STRINGSTRING
Sros_8308 Sros_8308 hemL hemL Sros_0417 Sros_0417 pat pat egtE egtE serC serC Sros_9381 Sros_9381 Sros_9379 Sros_9379 Sros_9368 Sros_9368 Sros_9291 Sros_9291 Sros_9236 Sros_9236 Sros_9167 Sros_9167 kynU kynU kbl kbl Sros_8727 Sros_8727 Sros_8687 Sros_8687 Sros_8563 Sros_8563 Sros_8497 Sros_8497 Sros_8434 Sros_8434 Sros_1066 Sros_1066 Sros_1177 Sros_1177 Sros_1200 Sros_1200 Sros_1440 Sros_1440 Sros_1519 Sros_1519 glyA glyA Sros_1947 Sros_1947 Sros_1956 Sros_1956 Sros_2147 Sros_2147 Sros_2228 Sros_2228 Sros_2330 Sros_2330 Sros_2363 Sros_2363 Sros_2375 Sros_2375 Sros_2555 Sros_2555 Sros_2586 Sros_2586 Sros_2587 Sros_2587 Sros_2669 Sros_2669 hisC hisC Sros_3086 Sros_3086 Sros_3143 Sros_3143 Sros_3418 Sros_3418 Sros_3487 Sros_3487 selA selA Sros_3925 Sros_3925 gcvP gcvP Sros_4267 Sros_4267 Sros_4268 Sros_4268 Sros_4459 Sros_4459 Sros_4546 Sros_4546 Sros_4973 Sros_4973 Sros_5114 Sros_5114 Sros_5187 Sros_5187 Sros_5205 Sros_5205 Sros_5231 Sros_5231 Sros_5610 Sros_5610 Sros_5894 Sros_5894 Sros_5956 Sros_5956 Sros_5983 Sros_5983 argD argD Sros_6495 Sros_6495 Sros_6569 Sros_6569 Sros_6583 Sros_6583 glyA-2 glyA-2 Sros_6950 Sros_6950 Sros_7120 Sros_7120 Sros_7662 Sros_7662 Sros_7670 Sros_7670 Sros_7678 Sros_7678 Sros_7698 Sros_7698 Sros_7699 Sros_7699 Sros_8009 Sros_8009 Sros_8110 Sros_8110
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_8308KEGG: mxa:MXAN_1258 8-amino-7-oxononanoate synthase. (389 aa)
hemLKEGG: aeh:Mlg_0806 glutamate-1-semialdehyde 2,1- aminomutase. (437 aa)
Sros_0417KEGG: mpo:Mpop_0649 putative transcriptional regulator, GntR family. (425 aa)
patHistidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (353 aa)
egtEclass-V aminotransferase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. (409 aa)
serCPhosphoserine aminotransferase-like protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (369 aa)
Sros_9381KEGG: dvm:DvMF_0572 threonine aldolase. (352 aa)
Sros_9379Putative transcriptional regulator, GntR family; KEGG: mxa:MXAN_0212 aminotransferase, class I and II family protein. (441 aa)
Sros_9368KEGG: abo:ABO_0256 7,8-diaminononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (406 aa)
Sros_9291Aminotransferase; KEGG: csa:Csal_1034 aminotransferase. (426 aa)
Sros_9236KEGG: cvi:CV_0803 5-aminolevulinate synthase. (400 aa)
Sros_9167Cysteine desulfurase; KEGG: scl:sce1210 hypothetical protein. (433 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (407 aa)
kblGlycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (390 aa)
Sros_8727KEGG: dvl:Dvul_1143 GntR family transcriptional regulator. (473 aa)
Sros_8687Cysteine desulfurase; KEGG: afw:Anae109_1098 aminotransferase class V. (399 aa)
Sros_8563KEGG: afw:Anae109_3845 cystathionine gamma-lyase. (379 aa)
Sros_8497KEGG: ade:Adeh_2233 GntR family transcriptional regulator. (481 aa)
Sros_8434KEGG: ank:AnaeK_3893 aminotransferase class I and II. (359 aa)
Sros_1066KEGG: ppd:Ppro_2189 aminotransferase, class I and II. (401 aa)
Sros_1177KEGG: scl:sce6892 hypothetical protein. (474 aa)
Sros_1200KEGG: pca:Pcar_1141 pyridoxal-phosphate-dependent aminotransferase enzyme; Belongs to the DegT/DnrJ/EryC1 family. (374 aa)
Sros_1440KEGG: bph:Bphy_5923 pyridoxal-dependent decarboxylase. (474 aa)
Sros_1519KEGG: bcj:BCAS0137 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
Sros_1947Aminotransferase; KEGG: sus:Acid_7662 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
Sros_1956KEGG: aba:Acid345_1534 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
Sros_2147KEGG: dde:Dde_0621 GntR family transcriptional regulator. (453 aa)
Sros_2228KEGG: sme:SMc04326 putative aminotransferase protein. (379 aa)
Sros_2330KEGG: rle:RL4385 ornithine--oxo-acid transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (403 aa)
Sros_2363Glutamine--scyllo-inositol transaminase; KEGG: mes:Meso_3973 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (379 aa)
Sros_2375KEGG: pen:PSEEN2473 PLP-dependent transaminase; Belongs to the DegT/DnrJ/EryC1 family. (415 aa)
Sros_2555KEGG: dvm:DvMF_0572 threonine aldolase. (352 aa)
Sros_2586KEGG: kpn:KPN_00421 GntR family transcriptional regulator. (478 aa)
Sros_2587Cystathionine gamma-synthase; KEGG: cko:CKO_04984 hypothetical protein. (390 aa)
Sros_2669KEGG: gur:Gura_1493 aminotransferase, class V. (378 aa)
hisCKEGG: bur:Bcep18194_C7445 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa)
Sros_3086Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pca:Pcar_0266 glutamate-1-semialdehyde-2,1- aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)
Sros_3143Aminotransferase; KEGG: bsu:BSU31440 aminotransferase. (381 aa)
Sros_3418KEGG: dal:Dalk_0154 pyridoxal-dependent decarboxylase. (472 aa)
Sros_3487KEGG: scl:sce8130 selenocysteine lyase / isopenicillin N epimerase. (426 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (429 aa)
Sros_3925KEGG: sil:SPO3529 serine hydroxymethyltransferase. (417 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (951 aa)
Sros_4267KEGG: ank:AnaeK_0047 transcriptional regulator, GntR family with aminotransferase domain. (454 aa)
Sros_4268KEGG: scl:sce8911 class-V aminotransferase. (430 aa)
Sros_4459KEGG: ank:AnaeK_4479 aminotransferase class V. (341 aa)
Sros_4546KEGG: aca:ACP_2295 pyridoxal-dependent decarboxylase conserved domain protein. (472 aa)
Sros_4973KEGG: bbt:BBta_3802 putative aminotransferase. (437 aa)
Sros_5114KEGG: mrd:Mrad2831_2878 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (436 aa)
Sros_5187KEGG: scl:sce8911 class-V aminotransferase. (395 aa)
Sros_52058-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase; KEGG: dsh:Dshi_2228 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (517 aa)
Sros_5231KEGG: rpi:Rpic_3403 transcriptional regulator, GntR family with aminotransferase domain. (466 aa)
Sros_5610Putative transcriptional regulator, GntR family; KEGG: esa:ESA_02823 hypothetical protein. (468 aa)
Sros_5894Aminotransferase; KEGG: nar:Saro_0248 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (407 aa)
Sros_5956KEGG: pzu:PHZ_c3113 transcriptional regulator, GntR family. (486 aa)
Sros_5983SufS subfamily cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (419 aa)
argDKEGG: afw:Anae109_2686 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa)
Sros_6495KEGG: pen:PSEEN0254 TDP-4-oxo-6-deoxy-D-glucose transaminase; Belongs to the DegT/DnrJ/EryC1 family. (409 aa)
Sros_6569KEGG: mxa:MXAN_3751 aminotransferase, classes I and II. (394 aa)
Sros_6583KEGG: mxa:MXAN_1570 aminotransferase, class V. (425 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
Sros_6950Kynureninase; KEGG: ade:Adeh_3164 kynureninase. (403 aa)
Sros_7120KEGG: spe:Spro_3049 pyridoxal-dependent decarboxylase. (466 aa)
Sros_7662KEGG: hha:Hhal_1567 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (386 aa)
Sros_7670KEGG: bpe:BP2599 GntR family transcriptional regulator. (496 aa)
Sros_7678KEGG: pca:Pcar_2442 L-lysine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (433 aa)
Sros_7698KEGG: vei:Veis_2458 glycine dehydrogenase subunit 2. (519 aa)
Sros_7699Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (443 aa)
Sros_8009KEGG: sfu:Sfum_2670 cystathionine gamma-synthase. (406 aa)
Sros_8110Cysteine desulfurase; KEGG: rru:Rru_A1068 aminotransferase, class V. (387 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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