STRINGSTRING
Sros_6103 Sros_6103 Sros_5877 Sros_5877 Sros_5747 Sros_5747 Sros_5572 Sros_5572 Sros_5566 Sros_5566 Sros_5565 Sros_5565 Sros_5561 Sros_5561 Sros_5424 Sros_5424 Sros_5355 Sros_5355 Sros_5225 Sros_5225 Sros_5214 Sros_5214 Sros_5177 Sros_5177 Sros_4990 Sros_4990 Sros_4900 Sros_4900 Sros_4871 Sros_4871 Sros_4610 Sros_4610 Sros_4608 Sros_4608 Sros_4542 Sros_4542 Sros_4541 Sros_4541 Sros_4434 Sros_4434 Sros_4362 Sros_4362 Sros_4360 Sros_4360 Sros_4359 Sros_4359 Sros_4177 Sros_4177 Sros_4157 Sros_4157 Sros_3928 Sros_3928 Sros_3862 Sros_3862 Sros_3844 Sros_3844 Sros_3805 Sros_3805 Sros_3773 Sros_3773 dxs dxs Sros_3496 Sros_3496 Sros_3405 Sros_3405 Sros_3262 Sros_3262 Sros_3085 Sros_3085 Sros_3076 Sros_3076 Sros_3048 Sros_3048 Sros_3047 Sros_3047 Sros_3046 Sros_3046 Sros_3006 Sros_3006 Sros_2977 Sros_2977 thiE thiE Sros_2782 Sros_2782 thiG thiG thiI thiI Sros_2643 Sros_2643 Sros_2521 Sros_2521 Sros_2503 Sros_2503 Sros_2469 Sros_2469 glpK glpK Sros_2373 Sros_2373 Sros_2336 Sros_2336 Sros_2322 Sros_2322 Sros_2272 Sros_2272 Sros_2260 Sros_2260 Sros_2259 Sros_2259 Sros_2251 Sros_2251 Sros_2138 Sros_2138 Sros_2094 Sros_2094 Sros_2064 Sros_2064 Sros_2063 Sros_2063 Sros_2062 Sros_2062 Sros_1994 Sros_1994 Sros_1901 Sros_1901 Sros_1620 Sros_1620 Sros_1593 Sros_1593 Sros_1577 Sros_1577 Sros_1496 Sros_1496 Sros_1482 Sros_1482 Sros_1330 Sros_1330 Sros_1254 Sros_1254 Sros_9074 Sros_9074 Sros_8927 Sros_8927 Sros_8847 Sros_8847 Sros_8843 Sros_8843 Sros_8602 Sros_8602 Sros_8524 Sros_8524 Sros_8496 Sros_8496 Sros_8492 Sros_8492 Sros_8487 Sros_8487 Sros_8397 Sros_8397 Sros_8330 Sros_8330 Sros_8256 Sros_8256 Sros_8216 Sros_8216 Sros_8196 Sros_8196 Sros_8195 Sros_8195 Sros_8026 Sros_8026 thiL thiL Sros_9365 Sros_9365 Sros_9123 Sros_9123 Sros_8003 Sros_8003 Sros_8001 Sros_8001 Sros_7931 Sros_7931 Sros_7928 Sros_7928 Sros_1176 Sros_1176 pdxH pdxH serC serC Sros_0947 Sros_0947 Sros_0868 Sros_0868 Sros_0833 Sros_0833 Sros_0560 Sros_0560 Sros_0467 Sros_0467 Sros_0466 Sros_0466 Sros_0408 Sros_0408 Sros_0124 Sros_0124 Sros_0123 Sros_0123 Sros_0094 Sros_0094 Sros_7866 Sros_7866 Sros_7854 Sros_7854 Sros_7846 Sros_7846 Sros_7718 Sros_7718 Sros_7703 Sros_7703 Sros_7609 Sros_7609 Sros_7585 Sros_7585 Sros_7504 Sros_7504 glpK-3 glpK-3 glpK-2 glpK-2 Sros_7455 Sros_7455 Sros_7369 Sros_7369 Sros_7368 Sros_7368 Sros_7340 Sros_7340 Sros_7122 Sros_7122 Sros_6869 Sros_6869 Sros_6775 Sros_6775 dxs-2 dxs-2 Sros_6724 Sros_6724 Sros_6684 Sros_6684 Sros_6682 Sros_6682 Sros_6630 Sros_6630 Sros_6610 Sros_6610 Sros_6354 Sros_6354 Sros_6338 Sros_6338 Sros_6308 Sros_6308 Sros_6284 Sros_6284 pdxS pdxS pdxT pdxT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_6103KEGG: aba:Acid345_1901 beta-lactamase-like. (231 aa)
Sros_5877Dehydrogenase-like protein; KEGG: mlo:mlr2436 NADH-dependent dyhydrogenase. (355 aa)
Sros_5747KEGG: gsu:GSU2762 glycerol kinase; Belongs to the FGGY kinase family. (488 aa)
Sros_5572KEGG: smd:Smed_3959 inositol-phosphate phosphatase. (267 aa)
Sros_5566KEGG: sus:Acid_1483 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family. (612 aa)
Sros_5565KEGG: sus:Acid_1480 myo-inositol catabolism IolB domain-containing protein. (282 aa)
Sros_5561KEGG: sus:Acid_1485 inositol 2-dehydrogenase. (323 aa)
Sros_5424KEGG: hypothetical protein. (311 aa)
Sros_5355KEGG: afw:Anae109_1686 hypothetical protein. (145 aa)
Sros_5225Hypothetical protein. (154 aa)
Sros_5214KEGG: afw:Anae109_2478 inositol monophosphatase. (267 aa)
Sros_5177KEGG: bja:blr3078 hypothetical protein. (266 aa)
Sros_4990KEGG: spe:Spro_2575 oxidoreductase domain- containing protein. (414 aa)
Sros_4900KEGG: afw:Anae109_1654 glyoxalase/bleomycin resistance protein/dioxygenase. (156 aa)
Sros_4871KEGG: hypothetical protein. (209 aa)
Sros_4610D-lactate dehydrogenase (cytochrome); KEGG: aba:Acid345_2723 FAD linked oxidase-like. (928 aa)
Sros_4608KEGG: mno:Mnod_6025 fumarylacetoacetate (FAA) hydrolase. (222 aa)
Sros_4542KEGG: sil:SPO3081 glyoxalase family protein. (145 aa)
Sros_4541Hypothetical protein. (177 aa)
Sros_4434KEGG: cak:Caul_2304 fatty acid hydroxylase. (303 aa)
Sros_4362KEGG: oan:Oant_2460 carbohydrate kinase FGGY. (526 aa)
Sros_4360KEGG: dac:Daci_1119 FAD linked oxidase domain- containing protein. (520 aa)
Sros_4359KEGG: bmj:BMULJ_03935 glycerol uptake operon antiterminator. (203 aa)
Sros_4177Putative transcriptional activator, TenA family; KEGG: ret:RHE_CH00249 TenA family transcription regulator. (222 aa)
Sros_4157KEGG: mno:Mnod_7784 transcriptional activator, TenA family. (222 aa)
Sros_3928Acyltransferase; KEGG: abo:ABO_2742 acyltransferase; Belongs to the long-chain O-acyltransferase family. (478 aa)
Sros_3862KEGG: hypothetical protein. (390 aa)
Sros_3844Putative transcriptional activator, TenA family; KEGG: mms:mma_0874 TenA family transcription regulator. (228 aa)
Sros_3805KEGG: bbt:BBta_3710 putative phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (213 aa)
Sros_3773Pyridoxal 5'-phosphate synthase; KEGG: rso:RSc0767 pyridoxamine 5'-phosphate oxidase. (216 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (647 aa)
Sros_3496KEGG: csa:Csal_0643 mannitol dehydrogenase-like protein. (497 aa)
Sros_3405Hypothetical protein. (164 aa)
Sros_3262Hypothetical protein; KEGG: bph:Bphy_6190 hemerythrin HHE cation binding domain-containing protein. (155 aa)
Sros_30855-carboxymethyl-2-hydroxymuconateDelta- isomerase; KEGG: sus:Acid_4970 5-oxopent-3-ene-1,2,5- tricarboxylate decarboxylase. (249 aa)
Sros_3076Dehydrogenase-like protein; KEGG: vei:Veis_1396 oxidoreductase domain- containing protein. (342 aa)
Sros_3048Glycerone kinase; KEGG: acr:Acry_2616 dihydroxyacetone kinase, DhaK subunit. (330 aa)
Sros_3047KEGG: gdj:Gdia_2329 dihydroxyacetone kinase, L subunit. (213 aa)
Sros_3046KEGG: dde:Dde_1180 phosphoenolpyruvate--protein phosphotransferase. (123 aa)
Sros_3006KEGG: gbe:GbCGDNIH1_1166 metal-dependent hydrolase. (312 aa)
Sros_2977KEGG: eca:ECA3240 inositol monophosphatase. (270 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (213 aa)
Sros_2782KEGG: har:HEAR0262 putative thiamine biosynthesis protein ThiS. (66 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (252 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (400 aa)
Sros_2643KEGG: aba:Acid345_0055 hypothetical protein. (301 aa)
Sros_2521KEGG: rec:RHECIAT_PC0000780 putative oxidoreductase protein. (284 aa)
Sros_2503KEGG: pca:Pcar_2523 rhodanese-related sulfurtransferase. (112 aa)
Sros_2469Amidohydrolase 2; KEGG: mes:Meso_1610 amidohydrolase 2. (277 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (505 aa)
Sros_2373Hypothetical protein; KEGG: sal:Sala_0307 amidohydrolase 2. (239 aa)
Sros_2336Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa)
Sros_2322KEGG: cak:Caul_2877 oxidoreductase domain- containing protein. (309 aa)
Sros_2272KEGG: bha:BH3627 hypothetical protein. (282 aa)
Sros_2260KEGG: afw:Anae109_2921 D-lactate dehydrogenase (cytochrome). (485 aa)
Sros_2259KEGG: ade:Adeh_2866 FAD linked oxidase-like. (437 aa)
Sros_2251KEGG: bcs:BCAN_B0406 4,5,-dihydroxyphthalate dehydrogenase. (332 aa)
Sros_2138Putative transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (221 aa)
Sros_2094KEGG: swi:Swit_3652 hypothetical protein. (128 aa)
Sros_2064KEGG: nar:Saro_3751 coenzyme A transferase. (286 aa)
Sros_2063KEGG: nar:Saro_3752 acyl CoA:acetate/3-ketoacid CoA transferase beta subunit-like protein. (286 aa)
Sros_2062KEGG: nar:Saro_3754 2-nitropropane dioxygenase, NPD. (369 aa)
Sros_1994KEGG: swi:Swit_2101 hypothetical protein. (120 aa)
Sros_1901Rhodanese-related sulfurtransferase-like protein; KEGG: aba:Acid345_3083 rhodanese/sulfurtransferase- like protein. (201 aa)
Sros_1620KEGG: psa:PST_2854 glyoxalase family protein. (133 aa)
Sros_1593KEGG: mmw:Mmwyl1_3508 oxidoreductase domain- containing protein. (332 aa)
Sros_1577KEGG: mno:Mnod_1197 beta-lactamase domain protein. (272 aa)
Sros_1496Dehydrogenase-like protein; KEGG: bja:blr3664 putative oxidoreductase. (681 aa)
Sros_1482Nucleic-acid-binding protein containing a Zn- ribbon-like protein; KEGG: reh:H16_A0870 hypothetical protein. (295 aa)
Sros_1330KEGG: gur:Gura_2928 beta-lactamase domain- containing protein. (205 aa)
Sros_1254KEGG: oca:OCAR_5440 isocitrate dehydrogenase, NADP- dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
Sros_9074KEGG: hne:HNE_3461 metallo-beta-lactamase family protein. (637 aa)
Sros_8927KEGG: swi:Swit_3624 hypothetical protein. (134 aa)
Sros_8847KEGG: rso:RS01759 fumarylacetoacetase. (378 aa)
Sros_8843Hypothetical protein; KEGG: geo:Geob_0328 glyoxalase/bleomycin resistance protein/dioxygenase. (215 aa)
Sros_8602KEGG: cvi:CV_1577 inositol monophosphatase family protein. (255 aa)
Sros_8524Z-farnesyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (255 aa)
Sros_8496KEGG: bme:BMEII0574 myo-inositol 2-dehydrogenase. (325 aa)
Sros_8492KEGG: sus:Acid_1480 myo-inositol catabolism IolB domain-containing protein. (273 aa)
Sros_8487Fructose-bisphosphatase; KEGG: dat:HRM2_21890 GlpX. (344 aa)
Sros_8397Zn-dependent hydrolase including glyoxylase- like protein; KEGG: glo:Glov_3342 beta-lactamase domain protein. (238 aa)
Sros_8330KEGG: ade:Adeh_1287 histidinol-phosphate phosphatase. (267 aa)
Sros_8256KEGG: bha:BH0710 hypothetical protein. (409 aa)
Sros_8216KEGG: spe:Spro_0639 5-carboxymethyl-2- hydroxymuconate delta-isomerase. (281 aa)
Sros_8196KEGG: swi:Swit_3318 hypothetical protein. (319 aa)
Sros_8195Dehydratase; KEGG: swi:Swit_3320 dehydratase. (136 aa)
Sros_8026KEGG: dvl:Dvul_2107 5-carboxymethyl-2- hydroxymuconate delta-isomerase. (258 aa)
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (318 aa)
Sros_9365KEGG: sme:SM_b20249 putative myo-inositol-1- phosphate synthase. (359 aa)
Sros_9123KEGG: scl:sce1698 putative pterin-4-alpha- carbinolamine dehydratase. (112 aa)
Sros_8003KEGG: sfu:Sfum_1692 phosphomethylpyrimidine kinase. (272 aa)
Sros_8001KEGG: bha:BH2498 hypothetical protein. (521 aa)
Sros_7931KEGG: reh:H16_B2289 3-carboxy-cis,cis-muconate cyclo-isomerase. (452 aa)
Sros_7928KEGG: pfl:PFL_1317 3-oxoadipate:succinyl-CoA transferase, A subunit. (273 aa)
Sros_1176KEGG: scl:sce0787 hypothetical protein. (563 aa)
pdxHPyridoxal 5'-phosphate synthase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (217 aa)
serCPhosphoserine aminotransferase-like protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (369 aa)
Sros_0947KEGG: rlt:Rleg2_1526 hypothetical protein. (236 aa)
Sros_0868KEGG: afw:Anae109_3449 inositol-phosphate phosphatase. (267 aa)
Sros_0833Hypothetical protein. (143 aa)
Sros_05605-carboxymethyl-2-hydroxymuconateDelta- isomerase; KEGG: bxe:Bxe_C0991 putative fumarylacetoacetate (FAA) hydrolase. (281 aa)
Sros_0467KEGG: pzu:PHZ_c2735 metallo-beta-lactamase family protein. (262 aa)
Sros_0466KEGG: rpa:RPA3189 NUDIX hydrolase. (275 aa)
Sros_0408Zn-dependent hydrolase including glyoxylase- like protein; KEGG: sus:Acid_1471 beta-lactamase domain- containing protein. (263 aa)
Sros_0124Rhodanese-related sulfurtransferase-like protein; KEGG: tbd:Tbd_2399 rhodanese-like protein. (110 aa)
Sros_0123Putative transcriptional activator, TenA family; KEGG: bha:BH2679 transcriptional regulator of extracellular enzyme genes. (201 aa)
Sros_0094KEGG: ara:Arad_3055 lactoylglutathione lyase protein. (115 aa)
Sros_7866Hypothetical protein. (145 aa)
Sros_7854Protocatechuate 3 4-dioxygenase beta subunit- like protein; KEGG: smd:Smed_4070 intradiol ring-cleavage dioxygenase. (277 aa)
Sros_7846KEGG: gsu:GSU2762 glycerol kinase; Belongs to the FGGY kinase family. (477 aa)
Sros_7718Putative lyase; KEGG: cti:RALTA_B0885 putative lyase. (136 aa)
Sros_7703KEGG: aca:ACP_1052 putative pterin-4-alpha- carbinolamine dehydratase. (96 aa)
Sros_7609KEGG: pol:Bpro_0627 protocatechuate 3,4- dioxygenase, beta subunit. (225 aa)
Sros_7585KEGG: bam:Bamb_5828 beta-lactamase domain- containing protein. (266 aa)
Sros_7504KEGG: nar:Saro_2598 5-carboxymethyl-2- hydroxymuconate delta-isomerase. (281 aa)
glpK-3Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (505 aa)
glpK-2Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (505 aa)
Sros_7455KEGG: avi:Avi_5579 hypothetical protein. (227 aa)
Sros_7369KEGG: aca:ACP_0002 iron-sulfur cluster binding protein. (470 aa)
Sros_7368Conserved hypothetical protein; KEGG: aca:ACP_0001 YkgG family protein. (316 aa)
Sros_7340KEGG: mlo:mlr1197 hypothetical protein. (115 aa)
Sros_7122KEGG: bpd:BURPS668_A0963 rhodanese domain- containing protein. (159 aa)
Sros_6869KEGG: bpd:BURPS668_3923 oxidoreductase YdgJ. (345 aa)
Sros_6775KEGG: csa:Csal_1824 inositol-1(or 4)- monophosphatase. (264 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa)
Sros_6724KEGG: ara:Arad_4620 oxidoreductase protein. (380 aa)
Sros_6684KEGG: vei:Veis_2018 FAD dependent oxidoreductase. (516 aa)
Sros_6682KEGG: pla:Plav_1669 alkylglycerone-phosphate synthase. (521 aa)
Sros_6630KEGG: bra:BRADO2585 hypothetical protein. (120 aa)
Sros_6610KEGG: gbe:GbCGDNIH1_0668 vanillate demethylase oxygenase subunit. (380 aa)
Sros_6354KEGG: scl:sce0752 putative glycolate oxidase. (453 aa)
Sros_6338Putative transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. (231 aa)
Sros_6308KEGG: maq:Maqu_3067 hypothetical protein; Belongs to the long-chain O-acyltransferase family. (490 aa)
Sros_6284KEGG: pla:Plav_1652 beta-lactamase domain- containing protein. (312 aa)
pdxSSnz1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (304 aa)
pdxTSNO glutamine amidotransferase family; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (196 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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