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| | serS | Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (420 aa) |
| | egtA | Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (408 aa) |
| | purD | KEGG: gbe:GbCGDNIH1_2297 phosphoribosylamine-- glycine ligase; Belongs to the GARS family. (410 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa) |
| | cysS | Cysteine--tRNA ligase; KEGG: gsu:GSU3365 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa) |
| | guaA | GMP synthase C terminal domain protein; Catalyzes the synthesis of GMP from XMP. (523 aa) |
| | Sros_1230 | KEGG: hha:Hhal_1017 glutamate--cysteine ligase, GCS2. (489 aa) |
| | sucC | Succinate--CoA ligase (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa) |
| | sucD | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa) |
| | trpS | Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa) |
| | Sros_1326 | KEGG: afw:Anae109_1479 biotin--acetyl-CoA- carboxylase ligase. (274 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa) |
| | Sros_1379 | Coenzyme F420-0 gamma-glutamyl ligase; KEGG: bpy:Bphyt_4255 F420-dependent oxidoreductase. (439 aa) |
| | Sros_1481 | KEGG: pla:Plav_0848 AMP-dependent synthetase and ligase. (525 aa) |
| | Sros_1485 | KEGG: pzu:PHZ_c2065 CoA synthetase, long-chain fatty acid:CoA ligase. (528 aa) |
| | Sros_1545 | KEGG: pla:Plav_3090 AMP-dependent synthetase and ligase. (549 aa) |
| | purC | KEGG: psa:PST_2788 phosphoribosylaminoimidazole- succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (276 aa) |
| | Sros_1722 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (428 aa) |
| | Sros_1760 | Glutamate--ammonia ligase; KEGG: acr:Acry_2393 glutamine synthetase, catalytic region. (447 aa) |
| | aspS | Aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. (428 aa) |
| | Sros_1890 | KEGG: rce:RC1_1843 propionate--CoA ligase. (695 aa) |
| | Sros_1992 | KEGG: swi:Swit_2100 AMP-dependent synthetase and ligase. (524 aa) |
| | Sros_2016 | KEGG: swi:Swit_3770 AMP-dependent synthetase and ligase. (534 aa) |
| | Sros_2040 | Glutamate--ammonia ligase; KEGG: hypothetical protein; K01915 glutamine synthetase. (337 aa) |
| | Sros_2101 | KEGG: swi:Swit_2105 AMP-dependent synthetase and ligase. (543 aa) |
| | proS | Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (580 aa) |
| | Sros_2202 | KEGG: bra:BRADO3743 putative O-succinylbenzoate-- CoA ligase. (483 aa) |
| | glyQS | Anticodon binding domain protein; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (461 aa) |
| | Sros_2556 | Tryptophan--tRNA ligase; KEGG: aha:AHA_3183 tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (321 aa) |
| | nadE | NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (597 aa) |
| | glnE | (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] (995 aa) |
| | Sros_2629 | KEGG: dal:Dalk_5100 glutamine synthetase, type I. (474 aa) |
| | lysS | Lysyl-tRNA synthetase (class II)-like protein; KEGG: lysine--tRNA ligase class II, chloroplast or mitochondrial; K04567 lysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family. (1098 aa) |
| | Sros_2696 | KEGG: mxa:MXAN_2959 putative long-chain-fatty-acid-- CoA ligase. (597 aa) |
| | Sros_2791 | KEGG: bph:Bphy_0164 YbaK/prolyl-tRNA synthetase associated region. (159 aa) |
| | carA | Carbamoyl-phosphate synthase (glutamine- hydrolyzing); KEGG: hch:HCH_01227 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (400 aa) |
| | carB | KEGG: geo:Geob_3271 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1097 aa) |
| | Sros_2815 | Phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (413 aa) |
| | murE | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (514 aa) |
| | murF | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (465 aa) |
| | murD | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (465 aa) |
| | murC | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (468 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1054 aa) |
| | Sros_2916 | KEGG: glutamate-ammonia ligase; Belongs to the glutamine synthetase family. (469 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (563 aa) |
| | Sros_3266 | KEGG: pla:Plav_0848 AMP-dependent synthetase and ligase. (511 aa) |
| | Sros_3344 | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; KEGG: bbt:BBta_3772 putative O-succinylbenzoate-- CoA ligase. (925 aa) |
| | Sros_3529 | Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (370 aa) |
| | Sros_3532 | Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (837 aa) |
| | ligA | DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (696 aa) |
| | Sros_3598 | Cysteinyl-tRNA synthetase-like protein; KEGG: spl:Spea_2684 cysteinyl-tRNA synthetase. (398 aa) |
| | nadE-2 | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (276 aa) |
| | Sros_3763 | KEGG: bxe:Bxe_A1419 benzoate-coenzyme A ligase. (522 aa) |
| | Sros_4018 | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; KEGG: dar:Daro_2822 AMP-dependent synthetase and ligase. (391 aa) |
| | Sros_4169 | Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (619 aa) |
| | glyS | Glycine--tRNA ligase; KEGG: hypothetical protein; K01878 glycyl-tRNA synthetase alpha chain. (1024 aa) |
| | Sros_4302 | Prolyl-tRNA synthetase-like protein; KEGG: Prolyl-tRNA synthetase; K01881 prolyl-tRNA synthetase. (474 aa) |
| | Sros_4529 | CTP synthase; KEGG: ent:Ent638_1664 hypothetical protein. (251 aa) |
| | Sros_4878 | KEGG: acp:A2cp1_3209 AMP-dependent synthetase and ligase. (530 aa) |
| | Sros_5079 | KEGG: spe:Spro_2474 AMP-dependent synthetase and ligase. (511 aa) |
| | Sros_5254 | Asparagine synthase (glutamine-hydrolyzing); KEGG: scl:sce4939 hypothetical protein. (597 aa) |
| | Sros_5591 | Cobaltochelatase; KEGG: pau:PA14_25970 cobaltochelatase. (1207 aa) |
| | rtcB | KEGG: scl:sce1954 hypothetical protein; Belongs to the RtcB family. (511 aa) |
| | pafA | Hypothetical protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. (452 aa) |
| | cobB | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (478 aa) |
| | mshC | Cysteine--tRNA ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (407 aa) |
| | Sros_5953 | KEGG: psa:PST_0623 AMP-dependent synthetase and ligase. (612 aa) |
| | tyrS | Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (422 aa) |
| | argG | KEGG: bha:BH3187 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa) |
| | Sros_6078 | KEGG: pla:Plav_0558 AMP-dependent synthetase and ligase. (553 aa) |
| | pheT | Phenylalanine--tRNA ligase; KEGG: ank:AnaeK_1907 phenylalanyl-tRNA synthetase, beta subunit. (838 aa) |
| | pheS | Phenylalanine--tRNA ligase; KEGG: cja:CJA_2526 phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (365 aa) |
| | alaS | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (890 aa) |
| | aspS-2 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (578 aa) |
| | hisS | Histidine--tRNA ligase; KEGG: noc:Noc_0902 histidyl-tRNA synthetase, class IIA. (421 aa) |
| | thrS | KEGG: mgm:Mmc1_0363 threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (659 aa) |
| | Sros_6279 | KEGG: mxa:MXAN_1276 glutamate-cysteine ligase, family 2. (478 aa) |
| | Sros_6357 | KEGG: ppu:PP_4065 propionyl-CoA carboxylase. (527 aa) |
| | Sros_6413 | KEGG: bph:Bphy_3561 propionyl-CoA carboxylase. (522 aa) |
| | Sros_6618 | KEGG: bch:Bcen2424_0116 AMP-dependent synthetase and ligase. (493 aa) |
| | Sros_6710 | KEGG: afw:Anae109_4038 ATP-dependent DNA ligase. (346 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (845 aa) |
| | Sros_6823 | KEGG: pzu:PHZ_c0733 acyl-CoA synthetase (AMP- forming)/AMP-acid ligase I. (492 aa) |
| | Sros_6948 | KEGG: geo:Geob_0200 benzoate-CoA ligase family. (535 aa) |
| | leuS | KEGG: glo:Glov_2116 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (828 aa) |
| | Sros_7147 | KEGG: spe:Spro_2474 AMP-dependent synthetase and ligase. (511 aa) |
| | lig | ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (508 aa) |
| | Sros_7286 | KEGG: gur:Gura_3277 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (440 aa) |
| | valS-2 | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (861 aa) |
| | Sros_7497 | Glutamate--ammonia ligase; KEGG: rce:RC1_1466 gamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family. (445 aa) |
| | Sros_7941 | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; KEGG: hypothetical protein. (257 aa) |
| | Sros_7973 | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; KEGG: bcm:Bcenmc03_6505 acyl-CoA ligase (AMP- forming), exosortase system type 1 associated. (280 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (369 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (455 aa) |
| | gatB | aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (501 aa) |
| | gatA | Amidase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (496 aa) |
| | gatC | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (99 aa) |
| | ligA-2 | DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (726 aa) |
| | Sros_8199 | KEGG: dol:Dole_2118 AMP-dependent synthetase and ligase. (522 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (240 aa) |
| | cysS-2 | Cysteine--tRNA ligase; KEGG: bur:Bcep18194_B0590 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (459 aa) |
| | metG | tRNA synthetase class I (I, L, M and V); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (593 aa) |
| | Sros_8650 | KEGG: mrd:Mrad2831_5362 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (193 aa) |
| | glyS-2 | Glycine--tRNA ligase; KEGG: hypothetical protein; K01878 glycyl-tRNA synthetase alpha chain. (991 aa) |
| | Sros_8886 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (190 aa) |
| | argS | Arginine--tRNA ligase; KEGG: scl:sce7660 hypothetical protein. (584 aa) |
| | purA-2 | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (406 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (81 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (227 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (765 aa) |
| | purM | KEGG: mgm:Mmc1_2316 phosphoribosylformylglycinamidine cyclo-ligase. (341 aa) |
| | Sros_9080 | Uncharacterized enzyme; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (386 aa) |
| | lysS-2 | KEGG: bsu:BSU00820 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (500 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase-like protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (337 aa) |
| | Sros_9272 | Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; KEGG: dar:Daro_2822 AMP-dependent synthetase and ligase. (647 aa) |
| | argG-2 | KEGG: lch:Lcho_0912 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (482 aa) |
| | ddl-2 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (318 aa) |
