STRINGSTRING
Sros_6982 Sros_6982 Sros_3752 Sros_3752 Sros_3753 Sros_3753 leuA-2 leuA-2 Sros_3848 Sros_3848 Sros_3889 Sros_3889 Sros_3925 Sros_3925 Sros_4096 Sros_4096 Sros_4119 Sros_4119 Sros_4169 Sros_4169 Sros_4224 Sros_4224 Sros_4248 Sros_4248 Sros_4372 Sros_4372 Sros_4493 Sros_4493 Sros_4565 Sros_4565 Sros_4607 Sros_4607 Sros_4799 Sros_4799 Sros_4921 Sros_4921 trpB-2 trpB-2 trpA-2 trpA-2 Sros_4971 Sros_4971 Sros_5171 Sros_5171 Sros_5213 Sros_5213 Sros_5254 Sros_5254 Sros_5431 Sros_5431 Sros_5539 Sros_5539 Sros_5566 Sros_5566 lysA-2 lysA-2 Sros_5592 Sros_5592 ilvE ilvE Sros_5654 Sros_5654 Sros_5703 Sros_5703 Sros_5832 Sros_5832 Sros_5917 Sros_5917 Sros_5957 Sros_5957 argH argH argG argG argR argR Sros_6073 Sros_6073 argD argD argB argB argJ argJ argC argC dapD dapD Sros_6183 Sros_6183 Sros_6500 Sros_6500 glyA-2 glyA-2 Sros_6725 Sros_6725 Sros_6748 Sros_6748 Sros_6820 Sros_6820 Sros_6952 Sros_6952 selD selD Sros_6984 Sros_6984 trpD-2 trpD-2 Sros_7152 Sros_7152 Sros_7185 Sros_7185 Sros_7196 Sros_7196 Sros_7214 Sros_7214 metE metE proA proA proB proB ilvD ilvD Sros_7402 Sros_7402 Sros_7497 Sros_7497 Sros_7561 Sros_7561 Sros_7680 Sros_7680 Sros_7849 Sros_7849 Sros_7851 Sros_7851 Sros_7858 Sros_7858 Sros_7984 Sros_7984 Sros_8009 Sros_8009 leuD leuD leuC leuC Sros_8038 Sros_8038 Sros_8041 Sros_8041 Sros_8042 Sros_8042 Sros_8047 Sros_8047 ilvC ilvC Sros_8058 Sros_8058 Sros_8059 Sros_8059 Sros_8078 Sros_8078 Sros_8241 Sros_8241 Sros_8265 Sros_8265 Sros_8313 Sros_8313 Sros_8366 Sros_8366 Sros_8385 Sros_8385 Sros_8429 Sros_8429 Sros_8431 Sros_8431 Sros_8547 Sros_8547 Sros_8563 Sros_8563 Sros_8566 Sros_8566 Sros_8654 Sros_8654 Sros_8776 Sros_8776 Sros_8912 Sros_8912 Sros_8913 Sros_8913 Sros_9103 Sros_9103 Sros_9151 Sros_9151 panD panD Sros_9200 Sros_9200 Sros_9227 Sros_9227 Sros_9259 Sros_9259 Sros_9310 Sros_9310 Sros_9311 Sros_9311 argG-2 argG-2 Sros_0061 Sros_0061 pheA pheA serS serS Sros_0327 Sros_0327 egtD egtD folD folD Sros_0440 Sros_0440 Sros_0500 Sros_0500 proC proC Sros_0542 Sros_0542 Sros_0724 Sros_0724 Sros_0841 Sros_0841 serC serC Sros_1023 Sros_1023 Sros_1141 Sros_1141 folD-2 folD-2 Sros_1268 Sros_1268 Sros_1518 Sros_1518 Sros_1634 Sros_1634 lysA lysA Sros_1638 Sros_1638 Sros_1649 Sros_1649 thrB thrB glyA glyA Sros_1725 Sros_1725 Sros_1727 Sros_1727 Sros_1728 Sros_1728 Sros_1760 Sros_1760 Sros_1779 Sros_1779 Sros_2030 Sros_2030 Sros_2040 Sros_2040 dapB dapB Sros_2136 Sros_2136 Sros_2137 Sros_2137 dapF dapF leuA leuA Sros_2330 Sros_2330 Sros_2361 Sros_2361 Sros_2367 Sros_2367 Sros_2502 Sros_2502 Sros_2587 Sros_2587 Sros_2589 Sros_2589 Sros_2611 Sros_2611 Sros_2629 Sros_2629 trpD trpD Sros_2740 Sros_2740 Sros_2788 Sros_2788 Sros_2799 Sros_2799 carA carA carB carB hisA hisA Sros_2916 Sros_2916 trpC trpC trpB trpB trpA trpA Sros_2949 Sros_2949 Sros_2950 Sros_2950 Sros_2998 Sros_2998 Sros_3052 Sros_3052 Sros_3160 Sros_3160 Sros_3264 Sros_3264 edd edd Sros_3531 Sros_3531 Sros_3534 Sros_3534 trpF trpF Sros_3604 Sros_3604 Sros_3644 Sros_3644 Sros_3665 Sros_3665 Sros_3696 Sros_3696
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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Sros_6982KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (183 aa)
Sros_3752KEGG: bbt:BBta_0633 putative cysteine synthase (O- acetylserine sulfhydrylase) (O-acetylserine (thiol)-lyase) (CSase). (351 aa)
Sros_3753KEGG: hch:HCH_03695 diaminopimelate decarboxylase. (432 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (579 aa)
Sros_3848KEGG: scl:sce1370 dihydrofolate reductase family protein. (190 aa)
Sros_3889KEGG: swi:Swit_1410 GCN5-related N- acetyltransferase. (131 aa)
Sros_3925KEGG: sil:SPO3529 serine hydroxymethyltransferase. (417 aa)
Sros_4096KEGG: mxa:MXAN_1250 RibD domain protein. (192 aa)
Sros_4119KEGG: aca:ACP_1470 threonine dehydratase catabolic. (319 aa)
Sros_4169Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (619 aa)
Sros_4224KEGG: mlo:mlr2503 hypothetical protein. (178 aa)
Sros_4248KEGG: swi:Swit_2076 dihydrodipicolinate reductase. (359 aa)
Sros_4372KEGG: mrd:Mrad2831_1541 pyridoxal-5'-phosphate- dependent protein beta subunit. (392 aa)
Sros_4493Bifunctional deaminase-reductase-like protein; KEGG: rfr:Rfer_2843 bifunctional deaminase- reductase-like. (214 aa)
Sros_4565KEGG: bur:Bcep18194_B1493 serine/threonine dehydratase. (320 aa)
Sros_4607Putative homoserine kinase type II (protein kinase fold)-like protein; KEGG: eli:ELI_14350 tyrosine protein kinase:aminoglycoside phosphotransferase. (294 aa)
Sros_4799Hypothetical protein; KEGG: kpn:KPN_02962 putative bifunctional deaminase- reductase. (89 aa)
Sros_4921Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (167 aa)
trpB-2Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
trpA-2Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa)
Sros_4971Cysteine synthase-like protein; KEGG: mlo:mlr9541 cysteine synthase. (379 aa)
Sros_5171KEGG: ret:RHE_PF00444 hypothetical protein. (594 aa)
Sros_5213KEGG: rec:RHECIAT_PC0000475 putative aminoglycoside phosphotransferase protein (antibiotic resistance protein). (279 aa)
Sros_5254Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (597 aa)
Sros_5431Hypothetical protein; KEGG: bpt:Bpet4090 acetyltransferase. (173 aa)
Sros_5539KEGG: bmn:BMA10247_1403 hypothetical protein. (363 aa)
Sros_5566KEGG: sus:Acid_1483 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (612 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (451 aa)
Sros_5592Sulfite reductase beta subunit (hemoprotein)- like protein; KEGG: pae:PA2906 putative oxidoreductase. (473 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (302 aa)
Sros_5654Hypothetical protein; KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (122 aa)
Sros_5703Peptidase M20; KEGG: aba:Acid345_0237 peptidase M20. (405 aa)
Sros_5832KEGG: sus:Acid_6255 deaminase-reductase domain- containing protein. (187 aa)
Sros_5917Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1154 aa)
Sros_5957KEGG: kpe:KPK_4258 hypothetical protein. (206 aa)
argHKEGG: pfo:Pfl01_2852 argininosuccinate lyase. (472 aa)
argGKEGG: bha:BH3187 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (167 aa)
Sros_6073Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (338 aa)
argDKEGG: afw:Anae109_2686 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (322 aa)
argJAmino-acid N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (384 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (340 aa)
dapDPutative tetrahydrodipicolinate N- succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (325 aa)
Sros_6183KEGG: mlo:mlr6716 hypothetical protein. (346 aa)
Sros_6500KEGG: gbm:Gbem_1778 asparagine synthase (glutamine- hydrolyzing). (638 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
Sros_6725KEGG: mlo:mll3044 hypothetical protein. (376 aa)
Sros_6748KEGG: hypothetical protein. (168 aa)
Sros_6820Peptidase M20; KEGG: aba:Acid345_0237 peptidase M20. (412 aa)
Sros_6952KEGG: abc:ACICU_01927 dihydrofolate reductase. (178 aa)
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (354 aa)
Sros_6984KEGG: bpt:Bpet1887 hypothetical protein. (283 aa)
trpD-2Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (352 aa)
Sros_7152KEGG: bpt:Bpet0409 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
Sros_7185KEGG: mxa:MXAN_1250 RibD domain protein. (190 aa)
Sros_7196KEGG: apa:APP7_1355 putative sulfate transport protein CysZ. (249 aa)
Sros_7214KEGG: swi:Swit_3995 hypothetical protein. (589 aa)
metE5-methyltetrahydropteroyltriglutamate--homocyste ineS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (738 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (429 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (374 aa)
ilvDKEGG: nmn:NMCC_1068 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (612 aa)
Sros_7402Hypothetical protein; KEGG: sme:SM_b20505 putative trifolitoxin immunity protein. (266 aa)
Sros_7497Glutamate--ammonia ligase; KEGG: rce:RC1_1466 gamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family. (445 aa)
Sros_7561Nucleoside phosphorylase-like protein; KEGG: bja:blr0077 hypothetical protein. (296 aa)
Sros_7680Hippurate hydrolase; KEGG: sal:Sala_2314 peptidase M20D, amidohydrolase. (399 aa)
Sros_7849Aminoacylase; KEGG: dvl:Dvul_0678 amidohydrolase. (419 aa)
Sros_7851KEGG: oan:Oant_4491 glutamine synthetase catalytic region. (439 aa)
Sros_7858Hypothetical protein; KEGG: ppg:PputGB1_3631 deaminase-reductase domain- containing protein. (199 aa)
Sros_7984KEGG: dac:Daci_5156 pyridoxal-5'-phosphate- dependent protein beta subunit. (358 aa)
Sros_8009KEGG: sfu:Sfum_2670 cystathionine gamma-synthase. (406 aa)
leuDIsopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (195 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (459 aa)
Sros_8038KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (525 aa)
Sros_8041KEGG: nar:Saro_2671 branched-chain amino acid aminotransferase. (364 aa)
Sros_8042KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. (348 aa)
Sros_8047KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa)
Sros_8058KEGG: gur:Gura_3719 acetolactate synthase 3 regulatory subunit. (174 aa)
Sros_8059KEGG: ade:Adeh_1978 acetolactate synthase, large subunit. (578 aa)
Sros_8078KEGG: mxa:MXAN_1973 hypothetical protein. (334 aa)
Sros_8241KEGG: acr:Acry_2572 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (346 aa)
Sros_8265KEGG: swi:Swit_2076 dihydrodipicolinate reductase. (352 aa)
Sros_8313KEGG: scl:sce8127 putative acetolactate synthase; Belongs to the TPP enzyme family. (550 aa)
Sros_8366KEGG: pol:Bpro_4782 Orn/DAP/Arg decarboxylase 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (392 aa)
Sros_8385KEGG: hch:HCH_02851 molybdopterin/thiamine biosynthesis family protein. (393 aa)
Sros_8429Dipeptidase; KEGG: scl:sce2952 dipeptidase. (353 aa)
Sros_8431KEGG: bba:Bd1775 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (276 aa)
Sros_8547KEGG: gme:Gmet_3072 threonine dehydratase. (402 aa)
Sros_8563KEGG: afw:Anae109_3845 cystathionine gamma-lyase. (379 aa)
Sros_8566KEGG: scl:sce0438 cystathionine beta-synthase. (456 aa)
Sros_8654Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (269 aa)
Sros_8776MetE; KEGG: dat:HRM2_34760 MetE. (367 aa)
Sros_8912Molybdopterin synthase subunit MoaD; KEGG: scl:sce5755 hypothetical protein. (91 aa)
Sros_8913KEGG: aca:ACP_3389 threonine synthase. (429 aa)
Sros_9103KEGG: msl:Msil_2816 thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (577 aa)
Sros_9151N-acetylglutamate synthase and related acetyltransferase-like protein; KEGG: pca:Pcar_2325 acetyltransferase; Belongs to the acetyltransferase family. (195 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (142 aa)
Sros_9200KEGG: gsu:GSU0562 hypothetical protein. (183 aa)
Sros_9227Peptidase M20; KEGG: dal:Dalk_4445 peptidase M20. (435 aa)
Sros_9259KEGG: bur:Bcep18194_C7217 GCN5-related N- acetyltransferase. (170 aa)
Sros_9310KEGG: pca:Pcar_1903 aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (355 aa)
Sros_9311Aspartate kinase; KEGG: dat:HRM2_35870 LysC; Belongs to the aspartokinase family. (424 aa)
argG-2KEGG: lch:Lcho_0912 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (482 aa)
Sros_0061Homoserine O-acetyltransferase; KEGG: bra:BRADO5867 hypothetical protein; Belongs to the AB hydrolase superfamily. MetX family. (338 aa)
pheAKEGG: ade:Adeh_1779 prephenate dehydratase. (306 aa)
serSSerine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (420 aa)
Sros_0327Succinyl-diaminopimelate desuccinylase; KEGG: dde:Dde_1186 M20/M25/M40 family peptidase. (434 aa)
egtDConserved hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (326 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (279 aa)
Sros_0440Diaminopimelate decarboxylase-like protein; KEGG: bar:GBAA1438 diaminopimelate decarboxylase. (276 aa)
Sros_0500Phosphoserine phosphatase; KEGG: scl:sce0663 hypothetical protein. (407 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa)
Sros_0542Phosphoserine phosphatase-like protein; KEGG: afw:Anae109_1214 HAD family hydrolase. (289 aa)
Sros_0724KEGG: scl:sce1370 dihydrofolate reductase family protein. (197 aa)
Sros_0841KEGG: scl:sce6636 hypothetical protein. (189 aa)
serCPhosphoserine aminotransferase-like protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (369 aa)
Sros_1023Bifunctional deaminase-reductase-like protein; KEGG: mes:Meso_2196 bifunctional deaminase- reductase-like. (178 aa)
Sros_1141Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (371 aa)
folD-2Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
Sros_1268Aminoacylase; KEGG: bsu:BSU29290 hypothetical protein. (412 aa)
Sros_1518Peptidase M20; KEGG: ade:Adeh_0863 peptidase M20. (448 aa)
Sros_1634Hypothetical protein; KEGG: acp:A2cp1_2970 asparagine synthase. (552 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (460 aa)
Sros_1638KEGG: gme:Gmet_1629 homoserine dehydrogenase. (430 aa)
Sros_1649L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (336 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
Sros_1725Mov34/MPN/PAD-1; KEGG: nmu:Nmul_A0971 Mov34/MPN/PAD-1. (138 aa)
Sros_1727Molybdopterin synthase subunit MoaD; KEGG: scl:sce5755 hypothetical protein. (92 aa)
Sros_1728KEGG: eba:ebA896 cysteine synthase B. (315 aa)
Sros_1760Glutamate--ammonia ligase; KEGG: acr:Acry_2393 glutamine synthetase, catalytic region. (447 aa)
Sros_1779KEGG: bbr:BB2432 allantoate amidohydrolase. (387 aa)
Sros_2030Hypothetical protein; KEGG: vei:Veis_2871 aminoglycoside phosphotransferase. (285 aa)
Sros_2040Glutamate--ammonia ligase; KEGG: hypothetical protein; K01915 glutamine synthetase. (337 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (245 aa)
Sros_2136KEGG: pla:Plav_3174 GCN5-related N- acetyltransferase. (169 aa)
Sros_2137Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1245 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (268 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (569 aa)
Sros_2330KEGG: rle:RL4385 ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (403 aa)
Sros_2361KEGG: bja:bll4205 hypothetical protein; Belongs to the DapA family. (351 aa)
Sros_2367Dihydrodipicolinate synthase/N-acetylneuraminate lyase-like protein; KEGG: acp:A2cp1_4217 dihydrodipicolinate synthase. (333 aa)
Sros_2502KEGG: csa:Csal_0030 acetylornithine deacetylase. (418 aa)
Sros_2587Cystathionine gamma-synthase; KEGG: cko:CKO_04984 hypothetical protein. (390 aa)
Sros_2589KEGG: mlo:mlr3510 threonine dehydratase. (303 aa)
Sros_2611KEGG: sat:SYN_01628 glutamine synthetase. (453 aa)
Sros_2629KEGG: dal:Dalk_5100 glutamine synthetase, type I. (474 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa)
Sros_2740KEGG: bsu:BSU02410 homocysteine methyltransferase. (287 aa)
Sros_2788KEGG: afw:Anae109_2667 5,10- methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (310 aa)
Sros_2799Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa)
carACarbamoyl-phosphate synthase (glutamine- hydrolyzing); KEGG: hch:HCH_01227 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (400 aa)
carBKEGG: geo:Geob_3271 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1097 aa)
hisAPhosphoribosylanthranilate isomerase; KEGG: plu:plu0797 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4- carboxamide isomerase. (240 aa)
Sros_2916KEGG: glutamate-ammonia ligase; Belongs to the glutamine synthetase family. (469 aa)
trpCKEGG: afw:Anae109_0373 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (269 aa)
trpBTryptophan synthase; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (264 aa)
Sros_2949KEGG: afw:Anae109_0854 glutamate synthase (ferredoxin). (1501 aa)
Sros_2950KEGG: aba:Acid345_3679 glutamate synthase (NADH) small subunit. (492 aa)
Sros_2998Prephenate dehydrogenase-like protein; KEGG: bpt:Bpet1887 hypothetical protein. (357 aa)
Sros_3052KEGG: vei:Veis_4212 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (584 aa)
Sros_3160Peptidase M20; KEGG: dal:Dalk_4445 peptidase M20. (421 aa)
Sros_3264KEGG: dac:Daci_3022 deaminase-reductase domain- containing protein. (180 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (626 aa)
Sros_3531KEGG: mes:Meso_2469 asparagine synthase (glutamine- hydrolyzing). (596 aa)
Sros_3534KEGG: rlt:Rleg2_4009 D-isomer specific 2- hydroxyacid dehydrogenase NAD-binding. (333 aa)
trpFKEGG: sil:SPO0806 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (211 aa)
Sros_3604Peptidase M20; KEGG: dal:Dalk_4445 peptidase M20. (434 aa)
Sros_3644KEGG: mlo:mlr0926 hypothetical protein. (190 aa)
Sros_3665KEGG: bsu:BSU37740 hypothetical protein. (187 aa)
Sros_3696KEGG: afw:Anae109_3251 deaminase-reductase domain- containing protein. (181 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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