STRINGSTRING
Sros_0004 Sros_0004 Sros_0391 Sros_0391 Sros_0733 Sros_0733 Sros_0777 Sros_0777 Sros_1163 Sros_1163 Sros_1389 Sros_1389 rbsK rbsK Sros_2754 Sros_2754 pfp pfp Sros_2830 Sros_2830 Sros_3371 Sros_3371 edd edd zwf zwf Sros_3959 Sros_3959 Sros_3976 Sros_3976 Sros_5418 Sros_5418 Sros_5639 Sros_5639 Sros_6013 Sros_6013 tal tal Sros_6015 Sros_6015 zwf-2 zwf-2 pgl pgl rbsK-2 rbsK-2 Sros_7320 Sros_7320 Sros_7727 Sros_7727 Sros_8487 Sros_8487 prs prs Sros_9336 Sros_9336
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sros_0004KEGG: dde:Dde_3470 6-phosphogluconate dehydrogenase- like protein. (313 aa)
Sros_0391Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
Sros_0733KEGG: eba:ebA3224 putative ribose-phosphate pyrophosphokinase. (314 aa)
Sros_0777Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (322 aa)
Sros_1163Tagatose-bisphosphate aldolase; KEGG: aha:AHA_0805 tagatose bisphosphate family class II aldolase. (274 aa)
Sros_1389Mannose-6-phosphate isomerase; KEGG: tmz:Tmz1t_0879 KpsF/GutQ family protein. (368 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (318 aa)
Sros_2754KEGG: sus:Acid_6335 hypothetical protein. (314 aa)
pfpDiphosphate--fructose-6-phosphate1-phosphotransf erase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)
Sros_2830Ribulose-phosphate 3-epimerase; KEGG: gme:Gmet_0067 ribulose-5-phosphate 3- epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (218 aa)
Sros_3371KEGG: avi:Avi_3816 keto-hydroxyglutarate- aldolase/keto-deoxy-phosphogluconate aldolase. (203 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (626 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
Sros_39596-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (476 aa)
Sros_3976Gluconokinase; KEGG: afw:Anae109_0595 carbohydrate kinase. (237 aa)
Sros_5418Phosphoketolase; KEGG: neu:NE2135 putative phosphoketolase. (771 aa)
Sros_5639KEGG: ccs:CCNA_00083 phosphoglucomutase/phosphomannomutase. (545 aa)
Sros_6013Tkt1; KEGG: dat:HRM2_48140 Tkt1; Belongs to the transketolase family. (723 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (367 aa)
Sros_6015KEGG: sfu:Sfum_1952 phosphoglucose isomerase (PGI); Belongs to the GPI family. (542 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (545 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (257 aa)
rbsK-2Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (299 aa)
Sros_7320KEGG: gme:Gmet_2621 ribose/galactose isomerase. (169 aa)
Sros_7727KEGG: bvi:Bcep1808_1677 ribokinase-like domain- containing protein. (314 aa)
Sros_8487Fructose-bisphosphatase; KEGG: dat:HRM2_21890 GlpX. (344 aa)
prsRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
Sros_9336Gluconolactonase; KEGG: mlo:mll4328 gluconolactonase. (299 aa)
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.