEndopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (789 aa)
clpXATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (431 aa)
Sros_3676KEGG: xac:XAC1186 excinuclease ABC subunit A. (880 aa)
Sros_3699KEGG: bar:GBAA3859 heavy metal-transporting ATPase. (745 aa)
Sros_3884ATPase; KEGG: mrd:Mrad2831_1397 ATPase. (391 aa)
Sros_3911KEGG: bha:BH0604 methanol dehydrogenase regulatory protein. (325 aa)
clpB-2ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (868 aa)
Sros_4092Superfamily I DNA and RNA helicase-like protein; KEGG: bar:GBAA2814 UvrD/Rep helicase family protein. (670 aa)
Sros_4682KEGG: acr:Acry_1121 ATPase, P-type (transporting), HAD superfamily, subfamily IC. (818 aa)
Sros_4803KEGG: mno:Mnod_6169 heavy metal translocating P- type ATPase. (762 aa)
Sros_4812KEGG: sat:SYN_02760 Mg(2+) transport ATPase, P-type. (893 aa)
Sros_4832KEGG: ade:Adeh_2259 cation transporting P-type ATPase. (863 aa)
ftsHMicrotubule-severing ATPase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (641 aa)
Sros_5180Superfamily I DNA and RNA helicase-like protein; KEGG: bar:GBAA2814 UvrD/Rep helicase family protein. (715 aa)
Sros_5501ATPase; KEGG: aav:Aave_1063 ATPase. (334 aa)
Sros_5718Molecular chaperone HSP90 family-like protein; KEGG: mxa:MXAN_1393 ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein. (872 aa)
Sros_5818Superfamily I DNA and RNA helicase-like protein; KEGG: bar:GBAA2814 UvrD/Rep helicase family protein. (766 aa)
Sros_5885KEGG: rso:RS03742 chelatase protein. (713 aa)
arcATP-dependent 26S proteasome regulatory subunit- like protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (587 aa)
Sros_5981KEGG: eli:ELI_12745 metal-sulfur cluster biosynthetic enzyme. (121 aa)
Sros_6021KEGG: hypothetical protein; K03696 ATP-dependent Clp protease ATP-binding subunit ClpC. (196 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (946 aa)
Sros_6097KEGG: gsu:GSU2067 recombination factor protein RarA. (436 aa)
ruvBHolliday junction DNA helicase B; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (352 aa)
ruvAHolliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (206 aa)
Sros_6204KEGG: mxa:MXAN_2795 nogalamycin resistance protein SnorO. (750 aa)
Sros_6448Hypothetical protein; KEGG: vesicular transport-associated repeat protein. (1062 aa)
Sros_6473KEGG: ecm:EcSMS35_3512 ATPase, AAA family. (355 aa)
Sros_6483ATP-dependent Zn protease-like protein; KEGG: cell division protein FtsH; Belongs to the AAA ATPase family. (968 aa)
Sros_6737Hypothetical protein; KEGG: abo:ABO_1307 sensor histidine kinase/respose regulator. (181 aa)
Sros_6756ATPase with chaperone activity ATP-binding subunit-like protein; KEGG: bha:BH0103 class III stress response-related ATPase. (250 aa)
Sros_6762Hypothetical protein. (130 aa)
Sros_7100KEGG: met:M446_1988 ATPase central domain- containing protein. (780 aa)
ftsH-2Microtubule-severing ATPase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (663 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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