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ribH ribH Sros_2833 Sros_2833 Sros_2832 Sros_2832 thiE thiE Sros_2783 Sros_2783 Sros_2782 Sros_2782 thiG thiG thiI thiI Sros_2713 Sros_2713 Sros_2651 Sros_2651 cobS cobS panB panB Sros_2313 Sros_2313 Sros_2138 Sros_2138 Sros_2129 Sros_2129 Sros_9368 Sros_9368 Sros_9236 Sros_9236 Sros_9173 Sros_9173 Sros_9171 Sros_9171 Sros_9170 Sros_9170 panC panC panD panD Sros_9019 Sros_9019 kbl kbl Sros_8843 Sros_8843 bioB bioB bioD bioD Sros_8308 Sros_8308 thiL thiL Sros_8003 Sros_8003 Sros_7952 Sros_7952 Sros_7718 Sros_7718 cobD cobD cobQ cobQ cobT cobT Sros_7340 Sros_7340 Sros_6780 Sros_6780 dxs-2 dxs-2 Sros_6709 Sros_6709 Sros_6338 Sros_6338 Sros_6258 Sros_6258 Sros_6184 Sros_6184 pdxS pdxS pdxT pdxT Sros_6055 Sros_6055 Sros_5884 Sros_5884 cobB cobB Sros_5599 Sros_5599 Sros_5598 Sros_5598 cbiD cbiD Sros_5596 Sros_5596 Sros_5595 Sros_5595 Sros_5593 Sros_5593 Sros_5591 Sros_5591 Sros_4900 Sros_4900 Sros_4714 Sros_4714 Sros_4542 Sros_4542 Sros_4177 Sros_4177 Sros_4157 Sros_4157 Sros_3844 Sros_3844 Sros_3773 Sros_3773 dxs dxs Sros_2837 Sros_2837 Sros_0094 Sros_0094 Sros_0123 Sros_0123 Sros_0914 Sros_0914 Sros_0926 Sros_0926 Sros_0993 Sros_0993 serC serC pdxH pdxH Sros_1152 Sros_1152 Sros_1519 Sros_1519 Sros_1620 Sros_1620 Sros_1675 Sros_1675 ribBA ribBA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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ribHRiboflavin synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (156 aa)
Sros_2833KEGG: sus:Acid_4223 riboflavin synthase subunit alpha. (202 aa)
Sros_2832Diaminohydroxyphosphoribosylaminopyrimidinedeami nase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (388 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (213 aa)
Sros_2783KEGG: mex:Mext_0605 glycine oxidase ThiO. (372 aa)
Sros_2782KEGG: har:HEAR0262 putative thiamine biosynthesis protein ThiS. (66 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (252 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (400 aa)
Sros_2713KEGG: hypothetical protein. (227 aa)
Sros_2651Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase-like protein; KEGG: bvi:Bcep1808_2531 adenosylcobinamide kinase. (402 aa)
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (323 aa)
panB3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (281 aa)
Sros_2313KEGG: aca:ACP_1928 sorbitol oxidase. (427 aa)
Sros_2138Putative transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (221 aa)
Sros_2129KEGG: xac:XAC1253 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (317 aa)
Sros_9368KEGG: abo:ABO_0256 7,8-diaminononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (406 aa)
Sros_9236KEGG: cvi:CV_0803 5-aminolevulinate synthase. (400 aa)
Sros_9173Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (283 aa)
Sros_9171Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
Sros_91702-amino-4-hydroxy-6-hydroxymethyldihydropteridin ediphosphokinase; KEGG: pca:Pcar_0250 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (165 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (142 aa)
Sros_9019KEGG: mms:mma_3546 aldo/keto reductase family oxidoreductase. (277 aa)
kblGlycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (390 aa)
Sros_8843Hypothetical protein; KEGG: geo:Geob_0328 glyoxalase/bleomycin resistance protein/dioxygenase. (215 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (332 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (240 aa)
Sros_8308KEGG: mxa:MXAN_1258 8-amino-7-oxononanoate synthase. (389 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (318 aa)
Sros_8003KEGG: sfu:Sfum_1692 phosphomethylpyrimidine kinase. (272 aa)
Sros_7952KEGG: met:M446_1420 2,5-didehydrogluconate reductase. (270 aa)
Sros_7718Putative lyase; KEGG: cti:RALTA_B0885 putative lyase. (136 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (369 aa)
cobQAdenosylcobyric acid synthase (glutamine- hydrolyzing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (509 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazolephos phoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (382 aa)
Sros_7340KEGG: mlo:mlr1197 hypothetical protein. (115 aa)
Sros_6780L-gulonolactone oxidase; KEGG: bur:Bcep18194_B3008 FAD-linked oxidoreductase. (438 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa)
Sros_6709Pyrimidine reductase riboflavin biosynthesis- like protein; KEGG: pst:PSPTO_0690 riboflavin biosynthesis protein RibD. (240 aa)
Sros_6338Putative transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (231 aa)
Sros_6258Hypothetical protein; KEGG: pin:Ping_0445 colicin uptake-like protein. (278 aa)
Sros_6184KEGG: gdj:Gdia_0950 protein of unknown function DUF336. (133 aa)
pdxSSnz1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (304 aa)
pdxTSNO glutamine amidotransferase family; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa)
Sros_6055Uncharacterized membrane-anchored protein-like protein; KEGG: bha:BH2771 hypothetical protein. (403 aa)
Sros_5884Cob(I)yrinic acid a,c-diamide adenosyltransferase; KEGG: bid:Bind_0386 cob(I)alamin adenosyltransferase. (200 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (478 aa)
Sros_5599KEGG: pmy:Pmen_4570 precorrin-6y C5,15- methyltransferase (decarboxylating), CbiE subunit. (407 aa)
Sros_5598KEGG: oan:Oant_1885 precorrin-4 C11- methyltransferase; Belongs to the precorrin methyltransferase family. (247 aa)
cbiDCobalamin biosynthetic protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (357 aa)
Sros_5596KEGG: rru:Rru_A2988 precorrin-6A reductase. (250 aa)
Sros_5595Precorrin-3B methylase-like protein; KEGG: bac:BamMC406_1589 precorrin-3B C17- methyltransferase. (509 aa)
Sros_5593KEGG: bmj:BMULJ_01675 precorrin-8X methylmutase. (208 aa)
Sros_5591Cobaltochelatase; KEGG: pau:PA14_25970 cobaltochelatase. (1207 aa)
Sros_4900KEGG: afw:Anae109_1654 glyoxalase/bleomycin resistance protein/dioxygenase. (156 aa)
Sros_4714Uncharacterized protein putative amidase-like protein; KEGG: scl:sce1994 hypothetical protein. (265 aa)
Sros_4542KEGG: sil:SPO3081 glyoxalase family protein. (145 aa)
Sros_4177Putative transcriptional activator, TenA family; KEGG: ret:RHE_CH00249 TenA family transcription regulator. (222 aa)
Sros_4157KEGG: mno:Mnod_7784 transcriptional activator, TenA family. (222 aa)
Sros_3844Putative transcriptional activator, TenA family; KEGG: mms:mma_0874 TenA family transcription regulator. (228 aa)
Sros_3773Pyridoxal 5'-phosphate synthase; KEGG: rso:RSc0767 pyridoxamine 5'-phosphate oxidase. (216 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (647 aa)
Sros_2837Hypothetical protein. (152 aa)
Sros_0094KEGG: ara:Arad_3055 lactoylglutathione lyase protein. (115 aa)
Sros_0123Putative transcriptional activator, TenA family; KEGG: bha:BH2679 transcriptional regulator of extracellular enzyme genes. (201 aa)
Sros_0914Glutamine amidotransferase-like protein; KEGG: sal:Sala_2756 cobyric acid synthase CobQ. (238 aa)
Sros_0926Uncharacterized protein possibly involved in utilization of glycolate and propanediol-like protein; KEGG: rpt:Rpal_4963 protein of unknown function DUF336. (183 aa)
Sros_0993KEGG: gme:Gmet_2441 cobalamin (vitamin B12) biosynthesis CbiM protein. (344 aa)
serCPhosphoserine aminotransferase-like protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (369 aa)
pdxHPyridoxal 5'-phosphate synthase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (217 aa)
Sros_1152Hypothetical protein; KEGG: gdj:Gdia_0627 Fmu (Sun) domain protein. (388 aa)
Sros_1519KEGG: bcj:BCAS0137 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
Sros_1620KEGG: psa:PST_2854 glyoxalase family protein. (133 aa)
Sros_1675KEGG: mmr:Mmar10_2358 ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (196 aa)
ribBAConserved hypothetical protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (404 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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