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hisH hisH Sros_2617 Sros_2617 Sros_5138 Sros_5138 Sros_4529 Sros_4529 Sros_3982 Sros_3982 guaA guaA Sros_0110 Sros_0110 Sros_3761 Sros_3761 pyrG pyrG carA carA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (209 aa)
Sros_2617KEGG: gbm:Gbem_1504 glutamine amidotransferase class-I. (233 aa)
Sros_5138GMP synthase - Glutamine amidotransferase domain- like protein; KEGG: gbm:Gbem_1504 glutamine amidotransferase class-I. (238 aa)
Sros_4529CTP synthase; KEGG: ent:Ent638_1664 hypothetical protein. (251 aa)
Sros_3982KEGG: scl:sce5044 anthranilate synthase. (715 aa)
guaAGMP synthase C terminal domain protein; Catalyzes the synthesis of GMP from XMP. (523 aa)
Sros_0110KEGG: gbe:GbCGDNIH1_0821 anthranilate synthase component II. (190 aa)
Sros_3761KEGG: oca:OCAR_5217 para-aminobenzoate synthase. (703 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (563 aa)
carACarbamoyl-phosphate synthase (glutamine- hydrolyzing); KEGG: hch:HCH_01227 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (400 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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