STRINGSTRING
Sros_3526 Sros_3526 argG-2 argG-2 tilS tilS panC panC Sros_9016 Sros_9016 argS argS Sros_8684 Sros_8684 Sros_8682 Sros_8682 metG metG Sros_8601 Sros_8601 cysS-2 cysS-2 Sros_8114 Sros_8114 Sros_8113 Sros_8113 mnmA mnmA gltX gltX coaD coaD valS-2 valS-2 nadD nadD Sros_7214 Sros_7214 leuS leuS valS valS cysH cysH Sros_6500 Sros_6500 argG argG tyrS tyrS mshC mshC Sros_5918 Sros_5918 Sros_5898 Sros_5898 Sros_5439 Sros_5439 Sros_5254 Sros_5254 Sros_4842 Sros_4842 Sros_4841 Sros_4841 Sros_4831 Sros_4831 Sros_4830 Sros_4830 Sros_4829 Sros_4829 Sros_4828 Sros_4828 Sros_4822 Sros_4822 Sros_4809 Sros_4809 Sros_4807 Sros_4807 Sros_4805 Sros_4805 Sros_4804 Sros_4804 Sros_4681 Sros_4681 Sros_4169 Sros_4169 Sros_3803 Sros_3803 nadE-2 nadE-2 Sros_3531 Sros_3531 ileS ileS thiI thiI nadE nadE Sros_2556 Sros_2556 Sros_2129 Sros_2129 Sros_1634 Sros_1634 Sros_1613 Sros_1613 trpS trpS guaA guaA cysS cysS Sros_0436 Sros_0436
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_3526Hypothetical protein; KEGG: hha:Hhal_2190 UspA domain-containing protein. (288 aa)
argG-2KEGG: lch:Lcho_0912 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (482 aa)
tilStRNA(Ile)-lysidine synthetase-like protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (337 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa)
Sros_9016Hypothetical protein; KEGG: hha:Hhal_2190 UspA domain-containing protein. (315 aa)
argSArginine--tRNA ligase; KEGG: scl:sce7660 hypothetical protein. (584 aa)
Sros_8684KEGG: swi:Swit_5329 phosphoadenosine phosphosulfate reductase. (278 aa)
Sros_8682KEGG: avi:Avi_9567 hypothetical protein. (288 aa)
metGtRNA synthetase class I (I, L, M and V); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (593 aa)
Sros_8601KEGG: noc:Noc_2289 sulfate adenylyltransferase subunit 2. (304 aa)
cysS-2Cysteine--tRNA ligase; KEGG: bur:Bcep18194_B0590 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (459 aa)
Sros_8114KEGG: sat:SYN_02636 electron transfer flavoprotein beta-subunit. (259 aa)
Sros_8113KEGG: met:M446_2006 electron transfer flavoprotein alpha subunit. (317 aa)
mnmAtRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (356 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (455 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa)
valS-2valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (861 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (206 aa)
Sros_7214KEGG: swi:Swit_3995 hypothetical protein. (589 aa)
leuSKEGG: glo:Glov_2116 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (828 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (845 aa)
cysHPhosphoadenosine phosphosulfate; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (242 aa)
Sros_6500KEGG: gbm:Gbem_1778 asparagine synthase (glutamine- hydrolyzing). (638 aa)
argGKEGG: bha:BH3187 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (422 aa)
mshCCysteine--tRNA ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (407 aa)
Sros_5918KEGG: sme:SMa1100 hypothetical protein. (152 aa)
Sros_5898Kef-type K+ transport systems membrane components-like protein; KEGG: scl:sce2508 putative cation/hydrogen exchanger. (683 aa)
Sros_5439Universal stress protein UspA and related nucleotide-binding protein-like protein; KEGG: hha:Hhal_2190 UspA domain-containing protein. (284 aa)
Sros_5254Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (597 aa)
Sros_4842Hypothetical protein; KEGG: hha:Hhal_2190 UspA domain-containing protein. (229 aa)
Sros_4841Hypothetical protein; KEGG: aeh:Mlg_0315 UspA domain-containing protein. (302 aa)
Sros_4831KEGG: scl:sce0123 hypothetical protein. (292 aa)
Sros_4830KEGG: rfr:Rfer_2148 hypothetical protein. (283 aa)
Sros_4829KEGG: tbd:Tbd_2614 universal stress protein. (285 aa)
Sros_4828Hypothetical protein; KEGG: aeh:Mlg_0315 UspA domain-containing protein. (292 aa)
Sros_4822KEGG: hha:Hhal_1862 UspA domain-containing protein. (289 aa)
Sros_4809Hypothetical protein; KEGG: hha:Hhal_2190 UspA domain-containing protein. (282 aa)
Sros_4807Universal stress protein UspA and related nucleotide-binding protein-like protein; KEGG: hha:Hhal_1862 UspA domain-containing protein. (288 aa)
Sros_4805Hypothetical protein; KEGG: mca:MCA1759 universal stress protein. (273 aa)
Sros_4804Universal stress protein UspA and related nucleotide-binding protein-like protein; KEGG: hha:Hhal_2190 UspA domain-containing protein. (299 aa)
Sros_4681Universal stress protein UspA and related nucleotide-binding protein-like protein; KEGG: hha:Hhal_2190 UspA domain-containing protein. (288 aa)
Sros_4169Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (619 aa)
Sros_3803KEGG: mrd:Mrad2831_0205 osmosensitive K+ channel signal transduction histidine kinase. (846 aa)
nadE-2NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (276 aa)
Sros_3531KEGG: mes:Meso_2469 asparagine synthase (glutamine- hydrolyzing). (596 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1054 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (400 aa)
nadENAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (597 aa)
Sros_2556Tryptophan--tRNA ligase; KEGG: aha:AHA_3183 tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (321 aa)
Sros_2129KEGG: xac:XAC1253 bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (317 aa)
Sros_1634Hypothetical protein; KEGG: acp:A2cp1_2970 asparagine synthase. (552 aa)
Sros_1613KEGG: rce:RC1_2026 deoxyribodipyrimidine photolyase family protein; Belongs to the DNA photolyase family. (425 aa)
trpSTryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa)
guaAGMP synthase C terminal domain protein; Catalyzes the synthesis of GMP from XMP. (523 aa)
cysSCysteine--tRNA ligase; KEGG: gsu:GSU3365 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa)
Sros_0436KEGG: mrd:Mrad2831_0205 osmosensitive K+ channel signal transduction histidine kinase. (851 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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