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| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (563 aa) |
| | Sros_2998 | Prephenate dehydrogenase-like protein; KEGG: bpt:Bpet1887 hypothetical protein. (357 aa) |
| | Sros_3051 | KEGG: plu:plu1439 hypothetical protein. (257 aa) |
| | Sros_3052 | KEGG: vei:Veis_4212 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (584 aa) |
| | Sros_3097 | KEGG: baa:BA_0116 proline dehydrogenase. (308 aa) |
| | Sros_3160 | Peptidase M20; KEGG: dal:Dalk_4445 peptidase M20. (421 aa) |
| | Sros_3264 | KEGG: dac:Daci_3022 deaminase-reductase domain- containing protein. (180 aa) |
| | Sros_3332 | KEGG: bha:BH1939 proline dehydrogenase. (323 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (626 aa) |
| | Sros_3418 | KEGG: dal:Dalk_0154 pyridoxal-dependent decarboxylase. (472 aa) |
| | Sros_3505 | KEGG: btr:Btr_1447 hypothetical protein. (371 aa) |
| | Sros_3531 | KEGG: mes:Meso_2469 asparagine synthase (glutamine- hydrolyzing). (596 aa) |
| | Sros_3534 | KEGG: rlt:Rleg2_4009 D-isomer specific 2- hydroxyacid dehydrogenase NAD-binding. (333 aa) |
| | trpF | KEGG: sil:SPO0806 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (211 aa) |
| | Sros_3604 | Peptidase M20; KEGG: dal:Dalk_4445 peptidase M20. (434 aa) |
| | Sros_3644 | KEGG: mlo:mlr0926 hypothetical protein. (190 aa) |
| | Sros_3665 | KEGG: bsu:BSU37740 hypothetical protein. (187 aa) |
| | Sros_3696 | KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (181 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (354 aa) |
| | Sros_3752 | KEGG: bbt:BBta_0633 putative cysteine synthase (O- acetylserine sulfhydrylase) (O-acetylserine (thiol)-lyase) (CSase). (351 aa) |
| | Sros_3753 | KEGG: hch:HCH_03695 diaminopimelate decarboxylase. (432 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (579 aa) |
| | Sros_3848 | KEGG: scl:sce1370 dihydrofolate reductase family protein. (190 aa) |
| | Sros_3859 | KEGG: bvi:Bcep1808_7299 sarcosine oxidase, gamma subunit. (190 aa) |
| | Sros_3889 | KEGG: swi:Swit_1410 GCN5-related N- acetyltransferase. (131 aa) |
| | Sros_3925 | KEGG: sil:SPO3529 serine hydroxymethyltransferase. (417 aa) |
| | arcA-2 | KEGG: oan:Oant_4646 arginine deiminase. (419 aa) |
| | Sros_3991 | KEGG: mlo:mll8760 hypothetical protein. (229 aa) |
| | gcvP | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (951 aa) |
| | Sros_4096 | KEGG: mxa:MXAN_1250 RibD domain protein. (192 aa) |
| | Sros_4119 | KEGG: aca:ACP_1470 threonine dehydratase catabolic. (319 aa) |
| | Sros_4169 | Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (619 aa) |
| | Sros_4224 | KEGG: mlo:mlr2503 hypothetical protein. (178 aa) |
| | Sros_4248 | KEGG: swi:Swit_2076 dihydrodipicolinate reductase. (359 aa) |
| | Sros_4372 | KEGG: mrd:Mrad2831_1541 pyridoxal-5'-phosphate- dependent protein beta subunit. (392 aa) |
| | Sros_4493 | Bifunctional deaminase-reductase-like protein; KEGG: rfr:Rfer_2843 bifunctional deaminase- reductase-like. (214 aa) |
| | Sros_4529 | CTP synthase; KEGG: ent:Ent638_1664 hypothetical protein. (251 aa) |
| | Sros_4565 | KEGG: bur:Bcep18194_B1493 serine/threonine dehydratase. (320 aa) |
| | Sros_4607 | Putative homoserine kinase type II (protein kinase fold)-like protein; KEGG: eli:ELI_14350 tyrosine protein kinase:aminoglycoside phosphotransferase. (294 aa) |
| | Sros_4799 | Hypothetical protein; KEGG: kpn:KPN_02962 putative bifunctional deaminase- reductase. (89 aa) |
| | Sros_4905 | Amidohydrolase; KEGG: sus:Acid_6576 amidohydrolase. (381 aa) |
| | trpB-2 | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa) |
| | trpA-2 | Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa) |
| | Sros_4971 | Cysteine synthase-like protein; KEGG: mlo:mlr9541 cysteine synthase. (379 aa) |
| | Sros_5047 | KEGG: swi:Swit_3093 hypothetical protein. (308 aa) |
| | Sros_5063 | Amidohydrolase; KEGG: sus:Acid_6576 amidohydrolase. (381 aa) |
| | Sros_5138 | GMP synthase - Glutamine amidotransferase domain- like protein; KEGG: gbm:Gbem_1504 glutamine amidotransferase class-I. (238 aa) |
| | Sros_5171 | KEGG: ret:RHE_PF00444 hypothetical protein. (594 aa) |
| | Sros_5213 | KEGG: rec:RHECIAT_PC0000475 putative aminoglycoside phosphotransferase protein (antibiotic resistance protein). (279 aa) |
| | Sros_5254 | Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (597 aa) |
| | Sros_5324 | KEGG: rle:pRL80036 hypothetical protein. (318 aa) |
| | Sros_5415 | KEGG: geo:Geob_0282 alcohol dehydrogenase GroES domain protein. (393 aa) |
| | Sros_5431 | Hypothetical protein; KEGG: bpt:Bpet4090 acetyltransferase. (173 aa) |
| | Sros_5539 | KEGG: bmn:BMA10247_1403 hypothetical protein. (363 aa) |
| | Sros_5566 | KEGG: sus:Acid_1483 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (612 aa) |
| | lysA-2 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (451 aa) |
| | Sros_5592 | Sulfite reductase beta subunit (hemoprotein)- like protein; KEGG: pae:PA2906 putative oxidoreductase. (473 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (302 aa) |
| | Sros_5654 | Hypothetical protein; KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (122 aa) |
| | Sros_5703 | Peptidase M20; KEGG: aba:Acid345_0237 peptidase M20. (405 aa) |
| | arcA-3 | KEGG: oan:Oant_4646 arginine deiminase. (434 aa) |
| | Sros_5832 | KEGG: sus:Acid_6255 deaminase-reductase domain- containing protein. (187 aa) |
| | cobB | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (478 aa) |
| | Sros_5917 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1154 aa) |
| | Sros_5957 | KEGG: kpe:KPK_4258 hypothetical protein. (206 aa) |
| | argH | KEGG: pfo:Pfl01_2852 argininosuccinate lyase. (472 aa) |
| | argG | KEGG: bha:BH3187 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa) |
| | argR | Arginine repressor; Regulates arginine biosynthesis genes. (167 aa) |
| | Sros_6073 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (338 aa) |
| | argD | KEGG: afw:Anae109_2686 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (322 aa) |
| | argJ | Amino-acid N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (384 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (340 aa) |
| | pdxT | SNO glutamine amidotransferase family; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa) |
| | dapD | Putative tetrahydrodipicolinate N- succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (325 aa) |
| | hutH | Histidine ammonia-lyase; KEGG: scl:sce6082 hypothetical protein. (515 aa) |
| | Sros_6183 | KEGG: mlo:mlr6716 hypothetical protein. (346 aa) |
| | kynA | Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (294 aa) |
| | glmS-2 | Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (606 aa) |
| | Sros_4921 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa) |
| | Sros_1779 | KEGG: bbr:BB2432 allantoate amidohydrolase. (387 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (551 aa) |
| | Sros_1760 | Glutamate--ammonia ligase; KEGG: acr:Acry_2393 glutamine synthetase, catalytic region. (447 aa) |
| | Sros_1757 | Peptidase C26; KEGG: afw:Anae109_0076 peptidase C26. (231 aa) |
| | gcvT | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (362 aa) |
| | gcvH | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | Sros_1751 | KEGG: bur:Bcep18194_B3007 amino acid aldolase or racemase-like. (397 aa) |
| | Sros_1728 | KEGG: eba:ebA896 cysteine synthase B. (315 aa) |
| | Sros_1727 | Molybdopterin synthase subunit MoaD; KEGG: scl:sce5755 hypothetical protein. (92 aa) |
| | Sros_1725 | Mov34/MPN/PAD-1; KEGG: nmu:Nmul_A0971 Mov34/MPN/PAD-1. (138 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (336 aa) |
| | Sros_1649 | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa) |
| | Sros_1638 | KEGG: gme:Gmet_1629 homoserine dehydrogenase. (430 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (460 aa) |
| | Sros_1634 | Hypothetical protein; KEGG: acp:A2cp1_2970 asparagine synthase. (552 aa) |
| | Sros_1553 | KEGG: bpl:BURPS1106A_0672 hypothetical protein. (369 aa) |
| | Sros_1520 | KEGG: vha:VIBHAR_01795 alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa) |
| | Sros_1518 | Peptidase M20; KEGG: ade:Adeh_0863 peptidase M20. (448 aa) |
| | Sros_1449 | KEGG: tmz:Tmz1t_1660 NAD-glutamate dehydrogenase. (1625 aa) |
| | Sros_1425 | KEGG: sus:Acid_1598 glutamine--fructose-6-phosphate transaminase (isomerizing). (344 aa) |
| | Sros_1268 | Aminoacylase; KEGG: bsu:BSU29290 hypothetical protein. (412 aa) |
| | folD-2 | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa) |
| | guaA | GMP synthase C terminal domain protein; Catalyzes the synthesis of GMP from XMP. (523 aa) |
| | Sros_1141 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (371 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (614 aa) |
| | Sros_1023 | Bifunctional deaminase-reductase-like protein; KEGG: mes:Meso_2196 bifunctional deaminase- reductase-like. (178 aa) |
| | serC | Phosphoserine aminotransferase-like protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (369 aa) |
| | dtd | D-tyrosyl-tRNA deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (141 aa) |
| | Sros_0914 | Glutamine amidotransferase-like protein; KEGG: sal:Sala_2756 cobyric acid synthase CobQ. (238 aa) |
| | Sros_0902 | KEGG: cja:CJA_2345 rhodanese-like domain protein. (279 aa) |
| | Sros_0841 | KEGG: scl:sce6636 hypothetical protein. (189 aa) |
| | Sros_0724 | KEGG: scl:sce1370 dihydrofolate reductase family protein. (197 aa) |
| | Sros_0542 | Phosphoserine phosphatase-like protein; KEGG: afw:Anae109_1214 HAD family hydrolase. (289 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa) |
| | Sros_0500 | Phosphoserine phosphatase; KEGG: scl:sce0663 hypothetical protein. (407 aa) |
| | Sros_0440 | Diaminopimelate decarboxylase-like protein; KEGG: bar:GBAA1438 diaminopimelate decarboxylase. (276 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (279 aa) |
| | Sros_0337 | L-asparaginase; KEGG: scl:sce3372 L-asparaginase. (322 aa) |
| | egtC | Conserved hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. (234 aa) |
| | egtD | Conserved hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (326 aa) |
| | Sros_0327 | Succinyl-diaminopimelate desuccinylase; KEGG: dde:Dde_1186 M20/M25/M40 family peptidase. (434 aa) |
| | serS | Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (420 aa) |
| | pheA | KEGG: ade:Adeh_1779 prephenate dehydratase. (306 aa) |
| | Sros_0110 | KEGG: gbe:GbCGDNIH1_0821 anthranilate synthase component II. (190 aa) |
| | Sros_0061 | Homoserine O-acetyltransferase; KEGG: bra:BRADO5867 hypothetical protein; Belongs to the AB hydrolase superfamily. MetX family. (338 aa) |
| | Sros_0003 | KEGG: mlo:mll1845 hypothetical protein. (243 aa) |
| | Sros_6500 | KEGG: gbm:Gbem_1778 asparagine synthase (glutamine- hydrolyzing). (638 aa) |
| | Sros_6542 | KEGG: sat:SYN_01213 carbamate kinase; Belongs to the carbamate kinase family. (314 aa) |
| | Sros_6569 | KEGG: mxa:MXAN_3751 aminotransferase, classes I and II. (394 aa) |
| | Sros_6632 | KEGG: sus:Acid_3591 cyclase family protein. (265 aa) |
| | glyA-2 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa) |
| | Sros_6725 | KEGG: mlo:mll3044 hypothetical protein. (376 aa) |
| | Sros_6748 | KEGG: hypothetical protein. (168 aa) |
| | Sros_6820 | Peptidase M20; KEGG: aba:Acid345_0237 peptidase M20. (412 aa) |
| | kynA-2 | Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (264 aa) |
| | Sros_6950 | Kynureninase; KEGG: ade:Adeh_3164 kynureninase. (403 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (268 aa) |
| | Sros_2190 | KEGG: rec:RHECIAT_PB0000363 hypothetical protein. (226 aa) |
| | Sros_2137 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1245 aa) |
| | Sros_2136 | KEGG: pla:Plav_3174 GCN5-related N- acetyltransferase. (169 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (245 aa) |
| | Sros_2040 | Glutamate--ammonia ligase; KEGG: hypothetical protein; K01915 glutamine synthetase. (337 aa) |
| | Sros_2030 | Hypothetical protein; KEGG: vei:Veis_2871 aminoglycoside phosphotransferase. (285 aa) |
| | Sros_1999 | KEGG: swi:Swit_2102 cyclase family protein. (307 aa) |
| | hutI | KEGG: dps:DP2351 imidazolonepropionase. (382 aa) |
| | Sros_6952 | KEGG: abc:ACICU_01927 dihydrofolate reductase. (178 aa) |
| | Sros_6982 | KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (183 aa) |
| | Sros_6984 | KEGG: bpt:Bpet1887 hypothetical protein. (283 aa) |
| | trpD-2 | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (352 aa) |
| | Sros_7064 | KEGG: scl:sce6912 thiosulfate sulfurtransferase. (270 aa) |
| | Sros_7078 | KEGG: hch:HCH_00228 histone acetyltransferase HPA2- like acetyltransferase. (201 aa) |
| | Sros_7152 | KEGG: bpt:Bpet0409 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa) |
| | Sros_7185 | KEGG: mxa:MXAN_1250 RibD domain protein. (190 aa) |
| | Sros_7196 | KEGG: apa:APP7_1355 putative sulfate transport protein CysZ. (249 aa) |
| | Sros_7214 | KEGG: swi:Swit_3995 hypothetical protein. (589 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate--homocyste ineS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (738 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (429 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (374 aa) |
| | ilvD | KEGG: nmn:NMCC_1068 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (612 aa) |
| | cobQ | Adenosylcobyric acid synthase (glutamine- hydrolyzing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (509 aa) |
| | Sros_7402 | Hypothetical protein; KEGG: sme:SM_b20505 putative trifolitoxin immunity protein. (266 aa) |
| | Sros_7497 | Glutamate--ammonia ligase; KEGG: rce:RC1_1466 gamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family. (445 aa) |
| | Sros_7501 | KEGG: afr:AFE_2528 glutamine amidotransferase, class I. (230 aa) |
| | Sros_7561 | Nucleoside phosphorylase-like protein; KEGG: bja:blr0077 hypothetical protein. (296 aa) |
| | Sros_7584 | KEGG: pmy:Pmen_4335 rhodanese domain-containing protein. (283 aa) |
| | Sros_7680 | Hippurate hydrolase; KEGG: sal:Sala_2314 peptidase M20D, amidohydrolase. (399 aa) |
| | Sros_7698 | KEGG: vei:Veis_2458 glycine dehydrogenase subunit 2. (519 aa) |
| | Sros_7699 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (443 aa) |
| | Sros_7849 | Aminoacylase; KEGG: dvl:Dvul_0678 amidohydrolase. (419 aa) |
| | Sros_7851 | KEGG: oan:Oant_4491 glutamine synthetase catalytic region. (439 aa) |
| | Sros_7858 | Hypothetical protein; KEGG: ppg:PputGB1_3631 deaminase-reductase domain- containing protein. (199 aa) |
| | Sros_7919 | KEGG: acp:A2cp1_2116 histidine ammonia-lyase. (491 aa) |
| | Sros_7984 | KEGG: dac:Daci_5156 pyridoxal-5'-phosphate- dependent protein beta subunit. (358 aa) |
| | Sros_8009 | KEGG: sfu:Sfum_2670 cystathionine gamma-synthase. (406 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (195 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (459 aa) |
| | Sros_8038 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (525 aa) |
| | Sros_8041 | KEGG: nar:Saro_2671 branched-chain amino acid aminotransferase. (364 aa) |
| | Sros_2587 | Cystathionine gamma-synthase; KEGG: cko:CKO_04984 hypothetical protein. (390 aa) |
| | Sros_8042 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. (348 aa) |
| | Sros_8047 | KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa) |
| | Sros_8058 | KEGG: gur:Gura_3719 acetolactate synthase 3 regulatory subunit. (174 aa) |
| | Sros_8059 | KEGG: ade:Adeh_1978 acetolactate synthase, large subunit. (578 aa) |
| | Sros_8078 | KEGG: mxa:MXAN_1973 hypothetical protein. (334 aa) |
| | Sros_8241 | KEGG: acr:Acry_2572 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (346 aa) |
| | Sros_8265 | KEGG: swi:Swit_2076 dihydrodipicolinate reductase. (352 aa) |
| | Sros_8313 | KEGG: scl:sce8127 putative acetolactate synthase; Belongs to the TPP enzyme family. (550 aa) |
| | Sros_8366 | KEGG: pol:Bpro_4782 Orn/DAP/Arg decarboxylase 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (392 aa) |
| | Sros_8385 | KEGG: hch:HCH_02851 molybdopterin/thiamine biosynthesis family protein. (393 aa) |
| | Sros_8429 | Dipeptidase; KEGG: scl:sce2952 dipeptidase. (353 aa) |
| | Sros_8431 | KEGG: bba:Bd1775 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (276 aa) |
| | Sros_8547 | KEGG: gme:Gmet_3072 threonine dehydratase. (402 aa) |
| | Sros_8563 | KEGG: afw:Anae109_3845 cystathionine gamma-lyase. (379 aa) |
| | Sros_8566 | KEGG: scl:sce0438 cystathionine beta-synthase. (456 aa) |
| | Sros_8654 | Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (269 aa) |
| | Sros_8776 | MetE; KEGG: dat:HRM2_34760 MetE. (367 aa) |
| | Sros_8818 | D-aspartate oxidase; KEGG: hypothetical protein. (371 aa) |
| | Sros_8845 | KEGG: bar:GBAA0242 homogentisate 1,2-dioxygenase, putative. (389 aa) |
| | Sros_8912 | Molybdopterin synthase subunit MoaD; KEGG: scl:sce5755 hypothetical protein. (91 aa) |
| | Sros_8913 | KEGG: aca:ACP_3389 threonine synthase. (429 aa) |
| | Sros_8940 | L-lysine 2,3-aminomutase; KEGG: mxa:MXAN_6263 hypothetical protein. (461 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (227 aa) |
| | Sros_8985 | 5 10-methylenetetrahydrofolate reductase-like protein; KEGG: gur:Gura_1171 methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (259 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (478 aa) |
| | Sros_8995 | KEGG: bsu:BSU24080 leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (367 aa) |
| | Sros_9103 | KEGG: msl:Msil_2816 thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (577 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (407 aa) |
| | Sros_9151 | N-acetylglutamate synthase and related acetyltransferase-like protein; KEGG: pca:Pcar_2325 acetyltransferase; Belongs to the acetyltransferase family. (195 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (142 aa) |
| | Sros_9200 | KEGG: gsu:GSU0562 hypothetical protein. (183 aa) |
| | Sros_9227 | Peptidase M20; KEGG: dal:Dalk_4445 peptidase M20. (435 aa) |
| | Sros_9259 | KEGG: bur:Bcep18194_C7217 GCN5-related N- acetyltransferase. (170 aa) |
| | Sros_9310 | KEGG: pca:Pcar_1903 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (355 aa) |
| | Sros_9311 | Aspartate kinase; KEGG: dat:HRM2_35870 LysC; Belongs to the aspartokinase family. (424 aa) |
| | argG-2 | KEGG: lch:Lcho_0912 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (482 aa) |
| | Sros_2580 | KEGG: aba:Acid345_1511 putative cyclase. (219 aa) |
| | Sros_2565 | KEGG: pde:Pden_1729 alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa) |
| | Sros_2553 | KEGG: btr:Btr_1447 hypothetical protein. (688 aa) |
| | Sros_2502 | KEGG: csa:Csal_0030 acetylornithine deacetylase. (418 aa) |
| | Sros_2367 | Dihydrodipicolinate synthase/N-acetylneuraminate lyase-like protein; KEGG: acp:A2cp1_4217 dihydrodipicolinate synthase. (333 aa) |
| | Sros_2361 | KEGG: bja:bll4205 hypothetical protein; Belongs to the DapA family. (351 aa) |
| | Sros_2331 | Amidinotransferase; KEGG: aeh:Mlg_0130 amidinotransferase. (264 aa) |
| | Sros_2330 | KEGG: rle:RL4385 ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (403 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (569 aa) |
| | Sros_2271 | KEGG: ect:ECIAI39_0691 imidazolonepropionase (imidazolone-5-propionate hydrolase); Belongs to the metallo-dependent hydrolases superfamily. HutI family. (402 aa) |
| | Sros_2589 | KEGG: mlo:mlr3510 threonine dehydratase. (303 aa) |
| | Sros_2611 | KEGG: sat:SYN_01628 glutamine synthetase. (453 aa) |
| | Sros_2617 | KEGG: gbm:Gbem_1504 glutamine amidotransferase class-I. (233 aa) |
| | Sros_2629 | KEGG: dal:Dalk_5100 glutamine synthetase, type I. (474 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa) |
| | Sros_2740 | KEGG: bsu:BSU02410 homocysteine methyltransferase. (287 aa) |
| | Sros_2788 | KEGG: afw:Anae109_2667 5,10- methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (310 aa) |
| | Sros_2798 | KEGG: apl:APL_1318 carbamate kinase; Belongs to the carbamate kinase family. (311 aa) |
| | Sros_2799 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa) |
| | arcA | Arginine deiminase; KEGG: ecq:ECED1_5105 putative arginine deiminase (arginine dihydrolase). (414 aa) |
| | carA | Carbamoyl-phosphate synthase (glutamine- hydrolyzing); KEGG: hch:HCH_01227 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (400 aa) |
| | carB | KEGG: geo:Geob_3271 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1097 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (209 aa) |
| | hisA | Phosphoribosylanthranilate isomerase; KEGG: plu:plu0797 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase. (240 aa) |
| | Sros_2916 | KEGG: glutamate-ammonia ligase; Belongs to the glutamine synthetase family. (469 aa) |
| | trpC | KEGG: afw:Anae109_0373 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (269 aa) |
| | trpB | Tryptophan synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa) |
| | Sros_2949 | KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin). (1501 aa) |
| | Sros_2950 | KEGG: aba:Acid345_3679 glutamate synthase (NADH) small subunit. (492 aa) |
