STRINGSTRING
Sros_0289 Sros_0289 Sros_0376 Sros_0376 nuoD nuoD Sros_0589 Sros_0589 Sros_0655 Sros_0655 Sros_0924 Sros_0924 Sros_1254 Sros_1254 Sros_1344 Sros_1344 Sros_1689 Sros_1689 Sros_1706 Sros_1706 dapB dapB Sros_2368 Sros_2368 hisD hisD Sros_3534 Sros_3534 Sros_4072 Sros_4072 Sros_4147 Sros_4147 Sros_4316 Sros_4316 Sros_4427 Sros_4427 Sros_4633 Sros_4633 Sros_4950 Sros_4950 Sros_5041 Sros_5041 Sros_5073 Sros_5073 Sros_5363 Sros_5363 Sros_6038 Sros_6038 nadK nadK argC argC Sros_6151 Sros_6151 Sros_6157 Sros_6157 Sros_6488 Sros_6488 Sros_6730 Sros_6730 nadK-2 nadK-2 Sros_7136 Sros_7136 Sros_7152 Sros_7152 Sros_7697 Sros_7697 Sros_7840 Sros_7840 gpsA gpsA Sros_8042 Sros_8042 Sros_8047 Sros_8047 Sros_8061 Sros_8061 Sros_8241 Sros_8241 Sros_8298 Sros_8298 cobB-2 cobB-2 Sros_9114 Sros_9114 nuoD-2 nuoD-2 Sros_9310 Sros_9310
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_0289KEGG: smd:Smed_2232 6-phosphogluconate dehydrogenase NAD-binding. (293 aa)
Sros_0376KEGG: sus:Acid_4597 UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (420 aa)
nuoDNADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (441 aa)
Sros_0589NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (428 aa)
Sros_0655GDP-mannose 6-dehydrogenase; KEGG: mno:Mnod_5882 nucleotide sugar dehydrogenase. (438 aa)
Sros_0924KEGG: baa:BA_2347 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase. (291 aa)
Sros_1254KEGG: oca:OCAR_5440 isocitrate dehydrogenase, NADP- dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
Sros_1344KEGG: swi:Swit_4534 UDP-glucose 6-dehydrogenase. (439 aa)
Sros_1689KEGG: mes:Meso_2948 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (489 aa)
Sros_1706Malate dehydrogenase (oxaloacetate- decarboxylating); KEGG: sat:SYN_00517 NAD-dependent malic enzyme. (470 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (245 aa)
Sros_2368KEGG: swi:Swit_4534 UDP-glucose 6-dehydrogenase. (441 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
Sros_3534KEGG: rlt:Rleg2_4009 D-isomer specific 2- hydroxyacid dehydrogenase NAD-binding. (333 aa)
Sros_4072KEGG: baa:BA_2347 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase. (287 aa)
Sros_4147KEGG: mxa:MXAN_4748 3-hydroxyisobutyrate dehydrogenase family protein. (294 aa)
Sros_4316KEGG: aba:Acid345_2541 glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
Sros_4427KEGG: baa:BA_2347 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase. (294 aa)
Sros_4633KEGG: bha:BH1010 hypothetical protein; Belongs to the WrbA family. (226 aa)
Sros_4950KEGG: baa:BA_2347 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase. (302 aa)
Sros_5041KEGG: sil:SPO2705 3-hydroxyacyl-CoA dehydrogenase family protein. (317 aa)
Sros_5073KEGG: baa:BA_2347 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase. (293 aa)
Sros_5363KEGG: baa:BA_2347 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase. (295 aa)
Sros_6038KEGG: sus:Acid_7375 glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
nadKSugar kinase-like protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (301 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (340 aa)
Sros_61513-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase-like protein; KEGG: ppd:Ppro_2197 2-hydroxy-3-oxopropionate reductase. (402 aa)
Sros_6157KEGG: baa:BA_2347 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase. (288 aa)
Sros_6488KEGG: mxa:MXAN_2689 lipopolysaccharide biosynthesis protein; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (419 aa)
Sros_6730KEGG: sfu:Sfum_1404 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (690 aa)
nadK-2ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (285 aa)
Sros_7136KEGG: mno:Mnod_1061 6-phosphogluconate dehydrogenase NAD-binding. (321 aa)
Sros_7152KEGG: bpt:Bpet0409 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
Sros_7697KEGG: asa:ASA_2413 ATP-NAD/AcoX kinase. (408 aa)
Sros_7840KEGG: aca:ACP_2332 D-isomer specific 2-hydroxyacid dehydrogenase family protein. (321 aa)
gpsAKEGG: ade:Adeh_0396 glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (336 aa)
Sros_8042KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. (348 aa)
Sros_8047KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
Sros_8061KEGG: aca:ACP_2332 D-isomer specific 2-hydroxyacid dehydrogenase family protein. (302 aa)
Sros_8241KEGG: acr:Acry_2572 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (346 aa)
Sros_8298KEGG: bha:BH3168 malic enzyme (malate dehydrogenase). (397 aa)
cobB-2Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (293 aa)
Sros_9114Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (325 aa)
nuoD-2NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (398 aa)
Sros_9310KEGG: pca:Pcar_1903 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (355 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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